New Perspectives of Hydrogels in Chronic Wound Management
Molecules,
Journal Year:
2025,
Volume and Issue:
30(3), P. 686 - 686
Published: Feb. 4, 2025
Chronic
wounds
pose
a
substantial
healthcare
concern
due
to
their
prevalence
and
cost
burden.
This
paper
presents
detailed
overview
of
chronic
emphasizes
the
critical
need
for
novel
therapeutic
solutions.
The
pathophysiology
wound
healing
is
discussed,
including
stages
factors
contributing
chronicity.
focus
on
diverse
types
wounds,
such
as
diabetic
foot
necrosis,
pressure
ulcers,
venous
leg
highlighting
etiology,
consequences,
issues
they
provide.
Further,
modern
care
solutions,
particularly
hydrogels,
are
highlighted
tackling
challenges
management.
Hydrogels
characterized
multipurpose
materials
that
possess
vital
characteristics
like
capacity
retain
moisture,
biocompatibility,
incorporation
active
drugs.
Hydrogels’
effectiveness
in
applications
demonstrated
by
how
support
healing,
preserving
ideal
moisture
levels,
promoting
cellular
migration,
possessing
antibacterial
properties.
Thus,
this
hydrogel
technology’s
latest
developments,
emphasizing
drug-loaded
stimuli-responsive
underscoring
these
advanced
formulations
greatly
improve
therapy
outcomes
enabling
dynamic
focused
reactions
environment.
Future
directions
research
promote
development
customized
treatments
digital
health
tools
treatment
wounds.
Language: Английский
3D Printing‐Based Hydrogel Dressings for Wound Healing
Xuan Zhou,
No information about this author
Xunzhou Yu,
No information about this author
Tingting You
No information about this author
et al.
Advanced Science,
Journal Year:
2024,
Volume and Issue:
11(47)
Published: Nov. 18, 2024
Abstract
Skin
wounds
have
become
an
important
issue
that
affects
human
health
and
burdens
global
medical
care.
Hydrogel
materials
similar
to
the
natural
extracellular
matrix
(ECM)
are
one
of
best
candidates
for
ideal
wound
dressings
most
feasible
choices
printing
inks.
Distinct
from
hydrogels
made
by
traditional
technologies,
which
lack
bionic
mechanical
properties,
3D
can
promptly
accurately
create
with
complex
bioactive
structures
potential
promote
tissue
regeneration
healing.
Herein,
a
comprehensive
review
multi‐functional
printing‐based
hydrogel
healing
is
presented.
The
first
summarizes
techniques
dressings,
including
photo‐curing,
extrusion,
inkjet,
laser‐assisted
printing.
Then,
properties
design
approaches
series
bioinks
composed
natural,
synthetic,
composite
polymers
described.
Thereafter,
application
in
variety
environments
discussed
depth,
hemostasis,
anti‐inflammation,
antibacterial,
skin
appendage
regeneration,
intelligent
monitoring,
machine
learning‐assisted
therapy.
Finally,
challenges
prospects
Language: Английский
Recent advances in bioactive wound dressings
Wound Repair and Regeneration,
Journal Year:
2024,
Volume and Issue:
33(1)
Published: Nov. 14, 2024
Abstract
Traditional
wound
dressings,
despite
their
widespread
use,
face
limitations,
such
as
poor
infection
control
and
insufficient
healing
promotion.
To
address
these
challenges,
bioactive
materials
have
emerged
a
promising
solution
in
care.
This
comprehensive
review
explores
the
latest
developments
technologies,
starting
with
an
overview
of
importance
effective
management,
emphasising
need
for
advanced
dressings.
The
further
various
materials,
defining
characteristics.
It
covers
wide
range
natural
synthetic
biopolymers
used
to
develop
Next,
paper
discusses
incorporation
agents
into
including
antimicrobial
anti‐inflammatory
agents,
alongside
regenerative
components
like
growth
factors,
platelet‐rich
plasma,
fibrin
stem
cells.
also
fabrication
techniques
highlighting
electrospinning,
which
facilitated
production
nanofibre‐based
dressings
controlled
porosity,
sol–gel
method
developing
glass‐based
3D
bioprinting
customised,
patient‐specific
concludes
by
addressing
challenges
future
perspectives
dressing
development.
includes
regulatory
considerations,
clinical
efficacy,
patient
care
protocol
integration
progress
monitoring.
Furthermore,
considers
emerging
trends
smart
sensors
personalised
medicine
approaches,
offering
insights
direction
research.
Language: Английский
3D Printing in Wound Healing: Innovations, Applications, and Future Directions
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 8, 2024
The
field
of
wound
healing
faces
significant
challenges,
particularly
in
the
treatment
chronic
wounds,
which
often
result
prolonged
times
and
complications.
Recent
advancements
3D
printing
technology
have
provided
innovative
solutions
to
these
offering
tailored
precise
approaches
care.
This
review
highlights
role
enhancing
healing,
focusing
on
its
application
creating
biocompatible
scaffolds,
custom
dressings,
drug
delivery
systems.
By
mimicking
extracellular
matrix
(ECM)
facilitating
cell
proliferation,
3D-printed
biomaterials
potential
significantly
accelerate
process.
In
addition,
bioprinting
enables
production
functional
skin
substitutes
that
can
be
customized
for
individual
patients.
Despite
promise
technologies,
several
challenges
remain,
including
need
improved
vascularization,
cost
concerns,
regulatory
hurdles.
future
lies
continued
integration
with
emerging
technologies
such
as
4D
bioelectronics,
providing
opportunities
personalized
on-demand
therapies.
explores
current
state
care,
technologies.
Language: Английский