Developing biotechnologies in organoids for liver cancer DOI Creative Commons
Yi Hu, Peng Zheng,

Mengdi Qiu

et al.

Biomedical Technology, Journal Year: 2024, Volume and Issue: 9, P. 100067 - 100067

Published: Nov. 26, 2024

Language: Английский

The cutting‐edge progress in bioprinting for biomedicine: principles, applications, and future perspectives DOI Creative Commons
Shuge Liu, Yating Chen,

Zhiyao Wang

et al.

MedComm, Journal Year: 2024, Volume and Issue: 5(10)

Published: Sept. 23, 2024

Bioprinting is a highly promising application area of additive manufacturing technology that has been widely used in various fields, including tissue engineering, drug screening, organ regeneration, and biosensing. Its primary goal to produce biomedical products such as artificial implant scaffolds, tissues organs, medical assistive devices through software-layered discrete numerical control molding. Despite its immense potential, bioprinting still faces several challenges. It requires concerted efforts from researchers, engineers, regulatory bodies, industry stakeholders are principal overcome these challenges unlock the full potential bioprinting. This review systematically discusses principles, applications, future perspectives while also providing topical overview research progress over past two decades. The most recent advancements comprehensively reviewed here. First, printing techniques methods summarized along with related bioinks supporting structures. Second, interesting representative cases regarding applications biosensing introduced detail. Finally, remaining suggestions for directions proposed discussed. one areas fields. aims devices. perspectives, which provides description

Language: Английский

Citations

4

Advanced tumor organoid bioprinting strategy for oncology research DOI Creative Commons

Xiangran Cui,

Jianhang Jiao, Lili Yang

et al.

Materials Today Bio, Journal Year: 2024, Volume and Issue: 28, P. 101198 - 101198

Published: Aug. 9, 2024

Bioprinting is a groundbreaking technology that enables precise distribution of cell-containing bioinks to construct organoid models accurately reflect the characteristics tumors

Language: Английский

Citations

2

Integrating 3D Bioprinting and Organoids to Better Recapitulate the Complexity of Cellular Microenvironments for Tissue Engineering DOI Open Access
Yan Hu,

Tong Zhu,

Haitao Cui

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 8, 2024

Abstract Organoids, with their capacity to mimic the structures and functions of human organs, have gained significant attention for simulating pathophysiology been extensively investigated in recent past. Additionally, 3D bioprinting, as an emerging bio‐additive manufacturing technology, offers potential constructing heterogeneous cellular microenvironments, thereby promoting advancements organoid research. In this review, latest developments bioprinting technologies aimed at enhancing engineering are introduced. The commonly used methods materials organoids, a particular emphasis on advantages combining organoids summarized. These include achieving high cell concentrations form large aggregates, precise deposition building blocks create complex functions, automation throughput ensure reproducibility standardization culture. Furthermore, review provides overview relevant studies from years discusses current limitations prospects future development.

Language: Английский

Citations

2

3D‐Bioprinting for Precision Microtissue Engineering: Advances, Applications, and Prospects DOI
Jinrun Liu, Qi Wang,

Yinpeng Le

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 8, 2024

Abstract Microtissues, engineered to emulate the complexity of human organs, are revolutionizing fields regenerative medicine, disease modelling, and drug screening. Despite promise traditional microtissue engineering, it has yet achieve precision required fully replicate organ‐like structures. Enter 3D bioprinting, a transformative approach that offers unparalleled control over microtissue's spatial arrangement mechanical properties. This cutting‐edge technology enables detailed layering bioinks, crafting microtissues with tissue‐like It allows for direct construction organoids fine‐tuning forces vital tissue maturation. Moreover, 3D‐printed devices provide necessary guidance microenvironments, facilitating sophisticated interactions. The applications expanding rapidly, successful demonstrations their functionality in vitro vivo. excels at replicating intricate processes development, offering more ethical controlled alternative animal models. By simulating vivo conditions, emerging as powerful tools personalized screening, new avenues pharmaceutical development medicine.

Language: Английский

Citations

2

The Biological Macromolecules constructed Matrigel for cultured organoids in biomedical and tissue engineering DOI Creative Commons
Kai Zhao,

Yu Du,

Huimin Cao

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 247, P. 114435 - 114435

Published: Dec. 7, 2024

Language: Английский

Citations

1

Developing biotechnologies in organoids for liver cancer DOI Creative Commons
Yi Hu, Peng Zheng,

Mengdi Qiu

et al.

Biomedical Technology, Journal Year: 2024, Volume and Issue: 9, P. 100067 - 100067

Published: Nov. 26, 2024

Language: Английский

Citations

0