Reviewing
photocatalytic
and
metal-catalyzed
disulfide
synthesis,
2021–2024,
emphasizes
efficiency,
selectivity,
sustainability
for
drug
material
science.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(18), P. 5278 - 5305
Published: Jan. 1, 2024
This
review
summarizes
the
latest
methodological
advances
in
photocatalytic
C(sp
3
)–H
functionalization,
with
a
particular
emphasis
on
formation
of
C–P,
C–B,
C–S
bonds,
etc
.,
and
some
prominent
efforts
asymmetric
C–H
functionalization.
Organic & Biomolecular Chemistry,
Journal Year:
2024,
Volume and Issue:
22(30), P. 6198 - 6204
Published: Jan. 1, 2024
Reported
herein
is
a
visible-light
induced
selenocyclization
of
2-ethynylanilines
under
ambient
conditions,
with
simple
FeBr
3
as
dual-functional
catalyst.
Organic & Biomolecular Chemistry,
Journal Year:
2024,
Volume and Issue:
22(33), P. 6650 - 6664
Published: Jan. 1, 2024
Titanium,
as
an
important
transition
metal,
has
garnered
extensive
attention
in
both
industry
and
academia
due
to
its
excellent
mechanical
properties,
corrosion
resistance,
unique
reactivity
organic
synthesis.
In
the
field
of
photocatalysis,
titanium-based
compounds
such
titanium
dioxide
(TiO
A
novel
ligand-to-metal
charge
transfer
(LMCT)-based
synthetic
methodology
is
presented
for
the
decarboxylative
hydrogenation
of
aromatic
carboxylic
acids.
This
approach
features
mild
reaction
conditions,
economical
copper-mediated
catalysis,
and
exceptional
functional
group
tolerance.
The
study
addresses
significant
challenges
in
acid
transformations
underscores
potential
photochemical
copper
catalysis
contemporary
organic
synthesis..
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
366(21), P. 4263 - 4273
Published: Aug. 28, 2024
Abstract
Aryl
radicals
are
important
intermediates
in
organic
synthesis.
The
generation
of
these
reactive
species
via
direct
decarboxylation
inexpensive
and
readily
available
aromatic
carboxylic
acids
is
an
attractive
goal.
However,
such
a
process
intrinsically
exhibits
high
energy
barriers
to
overcome,
which
consequence
usually
require
precious
metal
catalysis,
stoichiometric
oxidants
harsh
conditions,
suffering
from
limitations
as
poor
functional
group
tolerance
low
atom
economy.
In
recent
years,
photochemical
reactions
have
provided
new
approaches
address
this
challenge.
Three
major
strategies
been
introduced
emerging
field:
1)
one‐pot
in‐situ
activation
benzoic
generate
benzoyl
hypobromites
or
hypoiodites;
2)
the
use
specialized
photocatalysts
like
biphenyl/1,4‐dicyanobenzene
promote
through
photo‐induced
electron
transfer
charge
processes;
3)
LMCT
(Ligand‐to‐Metal
Charge
Transfer)
strategy
where
copper
iron
salts
coordinate
carboxylate
anion
upon
visible
light
excitation.
On
basis
three
strategies,
review
will
systematically
summarize
development
visible‐light‐induced
decarboxylative
functionalization
acids,
focusing
on
reaction
mechanism
substrate
scope,
discuss
their
prospects
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
366(22), P. 4618 - 4633
Published: Oct. 16, 2024
Abstract
Germanium
(Ge),
a
congener
of
carbon,
possesses
unique
properties
that
hold
extensive
potential
for
applications
across
multiple
domains.
Recent
years
have
seen
significant
progress
in
the
development
carbon‐germanium
bond
formation
strategies,
particularly
those
more
challenging
C(
sp
3
)−Ge
bonds.
This
review
systematically
summarizes
recent
advances
forming
methodologies,
with
particular
emphasis
on
(1)
versatility
transition‐metals,
including
iron,
nickel,
copper,
rhodium
and
palladium,
as
catalysts
broadening
reaction
scope
controlling
selectivity;
(2)
powerfulness
organic
photocatalysis
achieving
mild
selective
formation,
(3)
sustainability
catalytic
electrosynthesis
facilitating
chemical
oxidant‐/reductant‐
free
conversions.
Additionally,
examples
(4)
non‐catalytic
strategies
are
also
discussed.
The
representative
scopes,
well
mechanistic
proposals,
these
protocols
highlighted.
Through
an
overview
current
state
research,
this
aims
to
offer
insights
into
construction
bonds,
provide
perspectives
future
research
directions
address
challenges.
