Asymmetric Three-Component Radical Alkene Carboazidation by Direct Activation of Aliphatic C–H Bonds

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: 146(19), P. 13347 - 13355

Published: May 6, 2024

Azide compounds are widely present in natural products and drug molecules, their easy-to-transform characteristics make them used the field of organic synthesis. The merging transition-metal catalysis with radical chemistry offers a versatile platform for carboazidation alkenes, allowing rapid assembly highly functionalized azides. However, direct use readily available hydrocarbon feedstocks as sp

Language: Английский

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Anti-Markovnikov hydro- and deuterochlorination of unsaturated hydrocarbons using iron photocatalysis

Nature Synthesis, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Language: Английский

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Unleashing the potentiality of metals: synergistic catalysis with light and electricity

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(14), P. 4024 - 4040

Published: Jan. 1, 2024

This review provides a comprehensive overview of metal catalysis in photo-electrochemical systems, discussing reaction mechanisms and offering prospects for this triadic catalytic mode.

Language: Английский

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Unraveling the Prominent Existence of Trace Metals in Photocatalysis: Exploring Iron Impurity Effects

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(6), P. 4156 - 4164

Published: March 7, 2024

Metal impurities can complicate the identification of active catalyst species in transition metal catalysis and electrocatalysis, potentially leading to misleading findings. This study investigates influence on photocatalysis. Specifically, photocatalytic reaction inert alkanes using chlorides without use an external photocatalyst was studied, achieving successful C(sp

Language: Английский

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Towards a more Sustainable Photocatalysis using Copper and Iron

Current Opinion in Green and Sustainable Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 100998 - 100998

Published: Jan. 1, 2025

Language: Английский

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Simple, catalytic C(sp³)–H azidation using the C–H donor as the limiting reagent

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(27), P. 3705 - 3708

Published: Jan. 1, 2024

C(sp 3 )–H bonds can be directly azidated using simple iron and manganese catalysts commercial Selectfluor TMSN as reagents.

Language: Английский

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Mechanochemistry Drives Alkene Difunctionalization via Radical Ligand Transfer and Electron Catalysis

Advanced Science, Journal Year: 2024, Volume and Issue: 11(29)

Published: June 3, 2024

Abstract A general and modular protocol is reported for olefin difunctionalization through mechanochemistry, facilitated by cooperative radical ligand transfer (RLT) electron catalysis. Utilizing mechanochemical force catalytic amounts of 2,2,6,6‐tetramethylpiperidinyloxyl (TEMPO), ferric nitrate can leverage nitryl radicals, nitrooxy‐functional group via RLT, mediate an catalysis cycle under room temperature. diverse range activated unactivated alkenes exhibited chemo‐ regioselective 1,2‐nitronitrooxylation solvent‐free or solvent‐less conditions, showcasing excellent functional tolerance. Mechanistic studies indicated a significant impact mechanochemistry highlighted the nature this nitrative process.

Language: Английский

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Photocatalytic C–P bond formation based on the reaction of carbon-centered radicals with phosphides

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(17), P. 4882 - 4894

Published: Jan. 1, 2024

This review focuses on the synthesis of C–P bonds using carbon-centered radicals with phosphorous compounds different valence states (P III , P V 4 ) under photocatalysis.

Language: Английский

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Photoinduced difunctionalizations of unactivated olefins enabled by ligand-to-iron charge transfer and functional group migration strategies

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(17), P. 4748 - 4756

Published: Jan. 1, 2024

Difunctionalizations of unactivated olefins with fluoroalkyl carboxylic acids or aldehydes via a radical-mediated functional group migration strategy are herein reported.

Language: Английский

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Iron Photoredox Catalysis as an Effective Tool for Organic Synthesis via Visible‐Light‐Induced Homolysis (VLIH)

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(4)

Published: Jan. 1, 2025

Abstract Owing to its possible advantages for the environment and economy, photoredox catalysis of organic processes fueled by iron has garnered a lot interest recently. The potential photo‐induced single‐electron transfer (SET) events occurring outside sphere is now well acknowledged. Currently, focus shifted newly discovered photoactivation method that based on an inner‐sphere mode reactivity caused population visible‐light‐induced homolysis (VLIH) states. VLIH activation, in contrast photoredox, specific complexes, offers distinct profiles, does not require redox potentials coincide. These attractive properties have prompted development strategies use this blueprint manufacture highly reactive open‐shell species mild environments. purpose contribution promote novel synthetic techniques sustainable chemical transformations offer educational instrument understanding evolving idea.

Language: Английский

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