Experimental evolution in biofilm populations DOI Creative Commons
Hans Steenackers,

Ilse Parijs,

Kevin R. Foster

et al.

FEMS Microbiology Reviews, Journal Year: 2016, Volume and Issue: 40(3), P. 373 - 397

Published: Feb. 18, 2016

Biofilms are a major form of microbial life in which cells dense surface associated communities that can persist for many generations. The long-life biofilm means they be strongly shaped by evolutionary processes. Here, we review the experimental study evolution communities. We first provide an overview different models used to and their advantages disadvantages. then illustrate vast amount diversification observed during evolution, discuss (i) potential ecological processes behind diversification, (ii) recent insights into genetics adaptive (iii) striking degree parallelism between experiments real-life biofilms (iv) consequences diversification. In second part, provided how growth structure promote cooperative phenotypes. Overall, our analysis points important role cooperation bacterial survival productivity. Deeper understanding both is key importance design improved antimicrobial strategies diagnostic techniques.

Language: Английский

The ecology of the microbiome: Networks, competition, and stability DOI
Katharine Z. Coyte, Jonas Schlüter, Kevin R. Foster

et al.

Science, Journal Year: 2015, Volume and Issue: 350(6261), P. 663 - 666

Published: Nov. 5, 2015

What makes the gut microbiome stable? Classically, we think of our as stable, benign, and cooperative. Recent experimental work is beginning to unpick essential functions that can be attributed stable microbiota humans. To able manipulate improve health, need understand community structure composition models quantify predict stability. Coyte et al. applied concepts tools from ecology assembly. Independently developed converged on a surprising answer: A high diversity species likely coexist stably when system dominated by competitive, rather than cooperative, interactions. Science , this issue p. 663

Language: Английский

Citations

2190
Spatial structure, cooperation and competition in biofilms DOI
Carey D. Nadell, Knut Drescher, Kevin R. Foster

et al.

Nature Reviews Microbiology, Journal Year: 2016, Volume and Issue: 14(9), P. 589 - 600

Published: July 25, 2016

Language: Английский

Citations

918
Bacterial siderophores in community and host interactions DOI
Jos Kramer, Özhan Özkaya, Rolf Kümmerli

et al.

Nature Reviews Microbiology, Journal Year: 2019, Volume and Issue: 18(3), P. 152 - 163

Published: Nov. 20, 2019

Language: Английский

Citations

728
The evolution of cooperation within the gut microbiota DOI
Seth Rakoff-Nahoum, Kevin R. Foster,

Laurie E. Comstock

et al.

Nature, Journal Year: 2016, Volume and Issue: 533(7602), P. 255 - 259

Published: April 22, 2016

Language: Английский

Citations

561
Tumorigenesis: it takes a village DOI

Doris P. Tabassum,

Kornélia Polyák

Nature reviews. Cancer, Journal Year: 2015, Volume and Issue: 15(8), P. 473 - 483

Published: July 2, 2015

Language: Английский

Citations

537
Metabolic co-dependence gives rise to collective oscillations within biofilms DOI
Jintao Liu,

Arthur Prindle,

Jacqueline Humphries

et al.

Nature, Journal Year: 2015, Volume and Issue: 523(7562), P. 550 - 554

Published: July 1, 2015

Language: Английский

Citations

443
Ecology and evolution of metabolic cross-feeding interactions in bacteria DOI Creative Commons
Glen G D’Souza, Shraddha Shitut, Daniel Preußger

et al.

Natural Product Reports, Journal Year: 2018, Volume and Issue: 35(5), P. 455 - 488

Published: Jan. 1, 2018

The causes and consequences of bacterial metabolic cross-feeding mutualisms.

Language: Английский

Citations

434
Microbial nutrient niches in the gut DOI Creative Commons
Maria de Fátima Pereira, David Berry

Environmental Microbiology, Journal Year: 2016, Volume and Issue: 19(4), P. 1366 - 1378

Published: Dec. 30, 2016

Summary The composition and function of the mammalian gut microbiota has been subject much research in recent years, but principles underlying assembly structure this complex community remain incompletely understood. Processes that shape are thought to be mostly niche‐driven, with environmental factors such as available nutrients largely determining whether or not an organism can establish. concept nutrient landscape dictates which organisms successfully colonize persist was first proposed Rolf Freter's niche theory. In a situation where perfectly mixed there is balanced microbial growth, Freter postulated only survive if it able utilize one few limiting more efficiently than its competitors. Recent experimental work indicates, however, vary space time. We propose scenario, theory must expanded account for co‐existence microorganisms utilizing same distinct sites at different times, metabolic flexibility mixed‐substrate utilization common strategies survival face ever‐present fluctuations.

Language: Английский

Citations

309
Biofilm Formation As a Response to Ecological Competition DOI Creative Commons
Nuno M. Oliveira, Esteban Martínez‐García, João B. Xavier

et al.

PLoS Biology, Journal Year: 2015, Volume and Issue: 13(7), P. e1002191 - e1002191

Published: July 9, 2015

Bacteria form dense surface-associated communities known as biofilms that are central to their persistence and how they affect us. Biofilm formation is commonly viewed a cooperative enterprise, where strains species work together for common goal. Here we explore an alternative model: biofilm response ecological competition. We co-cultured diverse collection of natural isolates the opportunistic pathogen Pseudomonas aeruginosa studied effect on formation. show strain mixing reliably increases compared unmixed conditions. Importantly, leads strong competition: one dominates largely excludes other from biofilm. Furthermore, pyocins, narrow-spectrum antibiotics made by P. strains, can stimulate increasing attachment cells. Side-by-side comparisons using microfluidic assays suggest increase in occurs due general cellular damage: comparable pyocins disrupt membranes commercial damage DNA, inhibit protein synthesis or transcription. Our data bacteria competition detected antibiotic stress. This inconsistent with idea sub-lethal concentrations signals coordinate microbial communities, often concluded. Instead, our consistent sensing low-levels used detect respond competing genotypes produce them.

Language: Английский

Citations

288
Toxicity drives facilitation between 4 bacterial species DOI Creative Commons

Philippe Piccardi,

Björn Vessman,

Sara Mitri

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2019, Volume and Issue: 116(32), P. 15979 - 15984

Published: July 3, 2019

Competition between microbes is extremely common, with many investing in mechanisms to harm other strains and species. Yet positive interactions species have also been documented. What makes help or each currently unclear. Here, we studied the 4 bacterial capable of degrading metal working fluids (MWF), an industrial coolant lubricant, which contains growth substrates as well toxic biocides. We were surprised find only neutral Using mathematical modeling further experiments, show that this community likely due toxicity MWF, whereby species' detoxification benefited others by facilitating their survival, such they could grow degrade MWF better when together. The addition nutrients, reduction toxicity, more instead resulted competitive behavior. Our work provides support stress gradient hypothesis showing how harsh, environments can strongly favor facilitation microbial mask underlying interactions.

Language: Английский

Citations

264