To
review
the
theoretical
basis
and
therapeutic
effects
of
fecal
microbiota
transplantation
(FMT)
in
various
diseases
animal
experiments
clinical
studies,
as
well
limitations
current
standards
FMT
application.
PubMed
Web
Science
databases
were
searched
for
articles
published
only
English
between
1975
2023
on
reliable
results
treatment
FMT.
The
properties
gut
its
interactions
with
host
metabolism
are
critical
to
human
health,
microbiome
disturbance
is
closely
associated
intestinal
extra-intestinal
diseases.
Therefore,
tools
targeting
modulation
have
attracted
increasing
attention,
among
which
represents
most
widely
studied
intervention
strategy.
This
gathered
summarized
application
diseases,
metabolic
hypertension,
cancer,
nervous
system
arthritis,
elaborated
beneficial
that
can
be
achieved
by
altering
mechanisms
action.
In
addition,
potential
risks
side
approach
discussed,
efforts
standardize
development
Through
a
systemic
outcome
mechanism
we
aimed
provide
construction
an
optimized
framework,
so
better
exert
prospects.
Frontiers in Immunology,
Journal Year:
2025,
Volume and Issue:
16
Published: April 22, 2025
Metabolic
syndrome
(MetS)
is
a
group
of
symptoms
that
are
characterized
by
abnormal
changes
in
metabolic
substances
such
as
glucose,
lipids,
proteins,
and
bile
acids.
MetS
common
complication
after
organ
transplantation
can
further
affect
the
survival
physiological
function
graft
reprograming
patient’s
immune
environment.
Additionally,
influence
occurrence
post-transplant
complications,
infections.
In
recent
years,
research
into
epidemiology
mechanisms
has
grown
significantly.
this
review,
we
summarize
hyperglycemia,
insulin
resistance,
hyperlipidemia,
acids,
amino
acids
on
body’s
cells
related
to
effect
disorders
rejection
liver,
kidney,
heart,
skin
other
transplantation.
Finally,
provide
an
overview
current
treatment
strategies
offer
insights
potential
future
therapies
for
managing
transplant
recipients.
Frontiers in Endocrinology,
Journal Year:
2024,
Volume and Issue:
15
Published: Sept. 20, 2024
In
recent
years,
with
the
rapid
development
of
omics
technologies,
researchers
have
shown
that
interactions
between
intestinal
flora
and
bile
acids
are
closely
related
to
progression
diabetic
kidney
disease
(DKD).
By
regulating
acid
metabolism
receptor
expression,
affects
host
metabolism,
impacts
immune
system,
exacerbates
injury
in
DKD
patients.
To
explore
among
gut
flora,
DKD,
as
well
mechanisms,
depth,
this
paper,
we
review
existing
literature
on
correlations
DKD.
This
also
summarizes
efficacy
their
receptors
traditional
Chinese
medicines
treatment
highlights
unique
advantages
treatment.
paper
is
expected
reveal
a
new
important
potential
strategy
for
clinical
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 30, 2024
Cardiometabolic
syndrome
(CMS),
type
2
diabetes
mellitus
(T2DM),
and
cardiovascular
diseases
are
among
the
major
altruists
to
international
liability
of
disease.
The
lifestyle
dietary
changes
attributable
economic
growth
have
resulted
in
an
epidemiological
transition
towards
non-communicable
(NCDs)
as
leading
causes
death.
Low-
middle-income
countries
(LMICs)
bear
a
more
substantial
disease
burden
due
limited
healthcare
sector
capacities
address
rapidly
growing
number
chronic
patients.
purpose
this
narrative
review
paper
was
explore
interrelationships
between
CMS,
T2DM,
impairments
context
NCDs,
well
preventative
control
interventions.
role
insulin
resistance,
hyperglycemia,
dyslipidemia
pathogenesis
T2DM
development
severe
highlighted.
This
elaborated
on
pivotal
modifications,
such
healthy
diets
physical
activity,
cornerstones
addressing
epidemics
metabolic
diseases.
Foods
high
calories,
refined
sugar,
red
meat,
processed
ready-to-eat
meals
were
associated
with
amplified
risk
CMS
T2DM.
In
contrast,
based
fruits,
legumes,
vegetables,
whole
grain,
home-cooked
foods
demonstrated
protective
effects
against
Additionally,
psychological
behavioral
approach
highlighted,
especially
regarding
its
impact
patient
empowerment
patient-centered
therapeutic
To
review
the
theoretical
basis
and
therapeutic
effects
of
fecal
microbiota
transplantation
(FMT)
in
various
diseases
animal
experiments
clinical
studies,
as
well
limitations
current
standards
FMT
application.
PubMed
Web
Science
databases
were
searched
for
articles
published
only
English
between
1975
2023
on
reliable
results
treatment
FMT.
The
properties
gut
its
interactions
with
host
metabolism
are
critical
to
human
health,
microbiome
disturbance
is
closely
associated
intestinal
extra-intestinal
diseases.
Therefore,
tools
targeting
modulation
have
attracted
increasing
attention,
among
which
represents
most
widely
studied
intervention
strategy.
This
gathered
summarized
application
diseases,
metabolic
hypertension,
cancer,
nervous
system
arthritis,
elaborated
beneficial
that
can
be
achieved
by
altering
mechanisms
action.
In
addition,
potential
risks
side
approach
discussed,
efforts
standardize
development
Through
a
systemic
outcome
mechanism
we
aimed
provide
construction
an
optimized
framework,
so
better
exert
prospects.
