Association of intrinsic capacity with functional decline and mortality in older adults: a systematic review and meta-analysis of longitudinal studies
The Lancet Healthy Longevity,
Journal Year:
2024,
Volume and Issue:
5(7), P. e480 - e492
Published: June 27, 2024
Language: Английский
Intrinsic capacity and recent falls in adults 80 years and older living in the community: results from the ilSIRENTE Study
Aging Clinical and Experimental Research,
Journal Year:
2024,
Volume and Issue:
36(1)
Published: Aug. 10, 2024
Abstract
Background
Falls
in
older
adults
significantly
impact
overall
health
and
healthcare
costs.
Intrinsic
capacity
(IC)
reflects
functional
reserve
is
an
indicator
of
healthy
aging.
Aims
To
explore
the
association
between
IC
recent
falls
(≤
90
days)
community-dwelling
octogenarians
from
Aging
Longevity
Sirente
geographic
area
(IlSIRENTE)
study.
Methods
The
Minimum
Data
Set
for
Home
Care
(MDS−HC)
supplementary
questionnaires
tests
were
used
to
assess
five
domains:
locomotion,
cognition,
vitality,
psychology,
sensory.
Scores
each
domain
rescaled
using
percent
maximum
possible
score
method
averaged
obtain
(range
0−100).
Results
study
included
319
participants
(mean
age
85.5
±
4.8
years,
67.1%
women).
Mean
was
80.5
14.2.
optimal
cut-off
predicting
two-year
risk
incident
loss
at
least
one
activity
daily
living
(ADL)
determined
validated
a
subset
240
individuals
without
ADL
disability
baseline
84.7
4.4
Participants
then
stratified
into
low
(<
77.6)
high
(≥
categories.
Those
with
(63.9%)
younger,
more
often
males,
had
lower
prevalence
falls,
disability,
multimorbidity,
polypharmacy.
Logistic
regression
models
including
as
continuous
variable
revealed
significant
higher
odds
falls.
This
unadjusted
(odds
ratio
[OR]
0.96,
95%
confidence
interval
[CI]
0.94–0.98,
p
<
0.001),
age-
sex-adjusted
(OR
CI
fully
adjusted
0.93–0.99,
=
0.003).
When
considering
categorical
variable,
logistic
showed
strong
0.31,
0.16–0.60,
0.001).
remained
both
0.30,
0.15–0.59,
0.001)
0.33,
0.16–0.82,
0.007).
locomotion
independently
associated
0.98,
0.97–0.99,
0.97,
0.96–0.99,
model
Discussion
first
MDS−HC-derived
instrument
IC.
Individuals
less
likely
report
being
domain.
Conclusions
Lower
linked
increased
Interventions
maintain
improve
IC,
especially
domain,
may
reduce
fall
octogenarians.
Language: Английский
Umbrella Review of Nonpharmacological Interventions for Intrinsic Capacity in Older Adults
Yu‐Tai Lo,
No information about this author
Hui‐Chen Su,
No information about this author
Chanisara Chuenchomnoy
No information about this author
et al.
Ageing Research Reviews,
Journal Year:
2025,
Volume and Issue:
unknown, P. 102742 - 102742
Published: April 1, 2025
Language: Английский
The Longitudinal Aging Study Amsterdam: design and cohort update 2025
European Journal of Epidemiology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 14, 2025
Language: Английский
Fragilidad y capacidad intrínseca; del concepto teórico a la aplicabilidad clínica
Juan Manuel Pérez-Castejón,
No information about this author
Francesç Formiga
No information about this author
Revista Española de Geriatría y Gerontología,
Journal Year:
2024,
Volume and Issue:
59(5), P. 101483 - 101483
Published: March 29, 2024
The development of intrinsic capacity measures for longitudinal research: The Longitudinal Aging Study Amsterdam
Experimental Gerontology,
Journal Year:
2024,
Volume and Issue:
197, P. 112599 - 112599
Published: Oct. 9, 2024
The
World
Health
Organization
has
introduced
the
construct
of
intrinsic
capacity
(IC)
as
an
important
component
healthy
ageing
and
overall
well-being
in
older
adults
present
study
aimed
to
develop
domain-specific
composite
IC
scores
validate
these
by
examining
their
longitudinal
relation
with
functioning.
Language: Английский
Intrinsic capacity loss rates and protective factors among individuals aged 80 years and older in Chinese nursing homes: A latent class analysis
Linlin Ma,
No information about this author
Enjie Zheng,
No information about this author
Yi Fang
No information about this author
et al.
Geriatric Nursing,
Journal Year:
2024,
Volume and Issue:
60, P. 42 - 51
Published: Aug. 31, 2024
Prior
to
this
cross-sectional
study,
the
intrinsic
capacity
(IC)
loss
rates
and
protective
factors
in
nursing
homes
for
individuals
aged
80
older
remained
unexplored.
Analysing
434
participants,
study
found
86.9
%
of
experienced
at
least
one
IC
domain,
with
detailed
losses
locomotion,
vision,
vitality,
hearing,
psychological,
cognitive
capacities
83.2
%,
52.8
50.9
46.5
44.9
44.0
respectively.
Following
latent
class
analysis
(LCA),
five
distinct
impairment
patterns
were
noted,
locomotor
emerging
as
a
central
component
across
most
classes.
persons
years
included
financial
stability,
being
male
or
younger
within
cohort,
junior
high
school
higher
education,
married,
no
smoking
history,
manageable
comorbidity
levels,
minimal
medication
use,
good
sleep,
not
using
assistive
devices.
Based
on
these
classes,
provides
potential
practical
framework
alongside
recommendations
care
strategies
oldest-old,
emphasising
importance
function
maintaining
overall
IC.
Language: Английский
Understanding individual differences in happiness sources using open datasets: Exploring implications for health technology design (Preprint)
JMIR Formative Research,
Journal Year:
2024,
Volume and Issue:
9, P. e65658 - e65658
Published: Dec. 18, 2024
Background
Psychologists
have
developed
frameworks
to
understand
many
constructs,
which
subsequently
informed
the
design
of
digital
mental
health
interventions
(DMHIs)
aimed
at
improving
outcomes.
The
science
happiness
is
one
such
domain
that
holds
significant
applied
importance
due
its
links
well-being
and
evidence
can
be
cultivated
through
interventions.
However,
as
with
unique
ways
in
individuals
experience
present
major
challenges
for
designing
personalized
DMHIs.
Objective
This
paper
aims
(1)
an
analysis
how
sex
may
interact
age,
marital
status,
parental
status
predict
individual
differences
sources
happiness,
(2)
a
preliminary
discussion
open
datasets
contribute
process
health-related
technology
innovations.
Methods
HappyDB
database
100,535
statements
what
people
consider
made
them
happy,
some
asking
past
24
hours
(49,831
statements)
considering
last
3
months
(50,704
statements).
Demographic
information
also
provided.
Binary
logistic
regression
analyses
are
used
determine
whether
various
groups
differed
their
likelihood
selecting
or
not
category
source
happiness.
Results
Sex
age
interacted
influence
was
selected
patterns
being
less
consistent
among
female
comparison
male
individuals.
For
were
predominantly
between
married
those
who
divorced
separated,
but
these
same
both
sexes.
Married,
single,
widowed
all
largely
similar
each
categories
there
anomalies,
appeared
important
anomalies.
Conclusions
interacts
reporting
affection,
bonding,
leisure,
achievement,
enjoying
moment
contribution
dataset
understanding
discussed
terms
potential
role
addressing
DMHIs
ethical,
responsible,
based,
acceptable,
engaging,
inclusive,
effective
users.
considers
content
general
benefit
from
exploring
new
methods
by
diverse
data
sources.
It
proposed
examining
extent
insights
nondigital
settings
inform
requirements
gathering
warranted.
Language: Английский
Value shift in response to aging: A longitudinal study based on healthy aging
Yiran Shen,
No information about this author
Xinjiao Cheng,
No information about this author
Xue Sang
No information about this author
et al.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 27, 2024
Abstract
Objective
Healthy
aging
is
considered
an
effective
way
to
deal
with
the
challenges
of
aging.
Intrinsic
capacity(IC)
and
functional
ability
(FA)
are
key
elements
this
concept.
However,
relationship
between
two
has
not
been
explored
in
detail.
Methods
A
theoretical
model
was
constructed
by
analyzing
concept
“health
quantification.”
national
database
(China
Health
Retirement
Longitudinal
Study,
CHARLS)
used
as
data
source
for
study.
range
physical
mental
measures
were
employed
construct
intrinsic
abilities
using
factor
analysis,
a
measure
disability
proxy
FA.
Descriptive
regression
analyses
also
conducted
preliminarily
assess
distribution
variables
on
IC).
This
study
cross-lagged
models
examine
structural
effect
differences
IC
FA
longitudinal
manner,
along
mediation
analysis
analyze
mechanism
two.
Results
showed
normal
increasing
trend
education
income.
In
indicate
significant
effects
direction.
The
greater
than
that
IC;
such
tends
intensify
over
time.
Furthermore,
multimorbidity
mediates
FA,
but
mediating
very
large.
Finally,
social
participation
did
significantly
mediate
IC.
Conclusion
provides
novel
insights
into
evolution
disability,
which
discovery
disease
only
process
outcome
disability.
suggests
policymakers
should
focus
identifying
disease,
assessing,
maintaining,
providing
intervention
before
disease.
authorities
promote
implementation
people-centered
rather
disease-centered
health
delivery
system
achieve
value
transformation.
Language: Английский
Sensitivity and Specificity of Three Measures of Intrinsic Capacity in Older People Aged 80 and Over in Nursing Homes
Linlin Ma,
No information about this author
Enjie Zheng,
No information about this author
Yi Fang
No information about this author
et al.
Clinical Interventions in Aging,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 2179 - 2194
Published: Dec. 1, 2024
Intrinsic
capacity
(IC),
a
crucial
indicator
for
the
United
Nations
Decade
of
Healthy
Ageing
2021-2030,
is
defined
by
WHO
as
foundation
functional
ability,
representing
composite
all
physical
and
mental
capacities
an
individual.
IC
spans
five
function
domains:
Locomotor,
psychological,
cognitive,
vitality,
sensory
(including
vision
hearing).
Accurate
assessment
vital
effective
interventions,
yet
comparative
analyses
these
tools
are
scarce.
Consequently,
we
evaluated
diagnostic
accuracy
three
in
individuals
aged
80
above-Integrated
care
older
people
(ICOPE)
Step
1,
ICOPE
2,
Lopez-Ortiz's
scoring
system.
This
cross-sectional
analysis
included
total
475
participants
≥80
years
between
July
2023
January
2024
11
nursing
homes
Ningbo,
Zhejiang
Province,
China.
To
assess
that
sociodemographic
health-related
information
alongside
tools.
Diagnostic
efficacy
was
gauged
using
sensitivity,
specificity,
negative
predictive
value
(NPV),
positive
(PPV),
accuracy,
Youden
index,
area
under
curve
(AUC).
The
detection
decline
exceeded
85%
across
methods.
Using
2
benchmark,
1
showed
robust
performance
four
domains
locomotion,
whereas
system
generally
ineffective.
All
methods
have
limitations.
save
resources,
can
be
considered
direct
non-sensory
domains.
Conversely,
systems
exhibited
overly
stringent
lenient
thresholds,
respectively.
At
this
stage,
cannot
balance
subjectivity
objectivity;
thus,
it
recommended
appropriate
tool
selected
according
to
actual
application
scenarios.
Continuous
improvement
remains
requirement
future
studies.
Language: Английский