The
language
production
deficit
in
post-stroke
agrammatic
aphasia
(PSA-G)
tends
to
result
from
lesions
the
left
inferior
frontal
gyrus
(LIFG)
and
is
characterized
by
a
triad
of
symptoms:
fragmented
sentences,
errors
functional
morphology,
dearth
verbs.
Despite
decades
research,
mechanisms
underlying
patterns
PSA-G
have
been
difficult
characterize.
Two
major
impediments
progress
may
view
that
it
purely
morphosyntactic
disorder
(sometimes
overzealous)
application
linguistic
theory
without
interceding
psycholinguistic
evidence.
In
this
paper,
empirical
evidence
examined
present
an
integrated
portrait
evaluate
assumption
syntax-specific
syndrome.
light
extant
evidence,
proposed
results
combination
morphosyntactic,
phonomotor,
processing
capacity
limitations
cause
cumulative
bottleneck
at
point
articulatory
planning.
This
Synergistic
Processing
Bottleneck
model
presents
testable
framework
for
future
research.
paper
ends
with
recommendations
research
on
PSA-G.
Brain and Language,
Journal Year:
2025,
Volume and Issue:
264, P. 105549 - 105549
Published: Feb. 20, 2025
Although
there
is
a
sizeable
body
of
literature
on
sentence
comprehension
and
processing
both
in
healthy
disordered
language
users,
the
production
remains
much
more
sparse.
Linguistic
computational
descriptions
expressive
syntactic
deficits
aphasia
are
especially
rare.
In
addition,
neuroimaging
(psycho)
linguistic
literatures
operate
largely
separately.
this
paper,
I
will
first
lay
out
theoretical
land
with
regard
to
psycholinguistic
models
production.
then
provide
brief
narrative
overview
large-scale
meta-analysis
as
it
pertains
computation,
followed
by
an
attempt
integrate
findings
from
functional
clinical
neuroimaging.
Finally,
surrounding
propose
path
forward
close
some
existing
gaps.
Abstract
Individuals
with
“agrammatic”
receptive
aphasia
have
long
been
known
to
rely
on
semantic
plausibility
rather
than
syntactic
cues
when
interpreting
sentences.
In
contrast
early
interpretations
of
this
pattern
as
indicative
a
deficit
in
knowledge,
recent
proposal
views
agrammatic
comprehension
case
“noisy-channel”
language
processing
an
increased
expectation
noise
the
input
relative
healthy
adults.
Here,
we
investigate
nature
model
and
whether
it
is
adapted
statistics
environment.
We
first
replicate
findings
that
a)
adults
(
N
=
40)
make
inferences
about
intended
meaning
sentence
by
weighing
prior
probability
against
likelihood
corruption
b)
their
estimate
increases
there
are
more
errors
(manipulated
via
exposure
sentences).
then
extend
chronic
post-stroke
28)
age-matched
19)
similarly
engage
noisy-channel
inference
during
comprehension.
use
hierarchical
latent
mixture
modeling
approach
account
for
fact
rates
guessing
likely
differ
between
controls
individuals
capture
individual
differences
tendency
inferences.
show
draw
semantically
implausible
sentences,
even
group
guess
accounted
for.
While
rapidly
adapt
increase
input,
do
same
remains
equivocal.
Further
investigation
through
lens
holds
promise
parsimonious
understanding
may
suggest
potential
avenues
treatment.
Journal of Speech Language and Hearing Research,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 18
Published: March 31, 2025
Purpose:
Although
there
is
widespread
agreement
pertaining
to
the
cognitive
processes
underlying
spoken
word
production,
more
generally
in
aphasia,
multiple
competing
accounts
exist
regarding
involved
for
verb
specifically.
Some
have
speculated
that
suboptimal
control
of
certain
item
properties
(e.g.,
imageability)
may
be
partially
responsible
conflicting
reports
literature,
yet
remains
a
dearth
research
on
psychometric
validation
production
tests
aphasia.
The
purpose
present
study
was
investigate
constructs
Verb
Naming
Test
(VNT),
relatively
commonly
used
test,
by
expanding
upon
an
response
theory
(IRT)
modeling
framework
we
previously
described.
Method:
Using
archival
data
set
107
individuals
with
specified
series
IRT
models
whether
covariates
(argument
structure,
imageability),
person
(aphasia
subtype,
severity),
and
their
interactions
were
predictive
VNT
patterns.
Results:
Across
all
models,
most
strongly
associated
lexical-semantic
processing
(imageability,
aphasia
severity)
significant
predictors.
In
contrast,
morphosyntactic
subtype)
minimally
predictive.
Conclusions:
patterns
appear
primarily
explained
representing
processing.
particular,
identified
important
role
imageability,
covariate
not
controlled
VNT's
design,
which
both
aligns
body
prior
further
illustrates
challenge
differentiating
from
lexical
semantic
during
production.
Supplemental
Material:
https://doi.org/10.23641/asha.28664669
Cognitive Neuropsychology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 25
Published: April 3, 2025
This
study
applies
implicit
structural
priming
as
a
novel
treatment
for
sentence
production
in
persons
with
aphasia
(PWA),
investigating
the
learning
mechanism(s)
that
drive
robust
and
enduring
recovery.
Sixteen
PWA
16
controls
completed
baseline,
three
training
sessions,
1-day
1-week
post-testing.
Each
participant
received
both
alternating
single
structure
prime
conditions
to
test
error-based
versus
repeated
activation-based
learning.
Both
groups
showed
significantly
improved
maintenance
of
trained
untrained
target
sentences
conditions.
While
greater
gains
following
training,
resulted
improvements
PWA.
These
results
suggest
is
an
effective
aphasia.
Additionally,
extent
different
reflected
mechanisms
underlying
access
impaired
structure,
increased
base-level
activation
syntactic
supports
grammatical
encoding
more
effectively
than
processing
competing
structures.
Aphasiology,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 33
Published: June 19, 2024
Background
Agrammatism
in
agglutinative
languages
exhibits
preservation
of
verb
morphology
due
to
their
rich
morphological
paradigms.
Tagalog,
an
language
mainly
spoken
the
Philippines,
remains
uncharacterized
agrammatism
yet
holds
potential
for
future
research
that
can
challenge
existing
theories
and
help
advance
novel
ones.
Frontiers in Language Sciences,
Journal Year:
2023,
Volume and Issue:
2
Published: Sept. 15, 2023
The
language
production
deficit
in
post-stroke
agrammatic
aphasia
(PSA-G)
tends
to
result
from
lesions
the
left
inferior
frontal
gyrus
(LIFG)
and
is
characterized
by
a
triad
of
symptoms:
fragmented
sentences,
errors
functional
morphology,
dearth
verbs.
Despite
decades
research,
mechanisms
underlying
patterns
PSA-G
have
been
difficult
characterize.
Two
major
impediments
progress
may
view
that
it
purely
morphosyntactic
disorder
(sometimes
overzealous)
application
linguistic
theory
without
interceding
psycholinguistic
evidence.
In
this
paper,
empirical
evidence
examined
present
an
integrated
portrait
evaluate
assumption
syntax-specific
syndrome.
light
extant
evidence,
proposed
results
combination
morphosyntactic,
phonomotor,
processing
capacity
limitations
cause
cumulative
bottleneck
at
point
articulatory
planning.
This
Synergistic
Processing
Bottleneck
model
presents
testable
framework
for
future
research.
paper
ends
with
recommendations
research
on
PSA-G.
Brain,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 18, 2024
Abstract
There
is
a
rich
tradition
of
research
on
the
neuroanatomical
correlates
spoken
language
production
in
aphasia
using
constrained
tasks
(e.g.,
picture
naming),
which
offer
controlled
insights
into
distinct
processes
that
govern
speech
and
(i.e.,
lexical-semantic
access,
morphosyntactic
construction,
phonological
encoding,
motor
programming/execution).
Yet
these
do
not
necessarily
reflect
everyday
use.
In
contrast,
naturalistic
(also
referred
to
as
connected
or
discourse)
more
closely
approximates
typical
processing
demands,
requiring
dynamic
integration
all
aspects
language.
The
brain
bases
remain
relatively
unknown,
however,
part
because
difficulty
deriving
features
are
salient,
quantifiable,
interpretable
relative
both
speech-language
extant
literature.
present
cross-sectional
observational
study
seeks
address
challenges
by
leveraging
validated
comprehensive
auditory-perceptual
measurement
system
yields
four
explanatory
dimensions
performance—Paraphasia
(misselection
words
sounds),
Logopenia
(paucity
words),
Agrammatism
(grammatical
omissions),
Motor
(impaired
We
used
this
characterize
large
representative
sample
individuals
with
acute
post-stroke
(n
=
118).
Scores
each
were
correlated
lesion
metrics,
multivariate
associations
among
regions
then
explored.
Our
findings
revealed
yet
overlapping
throughout
left-hemisphere
network.
Paraphasia
associated
primarily
posterior
regions,
spanning
dorsal
ventral
streams,
critical
for
access
encoding.
anterior
stream
involved
construction
planning/execution
respectively.
Collectively,
we
view
results
constituting
brain-behavior
model
aphasia,
aligning
historical
contemporary
accounts
neurobiology
production.
