A systematic literature review to clarify the concept of vaccine hesitancy

Nature Human Behaviour, Journal Year: 2022, Volume and Issue: 6(12), P. 1634 - 1648

Published: Aug. 22, 2022

Language: Английский

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Predicting Vaccination Intention against COVID-19 Using Theory of Planned Behavior: A Systematic Review and Meta-Analysis

Vaccines, Journal Year: 2022, Volume and Issue: 10(12), P. 2026 - 2026

Published: Nov. 26, 2022

This study systematically analyzed the literature using theory of planned behavior (TPB) as a theoretical framework to examine influence its constructs on vaccination intention against COVID-19. Quantitative studies were searched in PubMed, CINAHL, Web Science, and Google Scholar following PRISMA guidelines. The average rate COVID-19 was 73.19%, ranging from 31% 88.86%. Attitude had strongest association with (r+ = 0.487, 95% CI: 0.368–0.590), followed by subjective norms 0.409, 0.300–0.507), perceived behavioral control 0.286, 0.198–0.369). Subgroup analyses showed that pooled effect sizes TPB varied across geographic regions populations. large Asia, Europe, Oceania, especially among adult general population, parents, patients. Subjective Asia parents Perceived most dominant predictor acceptance Africa These findings suggest provides useful for predicting receive vaccine. Hence, public awareness educational programs aimed at promoting should consider achieve goal.

Language: Английский

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Healthcare Workers after Two Years of COVID-19: The Consequences of the Pandemic on Psychological Health and Sleep among Nurses and Physicians

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(2), P. 1410 - 1410

Published: Jan. 12, 2023

COVID-19 has challenged the health workforce worldwide. In this cross-sectional study with a retrospective assessment, we explored impact of pandemic on mental and sleep among sample Italian nurses medical doctors. A total 287 healthcare workers (212 75 physicians) completed web survey socio-demographic, psychological, sleep-related aspects referring to period before present February June 2022. Comparisons between physicians revealed that former had greater distress in response pandemic. Consistently, multivariate analysis covariance showed even if both groups were negatively impacted by pandemic, presented worsening over time regarding several psychological symptoms. Furthermore, observed working frontline represented an additional risk factor for nurses. line previous evidence, also found personal experiences are significant predictors current status. Our results underscore urgent need preventive programs operators increase their coping skills prevent long-term consequences chronic stress, especially high-risk professionals. Specific attention should be devoted improve quality reduce traumatic

Language: Английский

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COVID-19 vaccine hesitancy: a systematic review of barriers to the uptake of COVID-19 vaccine among adults in Nigeria

Bulletin of the National Research Centre/Bulletin of the National Research Center, Journal Year: 2023, Volume and Issue: 47(1)

Published: March 21, 2023

Abstract Background Since the outbreak of coronavirus (COVID-19) disease was reported in 2019, huge human and material resources have been expended globally to combat spread disease. Achieving herd immunity through mass vaccination remains an important strategy adopt war against this since it is practically impossible for 60–70% population achieve natural infection alone. Unfortunately, there widespread reports COVID-19 vaccine hesitancy. This study aims systematically review literature provide up-to-date assessment acceptance rates also explore factors impacting hesitancy among adults Nigeria. Main body abstract A systematic search indexed electronic peer-reviewed published from 2019 onwards conducted Science Direct, PubMed, ProQuest, EBSCOhost databases according PRISMA checklist Synthesis without meta-analysis (SWiM) reporting guidelines. Fifteen out 148 studies retrieved, met inclusion criteria these were critically appraised using Centre Evidence-Based Medicine Critical Appraisal Mixed Methods Tool, version 2018. Basic descriptive statistic (percentage) employed analysis various subgroups Nigeria, while a thematic facilitators barriers uptake Nigeria conducted. Acceptance ranging 24.3% 49.5% observed across four high-risk populations low-risk ranged 26.0% 86.2%. Themes such as socio-demographic factors, perception risk concerns about vaccine's safety efficacy act interchangeably vaccines, whereas political conspiracy theories, cost primarily uptake. Short conclusion Substantial heterogeneity More than half reviewed below 60.0%. multidisciplinary approach recommended engaging stakeholders, effectively address

Language: Английский

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Hesitancy about COVID-19 vaccination among pregnant women: a cross-sectional study based on the health belief model

BMC Pregnancy and Childbirth, Journal Year: 2022, Volume and Issue: 22(1)

Published: Aug. 2, 2022

Pregnant women are at high risk for affliction by coronavirus disease 2019 (COVID-19). Vaccination is a main strategy to prevent and manage the COVID-19 pandemic. However, hesitancy about vaccination (HACV) major public health threat barrier herd immunity. The aim of study was evaluate pregnant women's HACV based on Health Belief Model (HBM).This cross-sectional conducted in 2021-2022. Participants were 352 selected from several healthcare centers north Iran. Instruments data collection demographic questionnaire, Knowledge Questionnaire, question HACV. Logistic regression analysis used assess effects variables HACV.The rate 42.61%. In model, three factors perceived benefits (aOR: 0.700; 95% CI: 0.594 0.825), cues action 0.621; 0.516 0.574), history reproductive problems 2.327; 0.1.262 4.292) had significant (P < 0.001).HACV highly prevalent among women. components HBM have HACV, while component has no effect it. good model explain Educational interventions necessary improve awareness risks them their fetus.

Language: Английский

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COVID-19 vaccine hesitancy worldwide and its associated factors: a systematic review and meta-analysis

Science in One Health, Journal Year: 2023, Volume and Issue: 2, P. 100048 - 100048

Published: Jan. 1, 2023

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has taken a toll on humans, and the development of effective vaccines been promising tool to end pandemic. However, for vaccination program be successful, considerable proportion community must vaccinated. Hence, public acceptance COVID-19 become key controlling Recent studies have shown vaccine hesitancy increasing over time. This systematic review aims evaluate rate related factors in different communities. A comprehensive search was performed Medline (via PubMed), Scopus, Web Science from January 1, 2019 31, 2022. All relevant descriptive observational (cross-sectional longitudinal) were included this review. In meta-analysis, Odds Ratio (OR) used assess effects population characteristics hesitancy, event (acceptance rate) effect measure overall acceptance. Publication bias assessed using funnel plot, Egger's test, trim-and-fill methods. total 135 out 6,417 after screening. meta-analysis 114 studies, including 849,911 participants, showed an 63.1%. addition, men, married individuals, educated people, those with history flu vaccination, higher income levels, comorbidities, people living urban areas less hesitant. Increasing awareness importance overcoming is crucial. Being region, being or educated, having influenza level status, comorbidities are associated

Language: Английский

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Determinants of parental seasonal influenza vaccine hesitancy in the Eastern Mediterranean region: A cross-sectional study

Frontiers in Public Health, Journal Year: 2023, Volume and Issue: 11

Published: March 28, 2023

Background Seasonal influenza vaccine can reduce the risk of influenza-associated hospitalizations and deaths among children. Given that parents are primary decision makers, this study examined parental attitude toward childhood identified determinants hesitancy (VH) in Eastern Mediterranean region (EMR). Methods A cross-sectional was conducted using an anonymous online survey 14 EMR countries. Parents children aged 6 months to 18 years were included. The Parent Attitude about Childhood Vaccines (PACV) used assess VH. Chi square test independent t-test for association qualitative quantitative variables, respectively. structural equations model (SEM) identify direct indirect Results Almost half hesitant vaccinating their against (50.8%). Parental VH significantly higher older mothers (37.06 ± 8.8 years, p = 0.006), rural residents (53.6%, &lt; 0.001), high-income countries (50.6%, with educational levels (52.1%, 0.001). school-aged (5–9 years) (55.6%, free from any comorbidities (52.5%, who did not receive routine vaccination at all (51.5%, 0.03), vaccinated COVID-19 (54.3%, addition (57.1%, 0.001) associated increased likelihood depending on healthcare provider as a source information regarding vaccines less likely report (47.9%, meanwhile those social media health showed (57.2%, SEM suggested mother’s age, residence, country income level, child gender, total number had effect Meanwhile, influenza, completely or partially Coronavirus disease 2019 (COVID-19) Conclusion high proportion included vaccinate seasonal influenza. This is due many modifiable non-modifiable factors be targeted improve coverage.

Language: Английский

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Application of Traditional Vaccine Development Strategies to SARS-CoV-2

mSystems, Journal Year: 2023, Volume and Issue: 8(2)

Published: March 2, 2023

Over the past 150 years, vaccines have revolutionized relationship between people and disease. During COVID-19 pandemic, technologies such as mRNA received attention due to their novelty successes. However, more traditional vaccine development platforms also yielded important tools in worldwide fight against SARS-CoV-2 virus. A variety of approaches been used develop that are now authorized for use countries around world. In this review, we highlight strategies focus on viral capsid outwards, rather than nucleic acids inside. These fall into two broad categories: whole-virus subunit vaccines. Whole-virus virus itself, either an inactivated or attenuated state. Subunit contain instead isolated, immunogenic component Here, candidates apply these different ways. a companion manuscript, review recent novel nucleic-acid based technologies. We further consider role programs played prophylaxis at global scale. Well-established proved especially making accessible low- middle-income countries. Vaccine established undertaken much wider range those using nucleic-acid-based technologies, which led by wealthy Western Therefore, platforms, though less from biotechnological standpoint, proven be extremely management SARS-CoV-2.

Language: Английский

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Effectiveness of chatbots on COVID vaccine confidence and acceptance in Thailand, Hong Kong, and Singapore

npj Digital Medicine, Journal Year: 2023, Volume and Issue: 6(1)

Published: May 25, 2023

Chatbots have become an increasingly popular tool in the field of health services and communications. Despite chatbots' significance amid COVID-19 pandemic, few studies performed a rigorous evaluation effectiveness chatbots improving vaccine confidence acceptance. In Thailand, Hong Kong, Singapore, from February 11th to June 30th, 2022, we conducted multisite randomised controlled trials (RCT) on 2,045 adult guardians children seniors who were unvaccinated or had delayed vaccinations. After week using chatbots, differences acceptance compared between intervention control groups. Compared non-users, fewer chatbot users reported decreased Thailand child group [Intervention: 4.3 % vs. Control: 17%, P = 0.023]. However, more [26% 12%, 0.028] Kong safety [29% 10%, 0.041] Singapore group. There was no statistically significant change senior Employing RE-AIM framework, process indicated strong implementation support for stakeholders, with high levels sustainability scalability. This multisite, parallel RCT study found mixed success among Asian subpopulations. Further that link usage real-world uptake are needed augment evidence employing advance

Language: Английский

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Respiratory syncytial virus immunoprophylaxis: Novel opportunities and a call for equity

Journal of Medical Virology, Journal Year: 2024, Volume and Issue: 96(2)

Published: Feb. 1, 2024

Abstract With the approval of first vaccines against respiratory syncytial virus (RSV) and a novel RSV‐neutralizing antibody, 2023 has been perceived as game‐changing year in preventing severe outcomes RSV infections infants elderly. However, costs these pharmaceuticals are high, while disproportionately impacts populations low‐to‐middle‐income regions, which may continue to suffer from lack pharmaceutical measures for prevention under health socioeconomic disparities. This paper presents an overview characteristics, clinical results, status various anti‐RSV antibodies. It posits that wealthy nations cannot monopolize immunoprophylaxis should work jointly make it available lower‐income countries. An approach toward equity based on five points is offered: (1) integration antibodies into existing global humanitarian distribution systems, (2) using affordable vaccine pricing models, (3) enforcing part national public strategy, (4) implementing equitable allocation frameworks immunoprophylaxis, (5) promoting local manufacturing. Such plan needs be put action soon possible avoid delays serving with highest related burden.

Language: Английский

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