Journal of Materials Chemistry B,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
This
review
discusses
the
recent
developments
in
copper-based
nanomaterials
that
utilize
copper-induced
cell
death,
categorized
by
materials
systems,
while
highlighting
limitations
of
current
cuproptosis
related
nanomaterials.
Journal of Materials Chemistry B,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Photothermal
therapy
(PTT)
is
a
cutting-edge
technique
that
harnesses
light
energy
and
converts
it
into
heat
for
precise
tumor
ablation.
By
employing
photothermal
agents
to
selectively
generate
target
cancer
cells,
PTT
has
emerged
as
promising
treatment
strategy.
Notably,
therapies
conducted
in
the
second
near-infrared
(NIR-II)
window
exhibit
superior
therapeutic
outcomes,
owing
deeper
tissue
penetration
reduced
scattering.
In
this
study,
we
developed
biomimetic
NIR-II
aggregation-induced
emission
(AIE)
nanoparticles
(2TB-NPs@TM)
high-efficiency
imaging
targeted
phototherapy
of
ovarian
cancer.
The
core
nanoparticle
aggregates
(2TB-NPs)
display
strong
fluorescence
high
conversion
efficiency,
while
outer
cell
membrane
coating
facilitates
active
targeting
recognition
tissues.
This
design
imparts
excellent
biocompatibility
enhances
drug
delivery
leading
potent
synergistic
effects.
Our
findings
open
new
avenues
advancing
targeted,
high-performance
diagnostics
treatment.
Abstract
Gastrointestinal
cancers,
a
major
global
cause
of
cancer‐related
mortality
and
disease
burden,
are
heterogeneous
group
malignant
aliments
involving
different
organs
the
digestive
system.
The
late
clinical
diagnosis,
genomic
tumor
heterogeneity,
high
complexity
gastrointestinal
microenvironment,
along
with
increasing
treatment
resistance
have
been
recognized
as
main
contributing
factors
to
current
inadequacy
interventions
poor
prognosis
cancer
patients.
In
coming
years,
is
unfortunately
predicted
increase
due
absence
early
detection
effective
therapeutic
options.
Biomembrane‐coated
biomimetic
nanoparticles
(NPs)
recently
appointed
advanced
nanotechnological
tools
for
management
cancers.
These
comprise
not
only
cell‐mimicking
nanodevices
(the
pioneers
this
top‐down
coating
technology),
but
also
exosome
bacterial
mimetics.
Due
their
enhanced
bio‐interfacing
features,
biocompatibility,
immune
evasion,
specific
targetability
tumorous
tissues,
these
nanostructures
successfully
exploited
provide
safer,
effective,
targeted
applications.
This
review
highlights
latest
research
on
biomembrane‐coated
nanosystems
therapy
diagnosis
most
common
deadliest
subtypes
namely
colorectal
cancer,
gastric
liver
esophageal
pancreatic
cancer.
challenges
toward
translation
mentioned.
Journal of Nanobiotechnology,
Journal Year:
2025,
Volume and Issue:
23(1)
Published: March 12, 2025
While
radiotherapy-induced
immunogenic
cell
death
(ICD)
holds
potential
for
enhancing
cancer
immunotherapy,
the
conventional
high-dose
irradiation
often
leads
to
an
immunosuppressive
microenvironment
and
systemic
toxicity.
Therefore,
a
biomimetic
nanoplatform
membrane
coated-nitrogen-doped
graphene
quantum
dots
combined
with
Au
nanoparticles
(C-GAP)
was
developed
in
this
study.
Firstly,
homologous
traceable
targeting
features
of
C-GAP
enables
tumor-selective
accumulation,
providing
reference
selection
timing
radiotherapy.
Secondly,
radiosensitization
by
Low-dose
(LDI)
amplifies
reactive
oxygen
species
(ROS)
generation
trigger
potent
ICD.
Thirdly,
remarkable
immune
remodeling
induced
enhances
CD8+
T
infiltration
effector
function.
Single-cell
RNA
sequencing
revealed
that
C-GAP-LDI
combination
upregulates
TNF
CCL
signaling
pathway
expression
tumor-infiltrating
cells
which
potentiates
tumor
eradication.
Our
findings
present
novel
approach
safe
effective
radioimmunotherapy,
where
sensitized
LDI
achieves
therapeutic
enhancement
through
precise
ICD
induction
activation.
Chemical Product and Process Modeling,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 8, 2025
Abstract
This
article
studies
the
application
of
biomimetic
triangular
non-smooth
surface
materials
in
automotive
acoustic
packaging
and
their
effects
on
sound
absorption
insulation
performance.
Firstly,
Statistical
Energy
Analysis
(SEA)
predicting
high-frequency
vibration
noise
automobiles
was
discussed.
Due
to
limitations
finite
element
method
noise,
SEA
has
gradually
been
widely
applied
continuously
improved
domestic
foreign
research.
establishes
models
for
front
panel
floor.
It
analyzes
performance
different
through
simulation,
focusing
materials.
The
experimental
results
show
that
material
with
a
three-layer
structure
excellent
range.
Specifically,
cowl
floor
adopts
composed
organic
fiber,
molded
felt,
polyurethane
foam
felt.
simulation
PU
bionic
wedge
coefficient
0.983
at
1,000
Hz,
significantly
better
than
traditional
smooth
material.
In
addition,
increased
by
2.9
dB
48.1
dB,
respectively,
5,000
Hz.
