Natural anticancer agents: prospection of medicinal and aromatic plants in modern chemoprevention and chemotherapy DOI Creative Commons
Patricia Quintero-Rincón, Karina Caballero-Gallardo, Jesús Olivero‐Verbel

et al.

Natural Products and Bioprospecting, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 21, 2025

Abstract Natural products obtained from medicinal and aromatic plants are increasingly recognized as promising anticancer agents due to their structural richness, including terpene flavonoid molecules, which induce apoptosis modulate gene expression. These compounds offer an alternative conventional treatments, often costly, face challenges such multidrug resistance. This review aims provide a approach effectively control cancer by consolidating significant findings in identifying natural agent development plants. It synthesizes the of comprehensive search academic databases, PubMed Springer, prioritizing articles published peer-reviewed journals that address bioprospecting agents. The addresses activities plant extracts essential oils, were selected for relevance chemoprevention chemotherapy. Compounds successfully used therapy include Docetaxel (an antimitotic agent), Etoposide VP-16 topoisomerase II inhibitor), Topotecan (a I Thymoquinone Reactive Oxygen Species-ROS inducer), Phenethyl isothiocyanate (with multiple mechanisms). highlights Hinokitiol, Mahanine, Hesperetin, Borneol, Carvacrol, Eugenol, Epigallocatechin gallate, Capsaicin demonstrated efficacy against types, breast, cervical, gastric, colorectal, pancreatic, lung, prostate, skin cancer. Finally, it need continued studies identify novel can be modern Graphical

Language: Английский

A Biocompatible β-Cyclodextrin Inclusion Complex Containing Natural Extracts: A Promising Antibiofilm Agent DOI Creative Commons
Obaydah Abd Alkader Alabrahim, Mostafa Fytory,

Ahmed M. Abou‐Shanab

et al.

Nanoscale Advances, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Biofilms still pose a significant healthcare challenge, worldwide. βCD nanoparticles loaded with Boswellia sacra essential oils (BOS) hold promise for effectively preventing and disrupting bacterial biofilms.

Language: Английский

Citations

0
Preparation of a nanoemulsion from clove oil extract containing phenol and studying its effect on a human MCF-7 breast cancer cell line DOI

Zainab A. Fadhil,

Eman Shaapan Abdelaziz Amin,

Shireen Mohammed Mahmood

et al.

Salud Ciencia y Tecnología, Journal Year: 2025, Volume and Issue: 5, P. 1535 - 1535

Published: April 11, 2025

Breast cancer is one of the major health concerns worldwide. Approximately 2.26 million cases this disease were reported globally in 2020, making it most dangerous type cancer. In previous studies, they linked ifosfamide with clove oil based on a nanoemulsion and studied its cytotoxicity. Our research integrating phenol compound characterized by insolubility water, which limits biological uses, considered an antioxidant, that contains high percentage antioxidants eugenol. By combining two system, we successfully prepared confirming composition using FTSEM, FTIR, UV tests. From perspective, surfaces can effectively absorb droplets to achieve more efficient activities. We then calculated encapsulation efficiency, was very high. Subsequently, different concentrations used MTT method test effect human breast cell lines verified cytotoxicity survival rates for each concentration. extracted IC50 value found phenolic killed cells increase

Language: Английский

Citations

0
Natural anticancer agents: prospection of medicinal and aromatic plants in modern chemoprevention and chemotherapy DOI Creative Commons
Patricia Quintero-Rincón, Karina Caballero-Gallardo, Jesús Olivero‐Verbel

et al.

Natural Products and Bioprospecting, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 21, 2025

Abstract Natural products obtained from medicinal and aromatic plants are increasingly recognized as promising anticancer agents due to their structural richness, including terpene flavonoid molecules, which induce apoptosis modulate gene expression. These compounds offer an alternative conventional treatments, often costly, face challenges such multidrug resistance. This review aims provide a approach effectively control cancer by consolidating significant findings in identifying natural agent development plants. It synthesizes the of comprehensive search academic databases, PubMed Springer, prioritizing articles published peer-reviewed journals that address bioprospecting agents. The addresses activities plant extracts essential oils, were selected for relevance chemoprevention chemotherapy. Compounds successfully used therapy include Docetaxel (an antimitotic agent), Etoposide VP-16 topoisomerase II inhibitor), Topotecan (a I Thymoquinone Reactive Oxygen Species-ROS inducer), Phenethyl isothiocyanate (with multiple mechanisms). highlights Hinokitiol, Mahanine, Hesperetin, Borneol, Carvacrol, Eugenol, Epigallocatechin gallate, Capsaicin demonstrated efficacy against types, breast, cervical, gastric, colorectal, pancreatic, lung, prostate, skin cancer. Finally, it need continued studies identify novel can be modern Graphical

Language: Английский

Citations

0