Invasive group A streptococcal infections in Europe after the COVID-19 pandemic

Deutsches Ärzteblatt international, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 26, 2024

The incidence of airborne respiratory infections fell as a result the protective measures taken during COVID-19 pandemic and rose again when these were stopped. In 2022, there was notable rise in invasive group A streptococcal (iGAS) many countries, including Germany. This also reflected data university otorhinolaryngology department Ulm,

Language: Английский

---

Using a Bayesian hierarchical approach to study the association between non-pharmaceutical interventions and the spread of Covid-19 in Germany

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Nov. 2, 2023

Non-Pharmaceutical Interventions (NPIs) are community mitigation strategies, aimed at reducing the spread of illnesses like coronavirus pandemic, without relying on pharmaceutical drug treatments. This study aims to evaluate effectiveness different NPIs across sixteen states Germany, for a time period 21 months pandemic. We used Bayesian hierarchical approach that combines sub-models and merges information from complementary sources, estimate true unknown number infections. In this framework, we data reported cases, hospitalizations, intensive care unit occupancy, deaths effect NPIs. The list includes: "contact restriction (up 5 people)", "strict contact restriction", "curfew", "events permitted up 100 people", "mask requirement in shopping malls", "restaurant closure", "restaurants only with test", "school closure" "general behavioral changes". found considerable reduction instantaneous reproduction by changes", "curfew". No association school closures could be found. suggests some public health measures, including general changes, strict restrictions, restaurants tests associated containing Covid-19 Future research is needed better understand context vaccination.

Language: Английский

---

A longitudinal cohort study on the use of health and care services by older adults living at home with/without dementia before and during the COVID-19 pandemic: the HUNT study

BMC Health Services Research, Journal Year: 2024, Volume and Issue: 24(1)

Published: April 19, 2024

Abstract Background Older adults and people with dementia were anticipated to be particularly unable use health care services during the lockdown period following COVID-19 pandemic. To better prepare for future pandemics, we aimed investigate whether of changed pandemic those at older ages and/or experienced a higher degree change than that observed by their counterparts. Methods Data from Norwegian Trøndelag Health Study (HUNT4 70 + , 2017–2019) linked two national registries have individual-level data on primary specialist services. A multilevel mixed-effects linear regression model was used calculate changes in 18 months before lockdown, (12 March 2020) after lockdown. Results The study sample included 10,607 participants, 54% women 11% had dementia. mean age 76 years (SD: 5.7, range: 68–102 years). decrease service use, except contact general practitioners (GPs), ( p < 0.001) aged ≥ 80 without = 0.006), compared 6-month decreased all groups ≤ 0.011), Service reached levels comparable pre-pandemic within one year Conclusion an immediate reduction services, other GP contacts, first wave Within demonstrated more pronounced dementia; otherwise, variations related status small. Both returned similar increase contacts may indicate need reallocate resources pandemics. Trial registration is registered ClinicalTrials.gov, identification number NCT 04792086.

Language: Английский

---

Rise in complications of acute otitis media during and after the COVID-19 pandemic

European Archives of Oto-Rhino-Laryngology, Journal Year: 2024, Volume and Issue: 281(9), P. 4627 - 4633

Published: May 6, 2024

Abstract Purpose After the lifting of nonpharmaceutical interventions (NPIs) during COVID-19 pandemic, clinical observation showed an increase in complications acute otitis, followed by a rise number mastoidectomies performed. The aim this study was to record performed before, and after pandemic as indicator for otitis media. Methods Data were collected from tertiary hospital university setting, well four major public health insurance companies Germany. data 24,824,763 German citizens period 2014 until 2023 analyzed. Results According data, dropped 54% children aged 0–6 62% 7–18. For adults, there 30% fewer between 2020 2022. most NPI’s season July 2022 June 2023, sharp on patients all ages. Conclusions During decrease seen, suggesting lower incidence complicated likely linked general upper airway infections due NPI’s. In contrast, occurred hygiene measures lifted. current development causes more frequent performance mastoidectomies, thus entailing change challenges everyday practice.

Language: Английский

---

Epidemiology of common infectious diseases before and during the COVID-19 pandemic in Bavaria, Germany, 2016 to 2021: an analysis of routine surveillance data

Eurosurveillance, Journal Year: 2023, Volume and Issue: 28(41)

Published: Oct. 12, 2023

BackgroundUnprecedented non-pharmaceutical interventions to control the COVID-19 pandemic also had an effect on other infectious diseases.AimWe aimed determine their impact transmission and diagnosis of notifiable diseases than in Bavaria, Germany, 2020 2021.MethodsWe compared weekly cases 15 recorded Bavaria between 1 January 2016 31 December 2021 time series analyses, median age time-to-diagnosis using Wilcoxon rank sum test hospitalisation rates univariable logistic regression during three periods: pre-pandemic (weeks 2016-9 2020), years 10-52 2020) 2 (2021).ResultsWeekly case numbers decreased year for all assessed except influenza, Lyme disease tick-borne encephalitis; markedly norovirus gastroenteritis (IRR = 0.15; 95% CI: 0.12-0.20) pertussis 0.22; 0.18-0.26). In 2, influenza 0.04; 0.02-0.09) 0.11; 0.09-0.14) markedly, but chickenpox, dengue fever,

Language: Английский

---

Impact of the COVID‐19 pandemic on the circulation of other pathogens in England

Journal of Medical Virology, Journal Year: 2022, Volume and Issue: 95(1)

Published: Dec. 13, 2022

Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by authors. Any queries (other than missing content) should be directed to corresponding author article.

Language: Английский

---

Comparison of 14 respiratory pathogens among hospitalized children during and after the COVID-19 outbreak in Chaoshan area

Virology Journal, Journal Year: 2023, Volume and Issue: 20(1)

Published: April 18, 2023

Abstract Background Since January 2020, measures has been adopted in the Chaoshan area to limit spread of COVID-19. Restrictions were removed after August 2020. At same time, children returned school. We previously reported changes 14 main respiratory pathogens hospitalized before and during COVID-19 outbreak area. However, pathogen spectrum epidemic are still unknown, which will be elucidated this study. Methods There 6201 with tract infection enrolled study, divided into two groups: 2533 from group (1 2020–31 December 2020), 3668 post-outbreak 2021–31 2021). Pharyngeal swab samples collected. detected by liquid chip technology. Results The positive rate detection is significantly lower (65.42%, 1657/2533) than that (70.39%, 2582/3668; χ 2 = 17.15, P < 0.05). Influenza A virus (FluA) was 1.9% (49) but 0% (0) 2021. rates Bordetella pertussis (BP) decreased 1.4% (35) 2020 0.5% (17) In contrast, B (FluB), Cytomegalovirus (CMV), Haemophilus influenzae (HI), Streptococcus pneumoniae (SP) increased 0.3% (8), 24.7% (626), 2.0% (50) 19.4% (491) 3.3% (121), 27.9% (1025), 4.6% (169), 22.8% (836) 2021, respectively ( 0.01). Conclusions such as FluA, FluB, CMV, HI, SP, BP statistically different between From Flu, HI SP increased, while FluA decreased. After prevention control gradually relaxed, aged 6 months years increase.

Language: Английский

---

The burden of seasonal influenza: improving vaccination coverage to mitigate morbidity and its impact on healthcare systems

Expert Review of Vaccines, Journal Year: 2023, Volume and Issue: 22(1), P. 518 - 519

Published: June 2, 2023

Language: Английский

---

Orbital complications of sinusitis in children - Retrospective analysis of an 8.5 year experience

International Journal of Pediatric Otorhinolaryngology, Journal Year: 2024, Volume and Issue: 177, P. 111865 - 111865

Published: Jan. 19, 2024

Orbital complications account for approximately 74–85 % of all acute sinusitis, affect the pediatric population more frequently, and can have devastating consequences. In years following COVID-19 pandemic (2022, 2023), a high number children presented to our clinic with orbital complications. 1)Has there been an increase in post-covid era? 2)To what extent has use MRI reduced radiation patients? retrospective data analysis, patients (age 0–16 years) treated at university ENT during period 01/2014-06/2023 who complication rhinosinusitis were included. The analysis was descriptive. Forty-four study period, 14 females 30 males. Most (n = 23, 52 %) waning Covid-19 (01/2022 06/2023). initial imaging modality 22,50 %); CT performed 17 44 cases (39 when surgery indicated. most common germ detected Streptococcus species, predominant antibiotic administered amipicillin/sulbactam. standard operating procedure (SOP) established hospital 2014 followed 42/44 cases. Except 2 cases, exclusively Imaging-related could be avoided 27 (61 %). There related sinus infections postpandemically.

Language: Английский

---

SIR+ models: accounting for interaction-dependent disease susceptibility in the planning of public health interventions

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: June 5, 2024

Avoiding physical contact is regarded as one of the safest and most advisable strategies to follow reduce pathogen spread. The flip side this approach that a lack social interactions may negatively affect other dimensions health, like induction immunosuppressive anxiety depression or preventing importance with diversity microbes, which be necessary train our immune system maintain its normal levels activity. These in turn population's susceptibility infection incidence severe disease. We suggest future pandemic modelling benefit from relying on 'SIR+ models': epidemiological models extended account for benefits resilience. develop an SIR+ model discuss specific interventions more effective balancing trade-off between minimizing spread maximizing interaction-dependent health benefits. Our reflects idea not just mere absence disease, but rather state physical, mental well-being can also dependent same connections allow spread, public pandemics should multidimensionality.

Language: Английский

---