Molecular signatures of biomacromolecules at micron and submicron scales in Arctica islandica shells DOI Creative Commons
Oluwatoosin B. A. Agbaje, Qian Huang, Michiel Op De Beeck

et al.

Chemical Geology, Journal Year: 2024, Volume and Issue: 673, P. 122550 - 122550

Published: Dec. 7, 2024

Language: Английский

Unveiling Hidden Threats: Introduction of a Routine Workflow for Label-Free and Non- destructive Detection of Microplastics in Human FFPE Tissue Sections DOI Open Access
Elisabeth S. Gruber,

Verena Karl,

Kristina Duswald

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 10, 2025

ABSTRACT Microplastic (MP) pollution has emerged as a significant environmental and health concern. This study aimed at developing novel method for detecting MP particles in deparaffinized formalin-fixed paraffin-embedded (FFPE) routine tissue sections of human colon samples. By utilizing mid-infrared photothermal (MIP) microscopy, also known optical infrared (OPTIR) spectroscopy, we here to establish work-flow representing non-destructive spectroscopic approach distinct identification localization polymers FFPE by respecting standardized protocols well integrated into clinical routine. After OPTIR analysis, samples were processed H&E staining histopathological analysis defined regions interest. using succeeded localizing polyethylene (PE), polystyrene (PS), terephthalate (PET) MPs interest (21 PE particles, 1 PS particle, PET fiber) clearly identifying the embedded respective sections. Subsequent confirmed characteristic features inflammation spatially associated with polymers. We present first time diagnostic workflow that potential enhance our understanding accumulation organ slides allows exploration its implications health. The observed morphological proximity identified could possibly indicate link between exposure inflammation.

Language: Английский

Citations

0

Bioorthogonal Raman and IR probes for live cell metabolomics: a library DOI Creative Commons
Wiktoria Korona, B. Orzechowska, Kacper Siąkała

et al.

Sensors and Actuators B Chemical, Journal Year: 2025, Volume and Issue: unknown, P. 137363 - 137363

Published: Jan. 1, 2025

Language: Английский

Citations

0

Fast Detection and Classification of Microplastics by a Wide-Field Fourier Transform Raman Microscope DOI Creative Commons
Benedetto Ardini, Lucia Pittura, Andrea Frontini

et al.

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

A number of applications require methods to detect with high spatial resolution and chemical specificity microplastics (MPs) extracted from different matrices. Here we introduce a wide-field hyperspectral Fourier transform Raman microscope for the rapid detection identification MPs. The instrument, based on common-path birefringent interferometer, combines (∼1 μm) spectral (∼23 cm-1) fast measurement times (∼15 min 100 kpixel image) enables suppression sample fluorescence by proper choice scan interval interferometer. After validating instrument MPs commercial origin, demonstrate its ability matrices, filtering seawater pretreated gastrointestinal tracts fish, analyzing concentrated onto filters. We expect that our will enable high-quality, cost-effective, MPs, fulfilling also requirements large-scale monitoring plans environmental

Language: Английский

Citations

0

High-resolution infrared imaging performance of new high numerical aperture Schwarzschild objectives DOI
Karolina Kadela,

Honorata Oleś,

Karolina Kosowska

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2025, Volume and Issue: 331, P. 125769 - 125769

Published: Jan. 20, 2025

Language: Английский

Citations

0

Microplastic distribution and its implications for human health through marine environments DOI

C. M. Ho,

Weiying Feng, Xiaofeng Li

et al.

Journal of Environmental Management, Journal Year: 2025, Volume and Issue: 382, P. 125427 - 125427

Published: April 18, 2025

Language: Английский

Citations

0

Guest editorial: Special topic on mid-IR photonics DOI Creative Commons
A. Fuerbach, Christian Grillet, Konstantin L. Vodopyanov

et al.

APL Photonics, Journal Year: 2025, Volume and Issue: 10(4)

Published: April 1, 2025

Language: Английский

Citations

0

Colocalized Raman and IR Spectroscopies via Vibrational-Encoded Fluorescence for Comprehensive Vibrational Analysis DOI
Zhao‐Dong Meng,

Tairui Wu,

Zhou Li-ling

et al.

Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: unknown

Published: May 2, 2025

Vibrational spectroscopy, including Raman scattering and infrared (IR) absorption, provides essential molecular fingerprint information, facilitating diverse applications, such as interfacial sensing, chemical analysis, biomedical diagnostics. The complementary selection rules of IR spectroscopies offer distinct, yet mutually reinforcing, insights into structure dynamics. However, in dynamic or complex environments, either technique alone is not capable providing a complete nuanced picture vibrations. Simultaneous detection vibrational modes within the same group remains challenging due to wavelength discrepancies sensitivity mismatches between spectroscopies. In this work, address gap these spectroscopies, we developed an integrated approach based on vibrational-encoded fluorescence (VEF), which information respectively encoded different parts radiation: Stokes carrying anti-Stokes reflecting information. This method employs dual-resonant microsphere-on-mirror plasmonic bridge waveband gap, enabling simultaneous visible spectrum with ultrahigh down ∼100 molecules. Hyperspectral colocalization imaging demonstrates spatial correlations By careful calibration, efficiency improved by 8 orders magnitude compared unenhanced spectroscopy. creates new opportunities for precise identification environments.

Language: Английский

Citations

0

Molecular signatures of biomacromolecules at micron and submicron scales in Arctica islandica shells DOI Creative Commons
Oluwatoosin B. A. Agbaje, Qian Huang, Michiel Op De Beeck

et al.

Chemical Geology, Journal Year: 2024, Volume and Issue: 673, P. 122550 - 122550

Published: Dec. 7, 2024

Language: Английский

Citations

0