A critical review on the sustainable synthesis of pyrimidine-based heterocycles and their biological activities
Viphrezolie Sorhie,
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Tsenbeni N. Lotha,
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Susital Mal
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et al.
Tetrahedron,
Journal Year:
2025,
Volume and Issue:
unknown, P. 134626 - 134626
Published: March 1, 2025
Language: Английский
Synthesis of coumarin-linked naphthoquinone fused pyrrole derivatives by HFIP-mediated multicomponent reaction
Ujjain Chaurasia,
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Tasneem Parvin
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Journal of Chemical Sciences,
Journal Year:
2023,
Volume and Issue:
135(3)
Published: June 23, 2023
Language: Английский
Efficient, Concise, and Chemoselective Synthesis of 1H‐Benzo[f]indole‐4,9‐dione with 4‐Hydroxycoumarin Substituent via a One‐Pot Three‐Component Reaction
ChemistrySelect,
Journal Year:
2023,
Volume and Issue:
8(48)
Published: Dec. 19, 2023
Abstract
Extensive
studies
on
the
biological
activities
of
several
quinone‐fused
heterocycles
have
confirmed
their
outstanding
antitumor
activity.
Therefore,
a
new
family
1
H
‐benzo[
f
]indole‐4,9‐dione
derivatives
with
4‐hydroxycoumarin
substitution
was
prepared
by
high‐yield,
one‐pot,
concise
three‐component
reaction
between
arylglyoxals,
4‐hydroxycoumarin,
and
2‐aminonaphthalene‐1,4‐dione
under
reflux
in
EtOH.
This
efficient
protocol
showed
chemoselectivity
addition
to
facile
operation
procedure
easy
purification.
Language: Английский