Unraveling the secrets: Evolution of resistance mediated by membrane proteins DOI Creative Commons
Xue Yang, Min Li,

Zi-Chang Jia

et al.

Drug Resistance Updates, Journal Year: 2024, Volume and Issue: 77, P. 101140 - 101140

Published: Aug. 16, 2024

Membrane protein-mediated resistance is a multidisciplinary challenge that spans fields such as medicine, agriculture, and environmental science. Understanding its complexity devising innovative strategies are crucial for treating diseases like cancer managing resistant pests in agriculture. This paper explores the dual nature of mechanisms across different organisms: On one hand, animals, bacteria, fungi, plants, insects exhibit convergent evolution, leading to development similar mechanisms. other influenced by diverse pressures structural differences among organisms, they also demonstrate divergent characteristics. prevalent insects, reflecting their shared survival evolved through evolution address challenges. However, variations ecological environments biological characteristics result differing responses resistance. Therefore, examining these not only enhances our understanding adaptive but provides theoretical support insights addressing drug advancing pharmaceutical development.

Language: Английский

Unraveling the secrets: Evolution of resistance mediated by membrane proteins DOI Creative Commons
Xue Yang, Min Li,

Zi-Chang Jia

et al.

Drug Resistance Updates, Journal Year: 2024, Volume and Issue: 77, P. 101140 - 101140

Published: Aug. 16, 2024

Membrane protein-mediated resistance is a multidisciplinary challenge that spans fields such as medicine, agriculture, and environmental science. Understanding its complexity devising innovative strategies are crucial for treating diseases like cancer managing resistant pests in agriculture. This paper explores the dual nature of mechanisms across different organisms: On one hand, animals, bacteria, fungi, plants, insects exhibit convergent evolution, leading to development similar mechanisms. other influenced by diverse pressures structural differences among organisms, they also demonstrate divergent characteristics. prevalent insects, reflecting their shared survival evolved through evolution address challenges. However, variations ecological environments biological characteristics result differing responses resistance. Therefore, examining these not only enhances our understanding adaptive but provides theoretical support insights addressing drug advancing pharmaceutical development.

Language: Английский

Citations

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