Nanotechnology in healthcare, and its safety and environmental risks

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: Nov. 15, 2024

Abstract Nanotechnology holds immense promise in revolutionising healthcare, offering unprecedented opportunities diagnostics, drug delivery, cancer therapy, and combating infectious diseases. This review explores the multifaceted landscape of nanotechnology healthcare while addressing critical aspects safety environmental risks associated with its widespread application. Beginning an introduction to integration we first delved into categorisation various materials employed, setting stage for a comprehensive understanding potential. We then proceeded elucidate diverse applications nanotechnology, spanning medical tissue engineering, targeted gene development antimicrobial agents. The discussion extended current situation surrounding clinical translation commercialisation these cutting-edge technologies, focusing on nanotechnology-based products that have been approved globally date. also discussed considerations nanomaterials, both terms human health impact. presented vivo nanomaterial exposure, relation transport mechanisms, oxidative stress, physical interactions. Moreover, highlighted risks, acknowledging potential implications ecosystems biodiversity. Lastly, strived offer insights regulatory governing across different regions globally. By synthesising perspectives, underscore imperative balancing innovation stewardship, charting path forward responsible healthcare. Graphical abstract

Language: Английский

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Machine learning applications in nanomaterials: Recent advances and future perspectives

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 156687 - 156687

Published: Oct. 1, 2024

Language: Английский

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Graphene metasurface biosensor design for label-free peptide detection with machine learning optimization based on support vector regression with polynomial kernel

Diamond and Related Materials, Journal Year: 2025, Volume and Issue: unknown, P. 112053 - 112053

Published: Jan. 1, 2025

Language: Английский

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Optical Bionanosensors for Sepsis Diagnostics

Small, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Sepsis is a global health challenge, characterized by dysregulated immune response, leading to organ dysfunction and death. Despite advances in medical care, sepsis continues claim significant toll on human lives, with mortality rates from 10-25% for 30-50% septic shock, making it cause of death worldwide. Current diagnostic methods rely clinical signs, laboratory parameters, or microbial cultures suffer delays inaccuracies. Therefore, there pressing need novel tools that can rapidly accurately identify sepsis. This review highlights biosensor development could ultimately lead faster more accurate diagnostics. The focus nanomaterial-based optical approaches promise rapid diagnostics without the large equipment trained personnel. An overview provided, highlighting potential molecular targets challenges they present assay development. requirements an ideal point-of-care test (POC) are discussed, including speed, simplicity, cost-effectiveness. Different nanomaterials suitable various detection reviewed innovative nanosensors discussed diagnostics, focusing chemical design increase selectivity multiplexing.

Language: Английский

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Wearable Textile Sensors for Continuous Glucose Monitoring

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: 273, P. 117133 - 117133

Published: Jan. 5, 2025

Language: Английский

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Biomedical Applications of Metal–Organic Frameworks Revisited

Industrial & Engineering Chemistry Research, Journal Year: 2025, Volume and Issue: 64(4), P. 1907 - 1932

Published: Jan. 14, 2025

Metal–organic frameworks (MOFs) have been shown to be great alternatives traditional porous materials in various chemical applications, and they very widely studied for biomedical applications the past decade specifically drug storage. After our review published 2011 [Keskin Kızılel, Ind. Eng. Chem. Res. 2011, 50 (4), 1799–1812, 10.1021/ie101312k], we witnessed a fast growth not only number variety of MOFs but also their usage across broad spectrum fields. With recent integration molecular modeling data science approaches experimental studies, significantly accelerated positioning them as pivotal components regenerative medicine, medical imaging, diagnostics. In this review, visited diverse considering computational efforts on storage delivery, bioimaging, biosensing. We focused underlying mechanisms governing interactions between biological systems discussed both opportunities challenges field highlight potential advanced therapeutics cancer neurological diseases.

Language: Английский

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Rational Design of Bio‐Inspired Peptide Electronic Materials toward Bionanotechnology: Strategies and Applications

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(29)

Published: March 18, 2024

Abstract Biologically inspired peptide‐based materials, as novel charge transport have gained increasing interest in bioelectronics due to their remarkable electrical properties and inherent biocompatibility. Extensive studies shown that peptides can self‐assemble into a variety of hierarchical nanostructures with unique physical through supramolecular interactions. Therefore, materials hold great promise for applications emerging electronic fields such sensing, energy harvesting, storage, transmission. Herein, this work proposes review article summarize the rational design research progress devices bioelectronics. This first introduces strategies assembly mechanism constructing high‐performance devices. In following part, are systematically classified discussed, including sensors, piezoelectric nanogenerators, electrodes, semiconductors. Finally, remaining challenges future perspectives bioelectronic presented. believes will provide inspiration guidance development innovative smart field

Language: Английский

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What is the role of microbial biotechnology and genetic engineering in medicine?

MicrobiologyOpen, Journal Year: 2024, Volume and Issue: 13(2)

Published: March 31, 2024

Abstract Microbial products are essential for developing various therapeutic agents, including antibiotics, anticancer drugs, vaccines, and enzymes. Genetic engineering techniques, functional genomics, synthetic biology unlock previously uncharacterized natural products. This review highlights major advances in microbial biotechnology, focusing on gene‐based technologies medical applications.

Language: Английский

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Near-Infrared-Responsive Photoelectrochemical Biosensors

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 179, P. 117890 - 117890

Published: July 30, 2024

Language: Английский

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Next-Generation Nanomaterials-based Biosensors: Real-Time Biosensing Devices for Detecting Emerging Environmental Pollutants

Materials Today Sustainability, Journal Year: 2024, Volume and Issue: unknown, P. 101068 - 101068

Published: Dec. 1, 2024

Language: Английский

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