Ochratoxin A in Food Commodities: A Review of Occurrence, Toxicity, and Management Strategies DOI Creative Commons
Joel Cox Menka Banahene, Isaac Williams Ofosu, Bernard Tawiah Odai

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(20), P. e39313 - e39313

Published: Oct. 1, 2024

Ochratoxin A (OTA) is a potent mycotoxin produced by species of Aspergillus and Penicillium that contaminate agricultural products pose significant health risks to both humans animals. This review examines the mechanisms OTA toxicity, its occurrence in various food commodities, implications for public trade. Literature pertaining was sourced from Google Scholar, covering period 2004 2024. exposure linked multiple adverse effects, including teratogenicity, immunotoxicity, hepatotoxicity, with primary impact on kidney function, it classified as possible human carcinogen (Group 2B). Its toxic effects are attributed several mechanisms, lipid peroxidation, inhibition protein synthesis, DNA damage, oxidative stress, mitochondrial dysfunction. Notable findings included presence 46.7 % cocoa Turkey, 32 samples Côte d'Ivoire exceeding threshold 2 μg/kg, 91.5 ready-to-sell beans Nigeria testing positive OTA. Coffee particularly susceptible contamination, which underscores need vigilant monitoring. Additionally, contamination impacts productivity safety, leading economic consequences, regions reliant exports, such coffee. Several countries regulate levels safeguard health. However, these regulations can impede trade, high contamination. Balancing regulatory compliance viability crucial affected nations. Current strategies managing include improved agronomic practices, use biocontrol agents pest management, enhanced storage conditions prevent mould growth, implementation detoxification techniques reduce products. Despite strategies, remains threat economy worldwide. The complexity requires robust prevention, control, management mitigate impact. Continuous research initiatives essential safeguarding consumers ensuring safety.

Language: Английский

Assessing the fungal contamination and potential impact of ochratoxigenic Aspergillus species on cocoa beans from cocoa-growing regions of Ghana DOI Creative Commons
Joel Cox Menka Banahene, Isaac Williams Ofosu, Herman Erick Lutterodt

et al.

Science Progress, Journal Year: 2025, Volume and Issue: 108(1)

Published: Jan. 1, 2025

Objective: This study investigated the fungal contamination profile of cocoa beans from cocoa-growing regions in Ghana, with particular emphasis on potential impact ochratoxigenic Aspergillus species. Methods: A total 104 fermented and dried were randomly collected farmers for analysis. Fungal isolation was conducted using potato dextrose agar malt extract media. Species-level identification performed through macroscopic microscopic techniques. Ochratoxin (OTA) quantification confirmation carried out high-performance liquid chromatography fluorescence detection chromatography-tandem mass spectrometry (LC-MS/MS). Results: The investigation revealed 163 isolates representing 14 distinct species across 10 genera. species, including flavus, niger, parasiticus, fumigatus, predominant. No statistically significant differences occurrence observed among different regions. However, certain exhibited preferential growth specific media, emphasizing importance medium selection mycological studies. Of tested, only niger demonstrated ability to produce OTA vitro, as confirmed by LC-MS/MS Conclusion: discovery holds substantial implications both industry public health, considering that is a potent mycotoxin subject strict regulatory limits food commodities. It crucial implement enhanced monitoring control measures mitigate beans, particularly targeting OTA-producing also highlights need improved post-harvest handling practices, optimized storage conditions, biocontrol approaches.

Language: Английский

Citations

0
Ochratoxin A in Food Commodities: A Review of Occurrence, Toxicity, and Management Strategies DOI Creative Commons
Joel Cox Menka Banahene, Isaac Williams Ofosu, Bernard Tawiah Odai

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(20), P. e39313 - e39313

Published: Oct. 1, 2024

Ochratoxin A (OTA) is a potent mycotoxin produced by species of Aspergillus and Penicillium that contaminate agricultural products pose significant health risks to both humans animals. This review examines the mechanisms OTA toxicity, its occurrence in various food commodities, implications for public trade. Literature pertaining was sourced from Google Scholar, covering period 2004 2024. exposure linked multiple adverse effects, including teratogenicity, immunotoxicity, hepatotoxicity, with primary impact on kidney function, it classified as possible human carcinogen (Group 2B). Its toxic effects are attributed several mechanisms, lipid peroxidation, inhibition protein synthesis, DNA damage, oxidative stress, mitochondrial dysfunction. Notable findings included presence 46.7 % cocoa Turkey, 32 samples Côte d'Ivoire exceeding threshold 2 μg/kg, 91.5 ready-to-sell beans Nigeria testing positive OTA. Coffee particularly susceptible contamination, which underscores need vigilant monitoring. Additionally, contamination impacts productivity safety, leading economic consequences, regions reliant exports, such coffee. Several countries regulate levels safeguard health. However, these regulations can impede trade, high contamination. Balancing regulatory compliance viability crucial affected nations. Current strategies managing include improved agronomic practices, use biocontrol agents pest management, enhanced storage conditions prevent mould growth, implementation detoxification techniques reduce products. Despite strategies, remains threat economy worldwide. The complexity requires robust prevention, control, management mitigate impact. Continuous research initiatives essential safeguarding consumers ensuring safety.

Language: Английский

Citations

3