Marine Drugs,
Journal Year:
2025,
Volume and Issue:
23(2), P. 70 - 70
Published: Feb. 7, 2025
In
recent
years,
the
exploration
of
bioactive
molecules
derived
from
natural
sources
has
gained
interest
in
several
application
fields.
Among
these,
macroalgae
have
garnered
significant
attention
due
to
their
functional
properties,
which
make
them
interesting
therapeutic
applications,
including
cancer
treatment.
Cancer
constitutes
a
global
health
burden,
and
side
effects
existing
treatment
modalities
underscore
necessity
for
novel
models
that,
line
with
goal
reducing
drug
treatments,
take
advantage
compounds.
This
review
explores
anticancer
properties
macroalgae,
focusing
on
compounds
mechanisms
action.
The
key
findings
suggest
that
possess
rich
array
compounds,
polysaccharides
(e.g.,
fucoidans
alginates),
polyphenols
phlorotannins),
terpenoids,
exhibit
diverse
activities,
such
as
inhibition
cell
proliferation,
angiogenesis,
induction
apoptosis,
modulation
immune
system.
provides
an
overview
current
understanding
macroalgae’s
potential,
highlighting
most
promising
While
preclinical
studies
shown
results,
further
research
is
necessary
translate
these
into
effective
clinical
applications.
Marine Drugs,
Journal Year:
2024,
Volume and Issue:
22(4), P. 168 - 168
Published: April 10, 2024
Diabetes
mellitus
is
a
chronic
metabolic
condition
marked
by
high
blood
glucose
levels
caused
inadequate
insulin
synthesis
or
poor
use.
This
affects
millions
of
individuals
worldwide
and
linked
to
variety
consequences,
including
cardiovascular
disease,
neuropathy,
nephropathy,
retinopathy.
therapy
now
focuses
on
controlling
through
lifestyle
changes,
oral
medicines,
injections.
However,
these
therapies
have
limits
may
not
successfully
prevent
treat
diabetic
problems.
Several
marine-derived
chemicals
previously
demonstrated
promising
findings
as
possible
antidiabetic
medicines
in
preclinical
investigations.
Peptides,
polyphenols,
polysaccharides
extracted
from
seaweeds,
sponges,
other
marine
species
are
among
them.
As
result,
natural
products
the
potential
be
rich
source
innovative
multitargeted
medications
for
diabetes
prevention
treatment,
well
associated
complications.
Future
research
should
focus
chemical
creatures
mechanisms
action
order
find
new
maximize
their
therapeutic
potential.
Based
investigations,
this
review
next
step
seaweed
applications
diabetes,
highlighting
bioactivities
seaweeds
treatment
illness.
Agronomy,
Journal Year:
2023,
Volume and Issue:
13(8), P. 2092 - 2092
Published: Aug. 9, 2023
The
unsustainable
use
of
natural
resources
and
their
overexploitation
continue
to
be
major
threats
global
agriculture
development.
This
practice
increases
the
abiotic
stresses,
resulting
both
in
crop
yield
losses
soil
degradation.
Low
productivity
is
often
associated
with
salinized
soil,
which
caused
by
toxic
osmotic
effects
soluble
salt
accumulation
and,
consequently,
lack
organic
matter.
Conversely,
there
a
need
improve
current
meet
increasing
food
demands.
Among
methodologies
proposed
increase
plant
resistance
stress,
utilization
production
biostimulants
has
been
recently
proposed.
These
are
products
mainly
based
on
algae,
microorganisms,
fulvic
humic
acids,
proteins,
amino
acids
that
physiological
performance,
leading
increased
productivity.
positive
benefits,
application
can
also
reduce
usage
conventional
chemical
fertilizers.
aim
this
work
was
present
different
saline
conditions.
In
particular,
review,
we
report
critically
discuss
most
recent
research
dealing
growth
salinity
resistance.
Animals,
Journal Year:
2024,
Volume and Issue:
14(4), P. 549 - 549
Published: Feb. 7, 2024
This
study
explores
the
effects
of
dietary
brown
macroalgae
(Ascophyllum
nodosum)
inclusion
on
digestibility
and
blood
biochemical
indices
redox
markers
in
piglets
fed
diets
with
varying
levels
(0%,
0.6%
1%)
from
18
to
64
days
age.
Macroalgae
significantly
influenced
lipid
profiles,
reducing
total
cholesterol
(quadratic
contrast
p
=
0.001)
demonstrating
an
increase
high-density
lipoprotein
levels,
particularly
1%
(linear
<
0.001),
a
decrease
low-density
both
macroalgae-supplemented
groups
0.001).
Additionally,
had
positive
impact
activities
antioxidative
enzymes
(ferric-reducing
ability
plasma,
superoxide
dismutase,
reduced
glutathione)
peroxidation
products
(lipid
hydroperoxide,
malondialdehyde)
blood,
liver
tissue,
intestinal
epithelium
ileum,
suggesting
enhanced
defense
mechanisms.
These
changes
were
dose-dependent;
they
exhibited
linear
quadratic
response,
while
tissues,
response
was
primarily
linear.
crude
fat
observed
highlighting
their
potential
role
improving
nutrient
absorption
digestion.
The
findings
emphasize
health
benefits
natural,
seaweed-based
additives
diets,
managing
oxidative
stress
highlight
as
natural
supplement
improve
antioxidant
systems
metabolism
piglets.
Poultry Science,
Journal Year:
2024,
Volume and Issue:
103(4), P. 103562 - 103562
Published: Feb. 16, 2024
Brown
seaweed
(Ascophyllum
nodosum)
is
known
for
its
prebiotic
roles
and
can
improve
animal
intestinal
health
by
enhancing
the
growth
of
beneficial
microbes
inhibiting
pathogenic
ones.
However,
gut
health-modulatory
brown
on
chickens
challenged
with
heat
stress
(HS)
are
rarely
studied.
The
current
study
examined
effects
meal
(SWM)
extract
(SWE)
ceca
microbiota
small
morphology
or
unchallenged
HS.
Three
hundred
thirty-six
1-day-old
Ross
308
broiler
chicks
were
randomly
assigned
to
either
a
thermoneutral
(TN;
24
±
1°C);
HS
room
(HS;
32-34°C,
8
h/d
from
d
21
27).
All
birds
in
each
allotted
4
treatments
-
control
(CON),
CON
+
1
mL/L
drinking
water,
2
SWE
2%
feed
raised
28
d.
On
14
28,
12
per
treatment
group,
respectively,
euthanized
collect
content
analysis
tissues
morphological
examination.
14,
SWM
increased
(P
=
0.047)
relative
abundance
cecal
Fecalibacterium
all
improved
jejunal
villus
height
(VH)
VH:CD
compared
diet.
significantly
reduced
<
0.05)
ileal
VH,
VW,
VH:CD,
duodenal
VH
VH:CD.
Among
Lactobacillus,
Sellimonas,
Fournierella,
fed
had
higher
other
treatments.
In
summary,
enhanced
among
chickens.
This
implies
that
could
potentially
alleviate
HS-induced
impairment
Poultry Science,
Journal Year:
2022,
Volume and Issue:
101(12), P. 102215 - 102215
Published: Sept. 30, 2022
Brown
seaweed
(Ascophyllum
nodosum)
is
an
exceptional
bioactive
substance
known
for
its
excellent
antioxidant
ability.
Given
the
potential
benefits
of
brown
seaweed,
current
study
was
conducted
to
determine
efficacy
on
growth
performance,
blood
biochemistry,
immunoglobulins
(IgG
and
IgM),
capacity
broiler
chickens
challenged
with
heat
stress
(HS).
A
total
336
mixed-sex
Ross
308
chicks
(one-day-old)
were
randomly
assigned
into
two
groups;
The
thermoneutral
group
(TN,
broilers
raised
at
24
±
1°C);
(HS;
exposed
32°C
34°C,
8
h/d
from
day
21
27;
temperature
in
remaining
time
same
as
TN
group).
All
birds
each
allotted
4
dietary
treatments—Negative
control
(NC)
(without
seaweed),
NC
+
1
mL
extract
(SWE)
drinking
water,
2
SWE
2%
meal
(SWM)
feed.
Each
treatment
six
replicates
7
broilers/replicate.
Average
body
weight
gain
(ABWG),
average
feed
intake
(AFI),
water
(AWI),
conversion
ratio
(FCR),
mortality
determined
weekly.
On
28,
male
birds/cage
euthanized
collect
immune
organs
subsequent
biochemical,
antioxidant,
status
analysis.
Data
analyzed
a
×
factorial
analysis
variance
using
GLM
procedure
Minitab
software.
Overall,
SWM
inclusion
significantly
increased
(P
<
0.05)
AFI,
ABWG,
AWI
irrespective
HS.
HS
reduced
AFI
bird's
rectal
temperature,
plasma
concentrations
sodium,
chloride,
glucose,
amylase,
uric
acid
compared
birds.
serum
IgM
IgG
decreased
glutathione
reductase
peroxidase
birds,
while
activity
superoxide
dismutase
not
affected
by
treatments.
alanine
aminotransferase
gamma-glutamyl
transferase
heat-stressed
broilers,
respectively
other
Conclusively,
supplementation
improved
performance
may
help
reduce
negative
effects
improving
enzyme
activities
Journal of Agriculture and Food Research,
Journal Year:
2024,
Volume and Issue:
17, P. 101239 - 101239
Published: June 5, 2024
Growing
environmental
concerns
and
a
desire
for
health-conscious
food
choices
are
driving
consumer
demand
sustainable
ethical
sources.
Ulva
seaweed
(genus
Ulva,
Phylum
Chlorophyta)
emerges
as
promising
candidate
due
to
its
rich
nutritional
profile,
which
includes
proteins,
carbohydrates,
lipids,
antioxidants.
This
review
explores
the
immense
potential
of
an
eco-friendly
nutritious
source
with
applications
in
industry.
Focusing
on
viability
solution,
we
explore
Ulva's
biochemical
composition,
health
benefits
beyond
established
nutrition,
role
product
development.
While
challenges
remain,
including
variability
nutrient
content,
efficient
harvesting
processing
methods,
ensuring
safety,
minimal
impact
high
value
make
it
compelling
alternative.
Furthermore,
recent
studies
reveal
unique
compounds
possess
impressive
benefits,
antioxidant,
antimicrobial,
antiviral
properties,
offer
exciting
possibilities
human
health.
integration
cultivation
Integrated
Multitrophic
Aquaculture
(IMTA)
systems
demonstrates
feasibility
large-scale
production
while
enhancing
sustainability.
Additionally,
seaweed's
compounds,
properties
like
effects,
offering
provides
valuable
insights
researchers
exploring
seaweed,
readily
available
natural
resource
that
holds
address
global
malnutrition
without
compromising
ecosystem's
Ecotoxicology and Environmental Safety,
Journal Year:
2024,
Volume and Issue:
280, P. 116522 - 116522
Published: June 5, 2024
This
study
aimed
to
evaluate
the
effect
of
adding
liquid
extract
algae
(Hypnea
musciformis,
Grateloupia
acuminata,
and
Sargassum
muticum)
(HGS)
Magnesium
oxide
nanoparticles
(MgO
NPs)
using
this
rear
water
Oreochromis
niloticus,
on
improving
culture
indices,
growth
performance,
digestive
enzyme,
hemato-biochemical
characters,
immune,
antioxidative
responses,
resistance
after
challenged
by
Aeromonas
hydrophila
with
specific
refer
potential
role
mixture
in
vitro
as
against
three
strains
bacteria
(Aeromonas
sobria,
Pseudomonas
fluorescens,
P.
aeruginosa)
one
parasite
(Cichlidogyrus
tilapia).
The
first
group
represented
control,
HGS0,
whereas
other
group,
HGS5,
HGS10,
HGS15
mL
Sustainability,
Journal Year:
2024,
Volume and Issue:
16(17), P. 7436 - 7436
Published: Aug. 28, 2024
This
study
showed
the
eliciting
effect
of
aqueous
extracts
from
Ascophyllum
nodosum
on
development
Eruca
sativa
microgreens
in
a
quartz-based
substrate.
There
is
no
information
literature
impact
its
use
quality,
bioactive
compound
content,
and
nutritional
value
arugula
microgreens.
Assays
that
have
been
made
include
following:
total
phenolic
content
(TPC),
flavonoid
(TFV),
enzymes
such
as
phenylalanine
ammonia
(PAL)
polyphenol
oxidase
(PPO),
involved
scavenging
reactive
oxygen
species
catalase
(CAT)
superoxide
dismutase
(SOD).
The
antioxidant
activity
against
DPPH
(2,2-diphenyl-1-picrylhydrazyl)
was
also
evaluated.
increased
significantly
after
an
application
A.
to
greatest
increase
(89%)
(82%)
observed
at
concentration
2.5%.
highest
CAT
(68.2%),
SOD
(25%),
PAL
(13-fold),
PPO
(84.2%)
with
5%
extract.
In
conclusion,
algae
affects
TPC
TFV,
activity,
PAL,
PPO,
SOD,
studied.
By
prioritising
organic
environmentally
friendly
extracts,
growers
can
contribute
more
sustainable
healthier
food
system,
especially
case
production