Neuropsychological consequences and sleep disorders in mild traumatic brain injury: pathomechanisms, diagnostic approaches and literature review DOI Creative Commons
K.S. Sarazhyna

Psychiatry Neurology and Medical Psychology, Journal Year: 2024, Volume and Issue: 26, P. 438 - 446

Published: Dec. 30, 2024

Background. During wartime, the incidence of mild traumatic brain injury (mTBI) has significantly increased among both military personnel and civilians. These injuries are often accompanied by neuropsychological disorders, including depression, anxiety, emotional lability, sleep disturbances. Purpose – this study aims to analyze impact mTBI on sleep, emotional, behavioral functioning. To identify pathophysiological mechanisms behind disorders disturbances, along with diagnostic approaches for their detection. Materials Methods. The article presents a bibliographic systematic review data from PubMed, Scopus, Web Science development as well psychiatric conditions. Results. Key underlying these include changes in neurotransmitter regulation, dysfunction prefrontal cortex, structural damage hippocampus amygdala. relationship between sleepdisturbances, state, functioning been characterized, highlighting decision-making, social adaptation, patient’s quality life. Conclusions. Further research should focus developing effective screening methods diagnosis wartime conditions, allowing prompt interventionand improving rehabilitation outcomes.

Language: Английский

Effects of Traumatic Brain Injury on the Orexin/Hypocretin System DOI Creative Commons
Rebecca T. Somach, Miranda M. Lim, Akiva S. Cohen

et al.

Neurotrauma Reports, Journal Year: 2025, Volume and Issue: 6(1), P. 322 - 335

Published: Jan. 1, 2025

Traumatic Brain Injuries (TBIs) are known to cause a myriad of symptoms in patients. One common symptom after injury is sleep disruptions. neuropeptide system has been studied repeatedly as potential disruptions TBI- the orexin/hypocretin system. Orexin promotes wakefulness and arousal while disrupting orexin causes increased sleepiness narcolepsy. Studies TBI human animal subjects have shown that affects This review serves an overview how system, including structural functional changes neurons injury. first include studies examine receptors. also examines sex accounted for TBI.

Language: Английский

Citations

0
Characteristics and Neural Mechanisms of Sleep–Wake Disturbances After Traumatic Brain Injury DOI

Guizhong Yan,

W. Yuan, Dengfeng Wang

et al.

Journal of Neurotrauma, Journal Year: 2024, Volume and Issue: 41(15-16), P. 1813 - 1826

Published: March 18, 2024

Sleep

Language: Английский

Citations

0
Neuropsychological consequences and sleep disorders in mild traumatic brain injury: pathomechanisms, diagnostic approaches and literature review DOI Creative Commons
K.S. Sarazhyna

Psychiatry Neurology and Medical Psychology, Journal Year: 2024, Volume and Issue: 26, P. 438 - 446

Published: Dec. 30, 2024

Background. During wartime, the incidence of mild traumatic brain injury (mTBI) has significantly increased among both military personnel and civilians. These injuries are often accompanied by neuropsychological disorders, including depression, anxiety, emotional lability, sleep disturbances. Purpose – this study aims to analyze impact mTBI on sleep, emotional, behavioral functioning. To identify pathophysiological mechanisms behind disorders disturbances, along with diagnostic approaches for their detection. Materials Methods. The article presents a bibliographic systematic review data from PubMed, Scopus, Web Science development as well psychiatric conditions. Results. Key underlying these include changes in neurotransmitter regulation, dysfunction prefrontal cortex, structural damage hippocampus amygdala. relationship between sleepdisturbances, state, functioning been characterized, highlighting decision-making, social adaptation, patient’s quality life. Conclusions. Further research should focus developing effective screening methods diagnosis wartime conditions, allowing prompt interventionand improving rehabilitation outcomes.

Language: Английский

Citations

0