The Promise of Neurolaw in Global Justice: An Interview with Dr. Pragya Mishra
Alan Logan,
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Pragya Mishra
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Challenges,
Journal Year:
2025,
Volume and Issue:
16(1), P. 15 - 15
Published: March 6, 2025
In
an
ongoing
series
of
interviews,
Challenges
Advisory
Board
member
and
Nova
Institute
for
Health
Fellow
Alan
C.
Logan
meets
with
thought
leaders,
scientists,
scholars,
healthcare
professionals,
artisans,
visionaries
concerned
about
health
at
the
scale
individuals,
communities,
planet.
Here,
Dr.
Pragya
Mishra
responds
to
a
set
questions
posed
by
Challenges.
Mishra,
legal
academician
one
few
global
scholars
PhD
specifically
in
neurolaw,
is
forefront
research
examining
intersection
law
brain
sciences.
As
concept
developing
field,
promise
neurolaw
that
it
will
lead
more
equitable
less
punitive
justice
system,
based
on
objective
science
rather
than
prescientific
assumptions
blameworthiness
willpower.
reflects
promises
pitfalls
growing
challenges
free
held
courts,
her
work
field
epitomizes
transdisciplinary
effort.
She
discusses
place
contemplative
practices
within
special
emphasis
hope
rehabilitation.
describes
through
holistic
lens,
embraces
future
possibilities
shaping
evidence-based
policy
changes.
While
planetary
as
broad
term,
has
paid
little
attention
criminal
system.
Discussions
are
important
ethical
frameworks
health.
Neurolaw,
explains,
heart
many
interconnected
our
time.
Language: Английский
Abnormal microbiota due to prenatal antibiotic as a possible risk factor for Attention-Deficit / Hyperactivity Disorder (ADHD)
International review of neurobiology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 299 - 328
Published: Jan. 1, 2025
Language: Английский
The Trials and Errors of Developing an Experimental Model to Study the Impact of Maternal Gut Microbiome Disruption on Perinatal Asphyxia
Mara Ioana Ionescu,
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Ana-Maria Catrina,
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IULIANA DOGARU
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et al.
Reproduction and Fertility,
Journal Year:
2024,
Volume and Issue:
5(4)
Published: Oct. 1, 2024
Abstract
Maternal
gut
microbiome
impairment
has
garnered
attention
for
its
potential
role
in
influencing
neurodevelopmental
outcomes
offspring,
especially
situations
that
increase
brain
vulnerability
such
as
perinatal
asphyxia
(PA).
and
fetal
interplay
emerge
a
critical
link
between
maternal
health
offspring
neurodevelopment.
This
study
aims
to
generate
model
assess
the
impact
of
dysbiosis
triggered
by
gestational
antibiotic
administration
PA
on
Wistar
rats
were
subjected
antibiotics
drinking
water
from
11th
day
until
birth.
On
6th
postnatal
day,
pups
PA/normoxia,
resulting
four
experimental
groups:
control-normoxia,
antibiotics-normoxia,
control-asphyxia,
antibiotics-asphyxia.
Early-life
behavioral
tests
conducted
days
7
9.
The
initial
antimicrobial
cocktail
(ampicillin,
vancomycin,
neomycin,
clindamycin,
amphotericin-B)
led
an
increased
number
miscarriages,
poor
weight
gain
during
pregnancy,
reduced
weight,
changes
compared
control.
Offspring
presented
impaired
reflexes
both
groups
hippocampal
neuroinflammation.
Due
these
detrimental
effects,
more
pregnancy-safe
was
used
second
experiment
meropenem).
resulted
no
miscarriages
or
pregnancy-weight
loss
but
still
linked
disruption.
neuroinflammation,
effects
amplified
administration.
These
preliminary
findings
reveal
cumulative
neurodevelopment
impairment,
emphasizing
caution
use.
Further
investigations
should
include
long-term
follow-up
behavior
integrate
probiotics
counteract
effects.
Graphical
abstract
Lay
summary
investigates
disruptions
caused
treatment
low
oxygen
exposure
shortly
after
birth
development
rats’
babies.
We
found
levels
early
inflammation
nervous
tissue
baby
rats.
Although
using
different,
potentially
safer
combination
pregnancy
complications,
it
changed
bacteria
mother’s
worsened
behavior.
show
can
affect
developing
careful
consideration
be
before
prescribing
them.
Future
research
will
explore
longer-term
medicines.
Language: Английский