Genetic-bioengineering of nanotechnology in cell-specific pharmaceutical targeting: Biological, pharmacological, and biochemical impact of nanomaterials-based breast cancer therapies DOI
Javad Mohammadi, Sina Ebrahimi,

Maryam Ghodousi

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: unknown, P. 106249 - 106249

Published: Oct. 1, 2024

Language: Английский

Advancing neurological disorders therapies: Organic nanoparticles as a key to blood-brain barrier penetration DOI Creative Commons
Zahra Razavi,

Seyed Sina Alizadeh,

F. S. Razavi

et al.

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: 670, P. 125186 - 125186

Published: Jan. 8, 2025

The blood-brain barrier (BBB) plays a vital role in protecting the central nervous system (CNS) by preventing entry of harmful pathogens from bloodstream. However, this also presents significant obstacle when it comes to delivering drugs for treatment neurodegenerative diseases and brain cancer. Recent breakthroughs nanotechnology have paved way creation wide range nanoparticles (NPs) that can serve as carriers diagnosis therapy. Regarding their promising properties, organic NPs potential be used effective drug delivery across BBB based on recent advancements. These remarkable ability penetrate using various mechanisms. This review offers comprehensive examination intricate structure distinct properties BBB, emphasizing its crucial function preserving balance regulating transport ions molecules. disruption conditions such stroke, Alzheimer's disease, Parkinson's disease highlights importance developing creative approaches drugs. Through encapsulation therapeutic molecules precise targeting processes vasculature, NP formulations present hopeful strategy improve BBB. We explore changes pathological investigate factors affect successful into brain. In addition, we most systems associated with shown positive results treating ischemic disorders. opens up new possibilities nanotechnology-based therapies cerebral diseases.

Language: Английский

Citations

8

Application of novel strategies in chronic wound management with focusing on pressure ulcers: new perspective DOI

Zahra Sadat Razavi,

Shahrzad Aliniay Sharafshadehi,

Mohammad Hasan Yousefi

et al.

Archives of Dermatological Research, Journal Year: 2025, Volume and Issue: 317(1)

Published: Jan. 31, 2025

Language: Английский

Citations

5

Inorganic Nanoparticles and Blood-Brain Barrier Modulation: Advancing Targeted Neurological Therapies DOI
Zahra Razavi, F. S. Razavi,

Seyed Sina Alizadeh

et al.

European Journal of Medicinal Chemistry, Journal Year: 2025, Volume and Issue: 287, P. 117357 - 117357

Published: Feb. 5, 2025

Language: Английский

Citations

5

Genomic synergy in food traceability: Enhancing global food safety and security DOI
Jacob Tizhe Liberty

Ecological Genetics and Genomics, Journal Year: 2025, Volume and Issue: 34, P. 100324 - 100324

Published: Jan. 5, 2025

Language: Английский

Citations

1

CRISPR integrated biosensors: A new paradigm for cancer detection DOI

Ashok Saini,

Neeraj Dilbaghi, Neelam Yadav

et al.

Clinica Chimica Acta, Journal Year: 2025, Volume and Issue: 569, P. 120179 - 120179

Published: Feb. 1, 2025

Language: Английский

Citations

1

Advances and applications of hyperthermia in tumor therapy: Mechanisms, techniques, and clinical integration DOI

Cui-Hua Gu,

Jinzhong Zhang, Jinsong Zeng

et al.

International Communications in Heat and Mass Transfer, Journal Year: 2025, Volume and Issue: 164, P. 108895 - 108895

Published: March 29, 2025

Language: Английский

Citations

1

CRISPR innovations in tissue engineering and gene editing DOI Creative Commons

ZahraSadat Razavi,

M. Soltani, Mohammad Souri

et al.

Life Sciences, Journal Year: 2024, Volume and Issue: unknown, P. 123120 - 123120

Published: Oct. 1, 2024

Language: Английский

Citations

8

Current Biosensing Strategies Based on In Vitro T7 RNA Polymerase Reaction DOI Open Access
David Septian Sumanto Marpaung, Ayu Oshin Yap Sinaga, Damayanti Damayanti

et al.

Biotechnology Notes, Journal Year: 2025, Volume and Issue: 6, P. 59 - 66

Published: Jan. 1, 2025

Recently, a unique behavior of T7 RNA polymerase has expanded its functionality as biosensing platform. Various biosensors utilizing polymerase, combined with fluorescent aptamers, electrochemical probes, or CRISPR/Cas systems, have been developed to detect analytes, including nucleic acids and non-nucleic acid target, high specificity low detection limits. Each approach demonstrates strengths, such real-time monitoring minimal interference, but also presents challenges in stability, cost, reaction optimization. This review provides an overview polymerase's role technology, highlighting potential advance diagnostics molecular diverse fields.

Language: Английский

Citations

0

Mesenchymal stromal cells in bone marrow niche of patients with multiple myeloma: a double-edged sword DOI Creative Commons

Sina Kamrani,

Reza Naseramini,

Pouria Khani

et al.

Cancer Cell International, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 26, 2025

Abstract Multiple myeloma (MM) is a hematological malignancy defined by the abnormal proliferation and accumulation of plasma cells (PC) within bone marrow (BM). While multiple impacts bone, it not classified as primary cancer. The microenvironment significantly influences progression its treatment response. Mesenchymal stromal (MSCs) in this environment engage with other components via direct contact secretion soluble factors. This review examines established roles MSCs facets MM pathology, encompassing their pro-inflammatory functions, contributions to tumor epigenetics, effects on immune checkpoint inhibitors (ICIs), influence reprogramming, chemotherapy resistance, senescence. investigates role development MM.

Language: Английский

Citations

0

Mesenchymal stem cells and their exosomes: a novel approach to skin regeneration via signaling pathways activation DOI

Maryam Kananivand,

Fatemeh Nouri,

Mohammad Hasan Yousefi

et al.

Journal of Molecular Histology, Journal Year: 2025, Volume and Issue: 56(2)

Published: April 1, 2025

Language: Английский

Citations

0