Biomedical Applications of Metal–Organic Frameworks Revisited
Industrial & Engineering Chemistry Research,
Journal Year:
2025,
Volume and Issue:
64(4), P. 1907 - 1932
Published: Jan. 14, 2025
Metal–organic
frameworks
(MOFs)
have
been
shown
to
be
great
alternatives
traditional
porous
materials
in
various
chemical
applications,
and
they
very
widely
studied
for
biomedical
applications
the
past
decade
specifically
drug
storage.
After
our
review
published
2011
[Keskin
Kızılel,
Ind.
Eng.
Chem.
Res.
2011,
50
(4),
1799–1812,
10.1021/ie101312k],
we
witnessed
a
fast
growth
not
only
number
variety
of
MOFs
but
also
their
usage
across
broad
spectrum
fields.
With
recent
integration
molecular
modeling
data
science
approaches
experimental
studies,
significantly
accelerated
positioning
them
as
pivotal
components
regenerative
medicine,
medical
imaging,
diagnostics.
In
this
review,
visited
diverse
considering
computational
efforts
on
storage
delivery,
bioimaging,
biosensing.
We
focused
underlying
mechanisms
governing
interactions
between
biological
systems
discussed
both
opportunities
challenges
field
highlight
potential
advanced
therapeutics
cancer
neurological
diseases.
Language: Английский
Metal-organic framework-based materials: From synthesis and characterization routes to electrochemical sensing applications
Coordination Chemistry Reviews,
Journal Year:
2025,
Volume and Issue:
536, P. 216680 - 216680
Published: April 10, 2025
Language: Английский
Weaving the gates of life: Pioneering a new era in oral gene delivery with metal-organic frameworks
Chemical Engineering Journal,
Journal Year:
2024,
Volume and Issue:
503, P. 158522 - 158522
Published: Dec. 10, 2024
Language: Английский
Climate friendly MOFs synthesis for drug delivery systems by integrating AI, intelligent manufacturing, and quantum solutions in industry 6.0 sustainable approach
Toxicology Research,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Dec. 31, 2024
Abstract
Since
the
Industrial
Revolution,
ecological
damage,
ecosystem
disruption,
and
climate
change
acceleration
have
frequently
resulted
from
human
advancement
at
price
of
environment.
Due
to
rise
in
illnesses,
Industry
6.0
calls
for
a
renewed
dedication
sustainability
with
latest
technologies.
Focused
research
creative
solutions
are
needed
achieve
UN
Sustainable
Development
Goals
(SDGs),
especially
3,
9,
13,
14,
15,
17.
A
promising
sustainable
technology
enhancing
healthcare
while
reducing
environmental
effect
is
Metal
Organic
Frameworks
(MOFs).
MOFs
perfect
drug
administration
because
their
high
surface
areas,
adjustable
pore
sizes,
remarkable
drug-loading
capacities.
They
created
by
combining
advanced
artificial
intelligence,
intelligent
manufacturing,
quantum
computing.
Researchers
can
create
functional
groups
or
ligands
that
bind
selectively
target
cells
tissues,
minimizing
off-target
effects,
thanks
distinct
benefits
families
like
MIL,
HKUST,
UiO,
ZIF
etc.
offer
targeted
delivery.
Combining
other
nanomaterials
results
multipurpose
systems
handle
challenging
biomedical
issues.
Despite
its
promise,
there
still
issues
MOFs’
possible
toxicity
long-term
stability
physiological
settings.
To
advance
medicinal
applications,
these
problems
must
be
resolved.
increase
usefulness
medicine
critically
analysing
limitations
putting
up
alternatives.
The
creation
technologies
(additive
manufacturing
etc.)
delivery
prime
example
how
scientific
stewardship
may
coexist
provide
advantageous
both
people
Language: Английский