Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 307 - 327
Published: Jan. 1, 2024
Language: Английский
Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 307 - 327
Published: Jan. 1, 2024
Language: Английский
Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: unknown, P. 106543 - 106543
Published: Dec. 1, 2024
Language: Английский
Citations
1Journal of Drug Delivery Science and Technology, Journal Year: 2022, Volume and Issue: 75, P. 103709 - 103709
Published: Aug. 22, 2022
Language: Английский
Citations
5Life, Journal Year: 2023, Volume and Issue: 13(10), P. 1976 - 1976
Published: Sept. 27, 2023
Prostate cancer (CaP) is one of the most prevalent male malignancies, accounting for a considerable number annual mortalities. However, prompt identification early-stage CaP often faces delays due to diverse factors, including socioeconomic inequalities. The androgen receptor (AR), in conjunction with various other signaling pathways, exerts central influence on genesis, progression, and metastasis CaP, deprivation therapy (ADT) serving as primary therapeutic strategy. Therapeutic modalities encompassing surgery, chemotherapy, hormonal intervention, radiotherapy have been formulated addressing early metastatic CaP. Nonetheless, heterogeneous tumor microenvironment frequently triggers activation culminating emergence chemoresistance, an aspect which stem cells (CSCs) notably contribute. Phytochemicals emerge reservoirs bioactive agents conferring manifold advantages against human morbidity. Several these phytochemicals demonstrate potential chemoprotective chemosensitizing properties selectivity exhibited towards malignant while sparing their normal counterparts. In this context, present review aims elucidate intricate molecular underpinnings associated development acquisition chemoresistance. Moreover, contributions ameliorating initiation, chemoresistance are also discussed.
Language: Английский
Citations
2Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 33 - 45
Published: Jan. 1, 2024
Language: Английский
Citations
0Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 307 - 327
Published: Jan. 1, 2024
Language: Английский
Citations
0