Polymers,
Journal Year:
2024,
Volume and Issue:
16(23), P. 3353 - 3353
Published: Nov. 29, 2024
In
this
work,
new
materials
based
on
the
blends
of
polyvinyl
alcohol
(PVA),
pyrrolidone
(PVP),
chitosan
(CS),
and
polydopamine
(PDA)
have
been
prepared.
Fourier
Transform
Infrared
Spectra
conducted
to
verify
presence
individual
components
in
composite
materials.
EDX
elemental
analysis
showed
a
clear
view
element’s
materials,
with
maximum
values
for
carbon
oxygen.
Atomic
force
microscopy
(AFM)
was
used
observe
surface
topography
measure
roughness.
case
polymers,
CS
presented
higher
value
roughness
(Rq
=
3.92
nm
Ra
3.02
nm),
found
be
lowest
it
2.34
0.95
nm).
PVA
films
roughness,
which
3.38
2.11
composites,
highest
PVA,
PVP,
CS,
11.91
8.71
After
addition
polymeric
reduction
observed
7.49
5.15
The
than
that
polymers.
PDA
(PVA/PVP/CS)
led
decrease
Young’s
modulus.
elongation
percentage
PVA/PVP/CS/PDA
blend
without
(9.80%
vs.
5.68%
PVA/PVP/CS).
hydrophilic.
results
from
MTT
assay
all
tested
specimens
are
non-toxic,
manifested
by
significant
increase
viability
L929
cells
compared
control
cells.
However,
additional
studies
required
check
biocompatibility
samples.
This
study
explores
the
synergistic
effects
of
combining
titania
nanotubes
(TiNTs)
with
biopolymer
Tanfloc
(TAN)
to
enhance
surface
properties
TiNTs
for
biomedical
applications.
We
investigated
interactions
blood
components
and
human
adipose-derived
stem
cells
(ADSCs)
TiNT
surfaces
covalently
functionalized
(TAN),
an
aminolyzed
polyphenolic
tannin
derivative.
The
(TiNT-TAN)
have
great
potential
control
protein
adsorption
platelet
adhesion
activation.
Fluorescence
scanning
electron
microscopy
(SEM)
were
used
analyze
adherence
amphoteric
nature
multiple
functional
groups
on
TAN
can
adsorption,
adhesion,
Further,
modified
supports
cell
(ADSC)
viability,
attachment,
growth
without
any
cytotoxic
effect.
conjugation
significantly
(****p
<
0.0001)
increased
proliferation
rate
ADSCs
compared
surfaces.
Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(25), P. 10434 - 10442
Published: June 12, 2024
Plasma
protein
adsorption
on
blood-contacting
surfaces
is
the
initiating
significant
event
and
modulates
subsequent
coagulation
response.
Despite
decades
of
research
in
this
area,
Vroman's
questions
1986
"Who
gets
there
first?"
"When
does
next
arrive?"
remain
unanswered
due
to
lack
detection
techniques
with
sufficient
temporal
resolution.
In
work,
we
develop
a
droplet
microfluidic
technology
detect
sequences
six
typical
milliseconds.
Apolipoproteins
(Apo)
are
found
be
first
proteins
adsorb
onto
plasma
droplet,
specific
type
apolipoprotein
depends
surface.
Apo
CI
adsorbed
gold,
platinum,
graphene,
stainless
steel,
polyvinyl
chloride
time
varying
from
0.01
1
s,
while
CIII
preferentially
reaches
titanium
alloy
surface
within
s.
Subsequent
initial
adsorption,
AI,
AII,
other
continue
until
albumin
arrives.
Thus,
sequence
revealed,
answered.
Moreover,
finding
demonstrates
influence
at
surface,
it
offers
new
insights
into
development
anticoagulant
surfaces.
Biomedical Materials,
Journal Year:
2024,
Volume and Issue:
19(5), P. 055040 - 055040
Published: Aug. 2, 2024
The
role
of
blood
clots
in
tissue
repair
has
been
identified
for
a
long
time;
however,
its
participation
the
integration
between
implants
and
host
tissues
attracted
attention
only
recent
years.
In
this
work,
mesoporous
silica
thin
film
(MSTF)
with
either
vertical
or
parallel
orientation
was
deposited
on
titania
nanotubes
surface,
resulting
superhydrophilic
nanoporous
surfaces.
A
proteomic
analysis
plasma
adsorption
revealed
that
MSTF
coating
could
significantly
increase
abundance
acidic
proteins
coagulation
factors
(XII
XI),
help
cations
(Na
