Oral Oncology Reports, Journal Year: 2024, Volume and Issue: 11, P. 100642 - 100642
Published: Sept. 1, 2024
Language: Английский
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(11), P. 5842 - 5842
Published: May 27, 2024
This study provides a brief discussion of the major nanopharmaceuticals formulations as well impact nanotechnology on future pharmaceuticals. Effective and eco-friendly strategies biofabrication are also highlighted. Modern approaches to designing pharmaceutical nanoformulations (e.g., 3D printing, Phyto-Nanotechnology, Biomimetics/Bioinspiration, etc.) outlined. paper discusses need use natural resources for “green” design new with therapeutic efficiency. Nanopharmaceuticals research is still in its early stages, preparation nanomaterials must be carefully considered. Therefore, safety long-term effects not overlooked. The testing represents an essential point their further applications. Vegetal scaffolds obtained by decellularizing plant leaves represent valuable, bioinspired model nanopharmaceutical that avoids using animals. Nanoformulations critical various fields, especially pharmacy, medicine, agriculture, material science, due unique properties advantages over conventional allows improved solubility, bioavailability, targeted drug delivery, controlled release, reduced toxicity. have transitioned from experimental stages being vital component clinical practice, significantly improving outcomes medical fields cancer treatment, infectious diseases, neurological disorders, personalized advanced diagnostics. Here key points highlighting importance. significant challenges, opportunities, directions mentioned final section.
Language: Английский
Citations
22
Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(7), P. 932 - 932
Published: July 12, 2024
Cancer remains a significant global health challenge, with traditional therapies like surgery, chemotherapy, and radiation often accompanied by systemic toxicity damage to healthy tissues. Despite progress in treatment, these approaches have limitations such as non-specific targeting, toxicity, resistance development cancer cells. In recent years, nanotechnology has emerged revolutionary frontier therapy, offering potential solutions challenges. Nanoparticles, due their unique physical chemical properties, can carry therapeutic payloads, navigate biological barriers, selectively target Metal-based nanoparticles, particular, offer properties suitable for various applications. Recent advancements focused on the integration of metal-based nanoparticles enhance efficacy precision photodynamic therapy. Integrating into therapy represents paradigm shift, enabling strategies enhanced specificity reduced off-target effects. This review aims provide comprehensive understanding pivotal role We explore mechanisms, biocompatibility, applications highlighting challenges use, well combining nanoparticles/photodynamic other synergistic approach treatment.
Language: Английский
Citations
7
Frontiers in Oncology, Journal Year: 2025, Volume and Issue: 14
Published: Jan. 8, 2025
Photodynamic diagnosis (PDD) and autofluorescence imaging (AFI) are emerging cancer diagnostic technologies that offer significant advantages over traditional white-light endoscopy in detecting precancerous lesions early-stage cancers; moreover, they hold promising potential fluorescence-guided surgery (FGS) for tumors. However, their shortcomings have somewhat hindered the clinical application of PDD AFI. Therefore, it is imperative to enhance efficacy AFI, thereby maximizing practical use. This article reviews principles, characteristics, current research status, advancements focusing on analyzing discussing optimization strategies AFI tumor FGS scenarios. Considering technical feasibility, optimizing may result an effective real-time tool guide clinicians surgical guidance achieve best results.
Language: Английский
Citations
0
Materials Letters, Journal Year: 2025, Volume and Issue: 388, P. 138300 - 138300
Published: Feb. 26, 2025
Language: Английский
Citations
0
Oral Oncology Reports, Journal Year: 2024, Volume and Issue: 11, P. 100642 - 100642
Published: Sept. 1, 2024
Language: Английский
Citations
3