Microplastics and Nanoplastics in Atheromas and Cardiovascular Events

New England Journal of Medicine, Journal Year: 2024, Volume and Issue: 390(10), P. 900 - 910

Published: March 6, 2024

Microplastics and nanoplastics (MNPs) are emerging as a potential risk factor for cardiovascular disease in preclinical studies. Direct evidence that this extends to humans is lacking.

Language: Английский

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Particulate Matter Air Pollution is a Significant Risk Factor for Cardiovascular Disease

Current Problems in Cardiology, Journal Year: 2023, Volume and Issue: 49(1), P. 102094 - 102094

Published: Sept. 19, 2023

Language: Английский

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Air pollution exposure and cardiometabolic risk

The Lancet Diabetes & Endocrinology, Journal Year: 2024, Volume and Issue: 12(3), P. 196 - 208

Published: Feb. 2, 2024

Language: Английский

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Toward cleaner air and better health: Current state, challenges, and priorities

Science, Journal Year: 2024, Volume and Issue: 385(6707), P. 386 - 390

Published: July 25, 2024

The most up-to-date estimate of the global burden disease indicates that ambient air pollution, including fine particulate matter and ozone, contributes to an estimated 5.2 million deaths each year. In this review, we highlight challenges in estimating population exposure pollution attributable health risks, particularly low- middle-income countries among vulnerable populations. To protect public health, evidence so far confirms urgent needs prioritize interdisciplinary research on risk assessment develop evidence-based intervention policies communication strategies. Here, synthesize emerging supporting monitoring evaluation progress implementation Global Air Quality Guidelines prepared by World Health Organization.

Language: Английский

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Equity concerns in transformative planning: Barcelona’s Superblocks under scrutiny

Cities & Health, Journal Year: 2023, Volume and Issue: 7(6), P. 950 - 958

Published: May 26, 2023

RESUMENLa planificación transformadora reestructura radicalmente los usos del suelo urbano, diseños y paisajes urbanos para responder al cambio climático mejorar la salud calidad de vida ciudadanía. Examinamos cómo puede perder vista a cuestiones relacionadas con equidad, apoyándonos en el ejemplo plan transformador Barcelona implementar Supermanzanas (Superblocks in English, Superilles Catalan). Argumentamos que las preguntas sobre equidad distributiva relacional, incluida evaluación priorización necesidades impulsadas por interseccional; beneficios o cargas locales espacializados; objetivos justicia movilidad; exclusión gentrificación verde, junto procesal, deben ocupar un lugar destacado agenda lograr urbana verdadera. También pueden implicar trade-offs claves entre abordar vulnerabilidades sociales ambientales.

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Toward Heart-Healthy and Sustainable Cities: A Policy Statement From the American Heart Association

Circulation, Journal Year: 2024, Volume and Issue: 149(15)

Published: March 4, 2024

Nearly 56% of the global population lives in cities, with this number expected to increase 6.6 billion or >70% world's by 2050. Given that cardiometabolic diseases are leading causes morbidity and mortality people living urban areas, transforming cities provisioning systems (or systems) toward health, equity, economic productivity can enable dual attainment climate health goals. Seven provide food, energy, mobility-connectivity, housing, green infrastructure, water management, waste management lie at core human well-being, sustainability. These transcend city boundaries (eg, demand for water, energy is met transboundary supply); thus, entire system a larger construct than local environments. Poorly designed starkly evident worldwide, resulting unprecedented exposures adverse risk factors, including limited physical activity, lack access heart-healthy diets, reduced greenery beneficial social interactions. Transforming health-first approach could be accomplished through integrated spatial planning, along addressing current gaps key systems. Such an will help mitigate undesirable environmental improve cardiovascular metabolic while improving planetary health. The purposes American Heart Association policy statement present conceptual framework, summarize evidence base, outline principles heart-health sustainability outcomes.

Language: Английский

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Disparities in air pollution attributable mortality in the US population by race/ethnicity and sociodemographic factors

Nature Medicine, Journal Year: 2024, Volume and Issue: 30(10), P. 2821 - 2829

Published: July 1, 2024

Language: Английский

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Association of Environmental Injustice and Cardiovascular Diseases and Risk Factors in the United States

Journal of the American Heart Association, Journal Year: 2024, Volume and Issue: 13(7)

Published: March 27, 2024

Background While the impacts of social and environmental exposure on cardiovascular risks are often reported individually, combined effect is poorly understood. Methods Results Using 2022 Environmental Justice Index, socio‐environmental justice index burden module ranks census tracts were divided into quartiles (quartile 1, least vulnerable tracts; quartile 4, most tracts). Age‐adjusted rate ratios (RRs) coronary artery disease, strokes, various health measures in Prevention Population‐Level Analysis Community Estimates data compared between using multivariable Poisson regression. The 4 Index was associated with a higher disease (RR, 1.684 [95% CI, 1.660–1.708]) stroke 2.112 2.078–2.147]) 1 Index. Similarly, 1.057 CI,1.043‐1.0716] 1.118 1.102–1.135]) significantly than module. Similar results observed for chronic kidney hypertension, diabetes, obesity, high cholesterol, lack insurance, sleep <7 hours per night, no leisure time physical activity, impaired mental >14 days. Conclusions prevalence CVD its risk factors highly increased adversities, plays an important role independent factors.

Language: Английский

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Assessing Adverse Health Effects of Long-Term Exposure to Low Levels of Ambient Air Pollution: The HEI Experience and What’s Next?

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(29), P. 12767 - 12783

Published: July 11, 2024

Although concentrations of ambient air pollution continue to decline in high-income regions, epidemiological studies document adverse health effects at levels below current standards many countries. The Health Effects Institute (HEI) recently completed a comprehensive research initiative investigate the long-term exposure low United States (U.S.), Canada, and Europe. We provide an overview synthesis results this along with other key research, strengths limitations remaining needs. three funded through HEI estimated fine particulate matter (PM2.5), nitrogen dioxide, ozone, pollutants on broad range outcomes, including cause-specific mortality cardiovascular respiratory morbidity. To ensure high quality comparability across studies, worked actively study teams engaged independent expert panels for project oversight review. All documented positive associations between PM2.5 U.S. National Ambient Air Quality Standards proposed European Union limit values. Furthermore, observed nonthreshold linear or supra-linear (Canada Europe) exposure-response functions mortality. Heterogeneity was found both magnitude shape association within studies. Strengths included large populations (7–69 million), state-of-the-art assessment methods, thorough statistical analyses that applied novel methods. Future work is needed better understand potential sources heterogeneity findings regions. Other areas future include changing evolving nature PM components sources, wildfires, role indoor environments. This provided important new evidence exposures standards, suggesting further reductions could yield larger benefits than previously anticipated.

Language: Английский

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Spatial Heterogeneity of the Respiratory Health Impacts of Wildfire Smoke PM_2.5 in California

GeoHealth, Journal Year: 2024, Volume and Issue: 8(4)

Published: March 28, 2024

Abstract Wildfire smoke fine particles (PM 2.5 ) are a growing public health threat as wildfire events become more common and intense under climate change, especially in the Western United States. Studies assessing association between PM exposure typically summarize effects over study area. However, responses to may vary spatially. We evaluated spatially‐varying respiratory acute care utilization risks associated with short‐term explored community characteristics possibly driving spatial heterogeneity. Using ensemble‐modeled daily , we defined day have wildfire‐specific concentration ≥15 μg/m 3 . included emergency department visits unplanned hospitalizations 1,396 California ZIP Code Tabulation Areas (ZCTAs) 15 census‐derived characteristics. Employing case‐crossover design conditional logistic regression, observed increased odds of on days at state level (odds ratio [OR] = 1.06, 95% confidence interval [CI]: 1.05, 1.07). Across air basins, ORs ranged from 0.88 1.57, highest effect estimate San Diego. A within‐community matching Bayesian hierarchical model also revealed heterogeneity ZCTA‐level rate differences. For example, communities higher percentage Black or Pacific Islander residents had stronger ‐outcome relationships, while conditioning tree canopy attenuated associations. found an important smoke‐related impacts across counties, ZCTAs, identified vulnerable communities, providing evidence guide policy development resource allocation.

Language: Английский

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