Palladium-catalysed alleneamination of γ,δ-unsaturated hydrazones with propargylic acetates: access to tetrahydropyridazines bearing allenes

Chemical Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Herein, we reported a palladium-catalysed alleneamination of γ,δ-unsaturated hydrazones with propargylic acetates, which provides an efficient approach for the synthesis tetrahydropyridazine bearing allenes in moderate to good yields.

Language: Английский

Access to C5-Sulfonylated Tetrahydropyridazines via Photoinduced Cascade Sulfonylation-Cyclization of N-Cinnamyl Aldehyde Hydrazones

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Direct installation of a sulfonyl functional group into the C5-position tetrahydropyridazine was achieved using N'-benzylidene-N-cinnamylacetohydrazide as new building skeleton via photocatalytic carbosulfonylation/annulation procedure. Various substituted C5-sulfonylated tetrahydropyridazines were obtained in good to excellent yields employing aryl- or alkylsulfonyl chlorides radical sources. This reaction realized through selective addition C2 position cinnamyl followed by 6-endo-trig annulation hydrazone CH═N bond.

Language: Английский

Assembling Molecular Semiconductor Composite for Enhanced Photocatalytic Cyclohexene Oxidation

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

A molecular semiconductor composite was assembled by integrating atomically precise Ti 12 -oxo clusters and phosphotungstic acid into a cocrystal system.

Language: Английский