Exploring HSA binding of Irinotecan-Functionalised silver Nanoparticles: Insights from spectroscopic and calorimetric approaches DOI
Aparna Raj,

L. Vidya,

V M Aparna

et al.

Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: unknown, P. 126796 - 126796

Published: Dec. 1, 2024

Language: Английский

Bioremediation strategies and mechanisms of bacteria for resistance against heavy metals: a review DOI
Anjali Patil, Sudip Chakraborty,

Yuvraj Yadav

et al.

Bioremediation Journal, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 33

Published: July 12, 2024

Language: Английский

Citations

7
The endothelial surface layer-glycocalyx - Universal nano-infrastructure is fundamental to physiology, cell traffic and a complementary neural network DOI Creative Commons
Barry W. Ninham, N. F. Bunkin, Matthew Battye

et al.

Advances in Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 338, P. 103401 - 103401

Published: Jan. 18, 2025

Language: Английский

Citations

0
An NMR Toolkit to Probe Amyloid Oligomer Inhibition in Neurodegenerative Diseases: From Ligand Screening to Dissecting Binding Topology and Mechanisms of Action DOI
Alessandro Palmioli, Cristina Airoldi

ChemPlusChem, Journal Year: 2024, Volume and Issue: unknown

Published: May 7, 2024

The aggregation of amyloid peptides and proteins into toxic oligomers is a hallmark neurodegenerative diseases, such as Alzheimer's disease, Parkinson's Machado-Joseph's transmissible spongiform encephalopathies. Inhibition formation interactions with biological counterparts, well the triggering non-toxic amorphous aggregates, are strategies towards preventive interventions against these pathologies. NMR spectroscopy addresses need for structural characterization their binding to inhibitors, rapid screening compound libraries ligand identification. Here we briefly discuss solution experiments constituting spectroscopist's toolkit provide examples application.

Language: Английский

Citations

1
Interplay of Metal Ions and Posttranslational Modifications in Proteins DOI
Massimiliano Peana, Tomasz Frączyk, Maria Antonietta Zoroddu

et al.

European Journal of Inorganic Chemistry, Journal Year: 2024, Volume and Issue: 27(31)

Published: Aug. 19, 2024

Abstract Posttranslational modifications (PTMs) and metal ions are integral players in the complex regulatory orchestra governing protein function. Several ions, including zinc, iron, copper, others, intricately influence structure activity as cofactors. Concurrently, PTMs, such phosphorylation, acetylation, ubiquitination, add an additional layer of complexity to proteome, dynamically shaping cellular responses. Understanding this bidirectional relationship is crucial for unraveling web regulation. This review explores reciprocal impact on PTMs vice versa provides examples insights into how modulate and, conversely, metal‐binding proteins, shedding light crosstalk between these two facets biology. interplay not only central homeostasis but also holds implications diseases associated with dysregulated metal‐ion PTM processes.

Language: Английский

Citations

1
Review of Cobalt-Based Nanomaterials as Sensors for Water Contaminants DOI
Jun Luo, Yonghai Gan, Bin Xu

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(17), P. 19784 - 19802

Published: Sept. 4, 2024

Language: Английский

Citations

1
Investigating the Genetic Association of 40 Biochemical Indicators with Parkinson’s Disease DOI
Zihao Wang, Huan Xia,

Jianqiao Shi

et al.

Journal of Molecular Neuroscience, Journal Year: 2024, Volume and Issue: 74(4)

Published: Oct. 4, 2024

Language: Английский

Citations

1
Exploring HSA binding of Irinotecan-Functionalised silver Nanoparticles: Insights from spectroscopic and calorimetric approaches DOI
Aparna Raj,

L. Vidya,

V M Aparna

et al.

Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: unknown, P. 126796 - 126796

Published: Dec. 1, 2024

Language: Английский

Citations

0