The manifold roles of microbial ribosomal peptide–based natural products in physiology and ecology DOI Creative Commons
Yanyan Li, Sylvie Rebuffat

Journal of Biological Chemistry, Journal Year: 2019, Volume and Issue: 295(1), P. 34 - 54

Published: Nov. 29, 2019

The ribosomally synthesized and posttranslationally modified peptides (RiPPs), also called ribosomal peptide natural products (RPNPs), form a growing superfamily of that are produced by many different organisms particularly bacteria. They derived from precursor polypeptides whose modification various dedicated enzymes helps to establish vast array chemical motifs. RiPPs have attracted much interest as source potential therapeutic agents, in particular alternatives conventional antibiotics address the bacterial resistance crisis. However, their ecological roles nature poorly understood explored. present review describes major RiPP actors competition within microbial communities, main physiological functions currently evidenced for RiPPs, ecosystems sites these functions. We envision study may lead discoveries new biological highlight better knowledge how mediate inter-/intraspecies interkingdom interactions will hold promise devising alternative strategies antibiotic development.

Language: Английский

Spatial structure, cooperation and competition in biofilms DOI
Carey D. Nadell, Knut Drescher, Kevin R. Foster

et al.

Nature Reviews Microbiology, Journal Year: 2016, Volume and Issue: 14(9), P. 589 - 600

Published: July 25, 2016

Language: Английский

Citations

918
The Ecology and Evolution of Microbial Competition DOI
Melanie Ghoul, Sara Mitri

Trends in Microbiology, Journal Year: 2016, Volume and Issue: 24(10), P. 833 - 845

Published: Sept. 19, 2016

Language: Английский

Citations

724
Bacterial Communities: Interactions to Scale DOI Creative Commons
Reed M. Stubbendieck, Carol Vargas-Bautista, Paul D. Straight

et al.

Frontiers in Microbiology, Journal Year: 2016, Volume and Issue: 7

Published: Aug. 8, 2016

In the environment, bacteria live in complex multispecies communities. These communities span scale from small, multicellular aggregates to billions or trillions of cells within gastrointestinal tract animals. The dynamics bacterial are determined by pairwise interactions that occur between different species community. Though a few at time, outcomes these interchanges have ramifications ripple through many orders magnitude, and ultimately affect macroscopic world including health host organisms. this review we cover how competition influences structures We also emphasize methods insights garnered culture-dependent interaction studies, metagenomic analyses, modeling experiments. Finally, argue integration multiple approaches will be instrumental future understanding underlying

Language: Английский

Citations

535
The Evolution and Ecology of Bacterial Warfare DOI Creative Commons
Elisa T. Granato, Thomas A. Meiller-Legrand, Kevin R. Foster

et al.

Current Biology, Journal Year: 2019, Volume and Issue: 29(11), P. R521 - R537

Published: June 1, 2019

Language: Английский

Citations

459
Formation, physiology, ecology, evolution and clinical importance of bacterial persisters DOI Open Access
Bram Van den Bergh, Maarten Fauvart, Jan Michiels

et al.

FEMS Microbiology Reviews, Journal Year: 2017, Volume and Issue: 41(3), P. 219 - 251

Published: Jan. 30, 2017

Persisters are transiently tolerant variants that allow populations to avoid eradication by antibiotic treatment. Their tolerance is non-genetic, not inheritable and results from a phenotypic switch the normal, sensitive cell type tolerant, persister state. Here we give comprehensive overview on bacterial persistence. We first define persistence, summarize various aspects of physiology show their heterogeneous nature. then focus role key cellular processes mechanisms controlling formation subpopulation cells. Being prime example risk-spreading strategy, next discuss eco-evolutionary e.g. how persistence evolves in face treatment with antibiotics. Finally, illustrate clinical importance persisters, as worsening worldwide crisis prolonging treatment, causing therapy failure or catalyzing development genetically encoded resistance. A better understanding this phenotype critical our fight against pathogenic bacteria obtain outlook future therapies.

Language: Английский

Citations

343
The Role of Bacterial Biofilm in Antibiotic Resistance and Food Contamination DOI Creative Commons
Gedif Meseret Abebe

International Journal of Microbiology, Journal Year: 2020, Volume and Issue: 2020, P. 1 - 10

Published: Aug. 25, 2020

Biofilm is a microbial association or community attached to different biotic abiotic surfaces environments. These surface-attached communities can be found in food, medical, industrial, and natural critical problem the medical sector since it formed on implants within human tissue involved multitude of serious chronic infections. Food food processing surface become an ideal environment for biofilm formation where there are sufficient nutrients growth attachment. Therefore, these surfaces, especially becomes challenge safety health. Microorganisms encased matrix extracellular polymeric substances that act as barrier recalcitrant hostile conditions such sanitizers, antibiotics, other hygienic conditions. Generally, they persist exist environments source cross-contamination foodborne diseases. The issue with their antibiotic resistance which makes medication difficult, use physical, physiological, gene-related factors develop mechanisms. In order mitigate production controlling methods, better understand requirements aim this review article provide overview role bacterial biofilms contamination emphasizes ways its production.

Language: Английский

Citations

298
Bacillus velezensis stimulates resident rhizosphere Pseudomonas stutzeri for plant health through metabolic interactions DOI Open Access
Xinli Sun, Zhihui Xu, Jiyu Xie

et al.

The ISME Journal, Journal Year: 2021, Volume and Issue: 16(3), P. 774 - 787

Published: Sept. 30, 2021

Language: Английский

Citations

246
Molecular Aspects of Plant Growth Promotion and Protection byBacillus subtilis DOI Creative Commons
Christopher Blake, Mathilde Nordgaard, Ákos T. Kovács

et al.

Molecular Plant-Microbe Interactions, Journal Year: 2020, Volume and Issue: 34(1), P. 15 - 25

Published: Sept. 28, 2020

Bacillus subtilis is one of the most widely studied plant growth–promoting rhizobacteria. It able to promote growth as well control pathogens through diverse mechanisms, including improvement nutrient availability and alteration phytohormone homeostasis production antimicrobials triggering induced systemic resistance, respectively. Even though its benefits for crop have been recognized extensively under laboratory conditions, success application in fields varies immensely. accepted that agricultural B. often fails because bacteria are not persist rhizosphere. Bacterial colonization roots a crucial step interaction between microbe seems, therefore, be great importance promotion biocontrol effects. A successful root depends thereby on both bacterial traits, motility biofilm formation, signal interplay with plant. This review addresses current knowledge about plant-microbial interactions species, various mechanisms supporting necessity establishment relationship. The author(s) dedicated work public domain Creative Commons CC0 "No Rights Reserved" license by waiving all his or her rights worldwide copyright law, related neighboring rights, extent allowed law.

Language: Английский

Citations

235
Division of Labor during Biofilm Matrix Production DOI Creative Commons
Anna Dragoš, Heiko T. Kiesewalter, Marivic Martin

et al.

Current Biology, Journal Year: 2018, Volume and Issue: 28(12), P. 1903 - 1913.e5

Published: June 1, 2018

Language: Английский

Citations

232
Microbial wars: competition in ecological niches and within the microbiome DOI Creative Commons
Maria A. Bauer, Katharina Kainz, Didac Carmona‐Gutiérrez

et al.

Microbial Cell, Journal Year: 2018, Volume and Issue: 5(5), P. 215 - 219

Published: May 4, 2018

Many microbial communities live in highly competitive surroundings, which the fight for resources determines their survival and genetic persistence. Humans a close relationship with communities, includes health- disease-determining interactions our microbiome. Accordingly, understanding of activities are essential at physiological pathophysiological levels. Here we provide brief overview on competition discuss some its roles consequences that directly affect humans.

Language: Английский

Citations

221