Engineering Fracture Mechanics, Journal Year: 2024, Volume and Issue: unknown, P. 110747 - 110747
Published: Dec. 1, 2024
Language: Английский
Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 123 - 123
Published: Feb. 7, 2025
Recent advancements in wound dressing materials have significantly improved acute and chronic management by addressing challenges such as infection control, moisture balance, enhanced healing. Important progress has been made, especially with hydrogels, foams, antimicrobial for creating optimized dressings. Hydrogels are known maintaining optimal levels, while foam dressings excellent exudate absorbents. Meanwhile, incorporates various agents to reduce risks. These options healing time focusing on customized patient needs. Therefore, this review highlights the newest research prototypes applications, emphasizing their particular benefits clinical importance. Innovations stimuli-responsive hydrogels hybrid bioengineered composites discussed relation properties, including responsiveness pH, temperature, glucose, or enzymes drug delivery precision. Moreover, ongoing trials included, demonstrating potential of emerging solutions be soon translated from laboratory settings. By discussing interdisciplinary approaches that integrate advanced materials, nanotechnology, biological insights, work provides a contemporary framework patient-centric, efficient care strategies.
Language: Английский
Citations
8
Gels, Journal Year: 2024, Volume and Issue: 10(11), P. 693 - 693
Published: Oct. 25, 2024
Hydrogels are known for their high water retention capacity and biocompatibility have become essential materials in tissue engineering drug delivery systems. This review explores recent advancements hydrogel technology, focusing on innovative types such as self-healing, tough, smart, hybrid hydrogels, each engineered to overcome the limitations of conventional hydrogels. Self-healing hydrogels can autonomously repair structural damage, making them well-suited applications dynamic biomedical environments. Tough designed with enhanced mechanical properties, enabling use load-bearing cartilage regeneration. Smart respond external stimuli, including changes pH, temperature, electromagnetic fields, ideal controlled release tailored specific medical needs. Hybrid made from both natural synthetic polymers, combine bioactivity resilience, which is particularly valuable complex tissues. Despite these innovations, challenges optimizing biocompatibility, adjusting degradation rates, scaling up production remain. provides an in-depth analysis emerging technologies, highlighting transformative potential while outlining future directions development applications.
Language: Английский
Citations
13
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 500, P. 157299 - 157299
Published: Nov. 1, 2024
Language: Английский
Citations
10
The International Journal of Lower Extremity Wounds, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 8, 2025
Diabetic foot ulcer (DFU) is a common complication of diabetes, associated with increased rates amputation and mortality. In recent years, great progress has been made in the treatment DFU, but there still lack bibliometric research on DFU.DFU therapy publications published between 1 January 2004 31 December 2023 were retrieved from Web Science Core Collection (WoSCC) database for analysis using VOSviewer CiteSpace analytics. A total 4833 DFU to included WoSCC database. The United States had highest productivity 1463 papers, accounting 30.27% production, followed by China 907 papers (18.77%) England 438 (9.06%). terms institutions journals, University Texas System Journal Wound Care number papers. High-frequency keywords field mainly concentrated management, wound healing, amputation. This study conducted systematic 2025. Improving promoting reducing are hotspots future trends this field. Our work provides valuable insights into trajectory avenues exploration therapy. These findings provide strong support academic clinical practice.
Language: Английский
Citations
1
Acta Biomaterialia, Journal Year: 2024, Volume and Issue: 192, P. 431 - 445
Published: Dec. 9, 2024
Language: Английский
Citations
4
Macromolecular Bioscience, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 7, 2025
Annually, thousands of individuals suffer from skin injuries resulting trauma, surgeries, or diabetes. Inadequate wound treatment can delay healing and increase the risk severe infections. In this context, a promising synthetic polymer with potent antimicrobial properties, Poly{2-[(methacryloyloxy)ethyl]trimethylammonium chloride} (PMETAC), is synthesized crosslinked N,N'-Methylenebis(acrylamide) (BIS) in presence Chitosan (CH), natural, biocompatible polysaccharide that promotes cell regeneration provides additional beneficial properties. These semi-interpenetrating (semi-IPN) networks are chosen as matrix for releasing papain, proteolytic enzyme debridement By integrating properties materials, study evaluates PMETAC-based hydrogels different CH concentrations (5%, 10%, 25%) to understand their physicochemical biological performance, including antibacterial activity cytocompatibility. incorporating 25% led 19% pore size 48% maximum volume compared control PMETAC hydrogel. Additionally, all formulations demonstrate ≈100% reduction E. coli S. aureus, showcasing remarkable efficacy. The inclusion also significantly improves fibroblast viability, formulation standing out most candidate multifunctional dressings, highlighting potential hard-to-heal wounds regenerative medicine.
Language: Английский
Citations
0
The International Journal of Lower Extremity Wounds, Journal Year: 2025, Volume and Issue: unknown
Published: March 13, 2025
Diabetic foot ulcer (DFU) is a common complication of diabetes. It often accompanied by infection and, in severe cases, necessitates amputation. Early diagnosis and monitoring are crucial for improving prognosis. Novel inflammatory biomarkers, such as the systemic response index (SIRI), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR) useful predicting prognosis some diseases. This study aimed to clarify association between SIRI, NLR, PLR DFU assess their utility early DFU. Cross-sectional data were extracted on individuals with diabetes who participated National Health Nutrition Examination Survey (NHANES) 1999 2004. was diagnosed based presence ulcers that had not healed within 4 weeks. Weighted multivariable regression, subgroup analysis, smooth curve fitting used evaluate relationships DFU.A total 1204 participants included whom 112 DFUs. Participants DFUs higher PLR, SIRI values than those without For each unit increase prevalence increased 27% . Subgroup analyses showed consistent an elevated DFUs.SIRI low-cost, readily accessible biomarker can be conjunction NLR severity predict Continuous these indicators could assist management
Language: Английский
Citations
0
Advances in Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 341, P. 103481 - 103481
Published: March 19, 2025
Language: Английский
Citations
0
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 143471 - 143471
Published: April 1, 2025
Language: Английский
Citations
0
Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112903 - 112903
Published: May 1, 2025
Language: Английский
Citations
0