Oral and Oropharyngeal Microbiome – Characteristics, Significance, and Potential Therapeutic Interventions DOI

Laura Ziuzia-Januszewska,

Jakub Zygało,

Eliza Brożek-Mądry

et al.

Polski Przegląd Otorynolaryngologiczny, Journal Year: 2024, Volume and Issue: 13(4), P. 19 - 30

Published: Dec. 19, 2024

The proper functioning of the human body largely depends on microorganisms it hosts. ecosystem formed by these microorganisms, along with their genome, metabolites they produce, and conditions in environment, constitutes microbiome. microbiome plays a crucial role regulating host’s physiological, immunological, metabolic functions. Changes composition can affect occurrence progression both local oral cavity oropharynx, as well systemic diseases. Therefore, is essential to explore methods for modifying microbiome’s preventing negative consequences dysbiosis. Current research focuses probiotics, prebiotics, dietary supplements, antibiotics, chemotherapeutics. This review aims summarize knowledge regarding oropharyngeal microbiome, its significance health, potential therapeutic approaches influence this complex ecosystem.

Language: Английский

Oral and Oropharyngeal Microbiome – Characteristics, Significance, and Potential Therapeutic Interventions DOI

Laura Ziuzia-Januszewska,

Jakub Zygało,

Eliza Brożek-Mądry

et al.

Polski Przegląd Otorynolaryngologiczny, Journal Year: 2024, Volume and Issue: 13(4), P. 19 - 30

Published: Dec. 19, 2024

The proper functioning of the human body largely depends on microorganisms it hosts. ecosystem formed by these microorganisms, along with their genome, metabolites they produce, and conditions in environment, constitutes microbiome. microbiome plays a crucial role regulating host’s physiological, immunological, metabolic functions. Changes composition can affect occurrence progression both local oral cavity oropharynx, as well systemic diseases. Therefore, is essential to explore methods for modifying microbiome’s preventing negative consequences dysbiosis. Current research focuses probiotics, prebiotics, dietary supplements, antibiotics, chemotherapeutics. This review aims summarize knowledge regarding oropharyngeal microbiome, its significance health, potential therapeutic approaches influence this complex ecosystem.

Language: Английский

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