Pathology - Research and Practice, Journal Year: 2024, Volume and Issue: 266, P. 155747 - 155747
Published: Nov. 28, 2024
Language: Английский
ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 12, 2025
As we progress into the 21st century, cancer stands as one of most dreaded diseases. With approximately in every four individuals facing a lifetime risk developing cancer, remains serious health challenges worldwide. Its multifaceted nature makes it an arduous and tricky problem to diagnose treat. Over years, researchers have explored plenty approaches avenues improve management. One notable strategy includes study extracellular vesicles (EVs) potential biomarkers therapeutics. Among these EVs, exosomes emerged particularly promising candidates due their unique characteristic properties functions. They are small membrane-bound secreted by cells carrying cargo biomolecules such proteins, nucleic acids, lipids. These play crucial roles intercellular communication, facilitating transfer biological information between cell-to-cell communication. Exosomes transport cargoes DNA, RNA, lipids involved cellular reprogramming promoting cancer. In this review, explore molecular composition exosomes, significance chemistry development, its theranostic application well research complications solutions.
Language: Английский
Citations
1
Results in Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 102177 - 102177
Published: March 1, 2025
Language: Английский
Citations
1
Cancers, Journal Year: 2025, Volume and Issue: 17(6), P. 940 - 940
Published: March 10, 2025
Exosomes have emerged as pivotal players in precision oncology, offering innovative solutions to longstanding challenges such metastasis, therapeutic resistance, and immune evasion. These nanoscale extracellular vesicles facilitate intercellular communication by transferring bioactive molecules that mirror the biological state of their parent cells, positioning them transformative tools for cancer diagnostics therapeutics. Recent advancements exosome engineering, artificial intelligence (AI)-driven analytics, isolation technologies are breaking barriers scalability, reproducibility, clinical application. Bioengineered exosomes being leveraged CRISPR-Cas9 delivery, while AI models enhancing biomarker discovery liquid biopsy accuracy. Despite these advancements, key obstacles heterogeneity populations lack standardized protocols persist. This review synthesizes pioneering research on biology, molecular translation, emphasizing dual roles both mediators tumor progression intervention. It also explores emerging areas, including microbiome–exosome interactions integration machine learning exosome-based medicine. By bridging innovation with translational strategies, this work charts a forward-looking path integrating into next-generation care, setting it apart comprehensive guide overcoming technological hurdles rapidly evolving field.
Language: Английский
Citations
0
Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown
Published: March 28, 2025
Language: Английский
Citations
0
Pathology - Research and Practice, Journal Year: 2025, Volume and Issue: unknown, P. 155950 - 155950
Published: March 1, 2025
Language: Английский
Citations
0
Clinical and Experimental Medicine, Journal Year: 2025, Volume and Issue: 25(1)
Published: April 24, 2025
Language: Английский
Citations
0
Molecular Biology Reports, Journal Year: 2025, Volume and Issue: 52(1)
Published: April 24, 2025
Language: Английский
Citations
0
Sustainable Food Technology, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Fruit exosomes are the source of natural cancer therapeutic tools.
Language: Английский
Citations
2
Pathology - Research and Practice, Journal Year: 2024, Volume and Issue: 266, P. 155747 - 155747
Published: Nov. 28, 2024
Language: Английский
Citations
0