Effects of Physical Exercise on the Microbiota in Irritable Bowel Syndrome

Nutrients, Journal Year: 2024, Volume and Issue: 16(16), P. 2657 - 2657

Published: Aug. 11, 2024

Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder characterized by abdominal pain, bloating, diarrhea, and constipation. Recent studies have underscored the significant role of gut microbiota in pathogenesis IBS. Physical exercise, as non-pharmacological intervention, has been proposed to alleviate IBS symptoms modulating microbiota. Aerobic such running, swimming, cycling, shown enhance diversity abundance beneficial bacteria, including Lactobacillus Bifidobacterium. These bacteria produce short-chain fatty acids that possess anti-inflammatory properties support barrier integrity. Studies involving patients participating structured aerobic exercise programs reported improvements their microbiota's composition diversity, alongside an alleviation like pain bloating. Additionally, positively influences mental health reducing stress improving mood, which can further relieve via gut-brain axis. Long-term interventions provide sustained benefits, maintaining stability, supporting immune functions, systemic inflammation. However, must be tailored individual needs avoid exacerbating symptoms. Personalized plans starting with low-to-moderate intensity gradually increasing maximize benefits minimize risks. This review examines impact various types intensities physical on patients, highlighting need for explore optimal protocols. Future research should include larger sample sizes, longer follow-up periods, examine synergistic effects other lifestyle modifications. Integrating into comprehensive management symptom control improve patients' quality life.

Language: Английский

---

Exploring the Prebiotic Potentials of Hydrolyzed Pectins: Mechanisms of Action and Gut Microbiota Modulation

Nutrients, Journal Year: 2024, Volume and Issue: 16(21), P. 3689 - 3689

Published: Oct. 29, 2024

The intestinal microbiota is a complex ecosystem where the microbial community (including bacteria) can metabolize available substrates via metabolic pathways specific to each species, often related in symbiotic relations. As consequence of using and growth, beneficial metabolites be produced. When this reflects health benefits for host, these categorized as prebiotics. Given that most prebiotic candidates must have low molecular weight further metabolized by microbiota, role preliminary biological pretreatment crucial. To provide proper strategy could decrease complexity polysaccharides reduce levels polymerization target molecules, driving better solubilization consequent use bacteria. high pectin degraded (partially depolymerized), its solubility increases, thereby improving utilization gut microbiota. With regards application, prebiotics well-documented advantages when applied food additives, they improve enhance drug effects, all shown vitro, vivo, clinical trials. In review, we aim systematic evidence mechanisms action modulation pectin-derived oligosaccharides produced decreasing overall after physical and/or chemical treatments compare with other types

Language: Английский

---

The physicochemical properties of low molecular weight ‘Chachi’ (Citrus reticulata ‘Chachi’) pectins prepared by different modification methods and their modulation effects on the human gut microbiota

Food Hydrocolloids, Journal Year: 2025, Volume and Issue: unknown, P. 111350 - 111350

Published: March 1, 2025

Language: Английский

---

Role of gut microbiota in thalassemia: a review of therapeutic prospects

Frontiers in Physiology, Journal Year: 2025, Volume and Issue: 16

Published: March 19, 2025

In recent years, the study of gut microbiota has gradually become a research hotspot in field medicine, as dysbiosis is closely related to various diseases. Thalassemia, hereditary hemoglobinopathy, complex pathophysiological mechanism, and traditional treatment methods show limited efficacy. With deeper understanding microbiome, researchers have begun focus on its role pathogenesis thalassemia therapeutic effects. This article aims review potential prospects, analyze latest findings, explore impact mechanisms patients with thalassemia, goal providing new ideas directions for future clinical thalassemia.

Language: Английский

---

Associating structural characteristics to immunomodulating properties of carrot rhamnogalacturonan-I fractions

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 347, P. 122730 - 122730

Published: Sept. 10, 2024

Language: Английский

---