Unveiling the Role of JAK2/STAT3 Signaling in Chemoresistance of Gynecological Cancers: From Mechanisms to Therapeutic Implications DOI
Tianxiao Zhang,

Chang Xiaohan

Critical Reviews in Oncology/Hematology, Journal Year: 2025, Volume and Issue: unknown, P. 104712 - 104712

Published: April 1, 2025

Language: Английский

Chitosan-Functionalization Graphene Oxide for Immobilizing Gold Nanoparticles: Application of Its Catalytic Performance in the Reduction of Methylene Blue and Methyl Orange and Investigation of Its Anti-lung Cancer Effects DOI
F. M. Aldosari, Attalla F. El‐kott, Ali Alshehri

et al.

Journal of Inorganic and Organometallic Polymers and Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

Language: Английский

Citations

0
Prunin: An Emerging Anticancer Flavonoid DOI Open Access
Juie Nahushkumar Rana, Sohail Mumtaz

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(6), P. 2678 - 2678

Published: March 16, 2025

Despite the substantial advances in cancer therapies, developing safe and effective treatment methodologies is critical. Natural (plant-derived compounds), such as flavonoids, might be crucial a methodology without toxicity toward healthy tissues. Prunin flavonoid with potential to used biomedical applications. has yet undergo thorough scientific research, its precise molecular mechanisms of action remain largely unexplored. This review summarizes therapeutic prunin for first time, focusing on underlying an anticancer compound. gained significant attention due antioxidant, anti-inflammatory, effects. aims unlock how functions at level exert effects, primarily modulating key cellular pathways. Furthermore, we have discussed prunin’s adjunctive therapy conventional treatments, highlighting ability strengthen responses while decreasing drug resistance. Moreover, discussion probes into innovative delivery methods, particularly nanoformulations, that address bioavailability, solubility, stability limitations optimize application. By providing comprehensive analysis properties, this stimulate further exploration using agent, thereby progressing development targeted, selective, safe, methods.

Language: Английский

Citations

0
Exosomes derived from natural killer cells: transforming immunotherapy for aggressive breast cancer DOI
Abdulmalik Saleh Alfawaz Altamimi, M. Arockia Babu, Muhammad Afzal

et al.

Medical Oncology, Journal Year: 2025, Volume and Issue: 42(4)

Published: March 18, 2025

Language: Английский

Citations

0
Synthesis and DNA binding studies of novel triazine-isatin hybrids: experimental and computational insights DOI Creative Commons
Alia Mushtaq, Muhammad Moazzam Naseer

RSC Advances, Journal Year: 2025, Volume and Issue: 15(11), P. 8443 - 8455

Published: Jan. 1, 2025

A series of novel s -triazine-isatin hybrids 7a–f were synthesized and characterized both experimentally computationally for their DNA binding interactions.

Language: Английский

Citations

0
Tumor microenvironment: recent advances in understanding and its role in modulating cancer therapies DOI
Disha D. Shah, Mehul R. Chorawala, Neha R. Raghani

et al.

Medical Oncology, Journal Year: 2025, Volume and Issue: 42(4)

Published: March 18, 2025

Language: Английский

Citations

0
Innovative colorimetric sensor for detection of nandrolone as a doping agent in sports using MOF nanostructures DOI
Shuai Wang

Alexandria Engineering Journal, Journal Year: 2025, Volume and Issue: 122, P. 605 - 614

Published: March 21, 2025

Language: Английский

Citations

0
Mapping molecular landscapes in triple-negative breast cancer: insights from spatial transcriptomics DOI
Fares Saeed H. Al-Mansour, Hassan H. Almasoudi, Ali Albarrati

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: March 22, 2025

Language: Английский

Citations

0
Liposomes as Immunotherapeutic Carriers: A Game-Changer in Cancer Therapy DOI

Sepehr Hoseinzadeh Moghaddam,

Abulfazl Vatankhah,

Fatemeh Oroojalian

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106847 - 106847

Published: March 1, 2025

Language: Английский

Citations

0
Current Research in Drug-Free Cancer Therapies DOI Creative Commons

Akshaya Andavar,

Varsha Rajesh Bhagavathi,

J Cousin

et al.

Bioengineering, Journal Year: 2025, Volume and Issue: 12(4), P. 341 - 341

Published: March 26, 2025

Cancer treatment has historically depended on conventional methods like chemotherapy, radiation, and surgery; however, these strategies frequently present considerable limitations, including toxicity, resistance, negative impacts healthy tissues. In addressing challenges, drug-free cancer therapies have developed as viable alternatives, utilizing advanced physical biological to specifically target tumor cells while reducing damage normal This review examines several strategies, such high-intensity focused energy beams, nanosecond pulsed electric fields, photothermal therapy well the use of inorganic nanoparticles promote selective apoptosis. We also investigate significance targeting microenvironment, precision medicine, immunotherapy in progression personalized therapies. Although approaches demonstrate significant promise, challenges scalability, safety, regulatory obstacles must be resolved for clinical application. paper presents an overview current research therapies, emphasizing recent advancements, underlying scientific principles, steps required implementation.

Language: Английский

Citations

0
A vascular heterogeneity-orienting TACE strategy addresses peripheral tumor and avascular deep tumor for complete hepatocellular carcinoma clearance DOI

Yuhao Tang,

Xie Quan, Jie Mei

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 161996 - 161996

Published: March 1, 2025

Language: Английский

Citations

0