Functional covalent organic framework H₂S sensors for periodontitis monitoring and antibacterial treatment

New Journal of Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Incorporating the indicator (PB) and COF (EB-TFP), IDA-based fluorescence-enhanced gas sensor (EB-TFP@PB) exhibited selective binding with H 2 S. EB-TFP@PB showed antibacterial activity against aureus under non-illuminated conditions.

Language: Английский

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Albumin host for supramolecular fluorescence recognition

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Synthetic molecular sensors are crucial for real-time monitoring in biological systems and biotechnological applications, where detecting targets amidst potential interferents is essential.

Language: Английский

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Review of the Hazards and Contraindications of Etomidate

International Journal of Toxicology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 6, 2024

Etomidate, an ultrashort-acting non-barbiturate sedative derived from imidazole, exerts potent inhibitory effects on the central nervous system. It is commonly employed for induction of intravenous general anaesthesia or assisted anaesthesia. Recently, etomidate has emerged as alternative to narcotics and novel psychoactive substances, leading increasing trend abuse. Chronic overdose can result in irreversible brain damage various mental disorders. Severe cases may manifest disturbances, behavioural disorders, self-mutilation even death. The toxicological mechanisms remain poorly understood. Additionally, there limited information clinical symptoms histopathological changes associated with poisoning standardized detection methods blood, urine hair are lacking. Consequently, further research pathology development reliable testing crucial. This study reviews metabolism, distribution, adverse reactions, manifestations, toxicology etomidate.

Language: Английский

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Au Ordered Array Substrate for Rapid Detection and Precise Identification of Etomidate in E-Liquid Through Surface-Enhanced Raman Spectroscopy

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(23), P. 1958 - 1958

Published: Dec. 6, 2024

Etomidate (ET), a medical anesthetic, is increasingly being incorporated into e-liquids for consumption and abuse as new psychoactive substance (NPS), leading to significant social issues. In this work, large-area Au micro- nano-structured ordered arrays were engineered surface-enhanced Raman spectroscopy (SERS) substrates fast detection precise identification of ET its metabolites. This array, characterized by abundant electromagnetic enhancement hotspots structural uniformity, imparts unique properties the SERS substrate, including ultra-sensitivity, spectral signal reproducibility, quantitative capabilities. Furthermore, it effectively mitigates interference from complex matrix e-liquids, facilitating rapid trace amounts molecules. technology can act preliminary screening method gold-standard spectroscopic analysis, on-site suspicious samples thereby enabling efficient verification.

Language: Английский

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Boosting the smartphone-assisted on-site monitoring capacity for nitroxynil by using synergistic fluorescent sensing system

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(69), P. 9226 - 9229

Published: Jan. 1, 2024

A novel ratiometric analytical method based on a quantum dot (QD)-integrated supramolecular sensing system successfully achieves the portable on-site detection of nitroxynil.

Language: Английский

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Rational design of a ratiometric indicator-displacement assay for the monitoring of chlortetracycline and intracellular imaging

Talanta, Journal Year: 2024, Volume and Issue: 284, P. 127251 - 127251

Published: Nov. 19, 2024

Language: Английский

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