International Journal of Mechanical Sciences, Journal Year: 2023, Volume and Issue: 265, P. 108861 - 108861
Published: Nov. 10, 2023
Language: Английский
Journal of Water Process Engineering, Journal Year: 2024, Volume and Issue: 63, P. 105470 - 105470
Published: May 25, 2024
Language: Английский
Citations
20
Environmental Research, Journal Year: 2023, Volume and Issue: 233, P. 116455 - 116455
Published: June 24, 2023
Language: Английский
Citations
26
Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)
Published: Oct. 12, 2024
Endothelial cells (ECs) are pivotal in maintaining vascular health, regulating hemodynamics, and modulating inflammatory responses. Nanocarriers hold transformative potential for precise drug delivery within the system, particularly targeting ECs therapeutic purposes. However, complex interactions between nanocarriers present significant challenges development clinical translation of nanotherapeutics. This review assesses recent advancements key strategies employing to ECs. It suggested that through physicochemical design surface modifications, can enhance specificity improve internalization efficiency Additionally, we elaborated on applications specifically designed treatment cardiovascular diseases, cancer metastasis, disorders. Despite these advancements, safety concerns, complexity vivo processes, challenge achieving subcellular remain obstacles effective with nanocarriers. A comprehensive understanding endothelial cell biology its interaction is crucial realizing full targeted systems.
Language: Английский
Citations
9
Physics of Fluids, Journal Year: 2024, Volume and Issue: 36(8)
Published: Aug. 1, 2024
In this work, we experimentally studied bubble formation on the superhydrophobic surface (SHS) under a constant gas flow rate and at quasi-static regime. SHS with radius RSHS ranging from 4.2 to 19.0 mm was used. We observed two bubbling modes A B, depending RSHS. mode for small RSHS, contact line fixed rim of SHS, angle (θ) initially reduced, then maintained as constant, finally increased. B large continuously expanded, θ slowly reduced. For both modes, during necking, retracts, close equilibrium angle. Moreover, pinch-off early stage similar nozzle followed power-law relation Rneck ∼ τ0.54, where is minimum neck τ time detaching. Furthermore, calculated forces acting found balance between one lifting force (pressure force) retaining (surface tension buoyancy force). Last, waiting finite volume be detected The detached well predicted by Tate volume, which derived based function base radius.
Language: Английский
Citations
4
Physics of Fluids, Journal Year: 2025, Volume and Issue: 37(1)
Published: Jan. 1, 2025
This paper investigates the dynamics of an encapsulated bubble within a spherical liquid cell that is surrounded by infinite elastic solid, aiming to enhance our understanding oscillations, which crucial for targeted therapeutic release. The Carreau–Yasuda model used surrounding liquid, and nonlinear neo–Hookean hyperelastic shell, replacing simpler Newtonian linear shell models. increased complexity necessary accurately capture oscillations in parameter range where both non-Newtonian properties behavior are critical. Resonance occurs when acoustic field's driving frequency matches natural frequency, thus, amplifying oscillations. solid can dampen or amplify these depending on their magnitudes resonance making it essential optimize balanced control responsiveness parametric surface area wall shear stress determined safe biomedical application. maximum 4000 μm2 3000 Pa parameters given this paper. study also highlights damping effect power-law index varies with ultrasonic drive pressure amplitude, properties, cavity size, not observed fluids.
Language: Английский
Citations
0
Physics of Fluids, Journal Year: 2025, Volume and Issue: 37(2)
Published: Feb. 1, 2025
The nonlinear volume oscillations and shape deformation of a gas bubble in water driven by spatially uniform, time-dependent dual frequency acoustic source is considered. Employing model that includes mode interactions to third order, the respective, distinct values driving pressure are chosen order parametrically excite two different axisymmetric modes via fundamental resonance. It shown develop on timescales with their relative growth rates controlling resultant dynamics. For suitably strengths, intermediate steady state observed. In particular, for cases where higher grows fastest subsequently saturates first, then dominated this observed finite time. However, as lower grows, decays if saturates, mode, indicating preferential oscillation state. similar timescales, balance between strengths results either growing unbounded or one suppressing parametric other mode.
Language: Английский
Citations
0
Engineering Analysis with Boundary Elements, Journal Year: 2024, Volume and Issue: 160, P. 76 - 88
Published: Jan. 4, 2024
Language: Английский
Citations
2
The European Physical Journal Special Topics, Journal Year: 2024, Volume and Issue: 233(8-9), P. 1625 - 1635
Published: April 29, 2024
Abstract The onset of non-spherical oscillations a microbubble in an unbounded power–law liquid, important for biomedical ultrasound applications, is studied. Two sets evolution equations are obtained from the equation motion: Rayleigh Plesset-type spherical and oscillations. modeled using perturbation method via Legendre polynomials. kinds instabilities, namely parametric Rayleigh-Taylor investigated. A higher index causes damping both effect depends on ultrasonic drive frequency. At natural frequency, amplitude perturbations high compared to non-resonant cases. low consistency index, decreases. Unlike Newtonian liquids, viscosity liquids affected by frequency acoustic field, thereby affecting instability.
Language: Английский
Citations
2
Advanced NanoBiomed Research, Journal Year: 2024, Volume and Issue: unknown
Published: June 20, 2024
Ultrasound can activate nano/microparticles to induce reactive oxygen species (ROS). The advantages of deep penetration and precise spatiotemporal control are demonstrated for multiple applications, such as sonodynamic therapy, chemical industry, environmental treatment. Meanwhile, a toolbox inorganic particles is developed enhance ROS production via cavitation enhancement, sonoluminescence, piezocatalytic effect. Nonetheless, sophisticated influences ultrasonic parameters hamper further exploration novel sonosensitized materials. In this perspective, the influential in different mechanisms reviewed, emphasizing relationship between ultrasound frequency catalytic activity, outlooks provided on study sonosensitizers.
Language: Английский
Citations
2
The Journal of the Acoustical Society of America, Journal Year: 2024, Volume and Issue: 156(1), P. 55 - 64
Published: July 1, 2024
The existence of finite amplitude shape distortion caused by parametrically excited surface instabilities for a gas bubble in water driven temporally periodic, spatially uniform pressure field an axisymmetric geometry is investigated. Employing nonlinear coupled system equations which includes mode interactions to third order, the resultant spherical oscillations, translation, and are modelled, placing no restriction on size oscillations. model accounts viscous thermal damping with compressibility effects. synchronous higher order induced sustained, amplitude, periodic deformation demonstrated. excitement odd via mechanism shown give rise linear self-propulsion. For larger driving amplitudes, it that more than one can be at same frequency but different resonance mechanisms, leading involved increased possibility
Language: Английский
Citations
2