Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in adults DOI
Mikashmi Kohli,

Ian Schiller,

Nandini Dendukuri

et al.

Cochrane library, Journal Year: 2021, Volume and Issue: 2021(1)

Published: Jan. 15, 2021

Language: Английский

Tuberculosis DOI Open Access
Madhukar Pai, Marcel A. Behr, David W. Dowdy

et al.

Nature Reviews Disease Primers, Journal Year: 2016, Volume and Issue: 2(1)

Published: Oct. 27, 2016

Language: Английский

Citations

1004

Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline DOI Open Access
Charles L. Daley, Jonathan M. Iaccarino, Christoph Lange

et al.

Clinical Infectious Diseases, Journal Year: 2020, Volume and Issue: 71(4), P. 905 - 913

Published: Aug. 14, 2020

Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans all ages affect both pulmonary extrapulmonary sites. This guideline focuses on adults (without cystic fibrosis or human immunodeficiency virus infection) caused by the most common NTM pathogens such as Mycobacterium avium complex, kansasii, xenopi among slowly growing abscessus rapidly NTM. A panel experts was carefully selected leading international respiratory medicine infectious diseases societies (ATS, ERS, ESCMID, IDSA) included specialists medicine, clinical microbiology, laboratory patient advocacy. Systematic reviews were conducted around each 22 PICO (Population, Intervention, Comparator, Outcome) questions recommendations formulated, written, graded using GRADE (Grading Recommendations Assessment, Development, Evaluation) approach. Thirty-one evidence-based about treatment are provided. is intended for use healthcare professionals who care patients with disease, including diseases.

Language: Английский

Citations

656

Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline DOI Open Access
Charles L. Daley, Jonathan M. Iaccarino, Christoph Lange

et al.

European Respiratory Journal, Journal Year: 2020, Volume and Issue: 56(1), P. 2000535 - 2000535

Published: July 1, 2020

Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans all ages affect both pulmonary extrapulmonary sites. This guideline focuses on adults (without cystic fibrosis or human immunodeficiency virus infection) caused by the most common NTM pathogens such as Mycobacterium avium complex, kansasii , xenopi among slowly growing abscessus rapidly NTM. A panel experts was carefully selected leading international respiratory medicine infectious diseases societies (ATS, ERS, ESCMID, IDSA) included specialists medicine, clinical microbiology, laboratory patient advocacy. Systematic reviews were conducted around each 22 PICO (Population, Intervention, Comparator, Outcome) questions recommendations formulated, written, graded using GRADE (Grading Recommendations Assessment, Development, Evaluation) approach. Thirty-one evidence-based about treatment are provided. is intended for use healthcare professionals who care patients with disease, including diseases.

Language: Английский

Citations

608

Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline DOI Open Access
Charles L. Daley, Jonathan M. Iaccarino, Christoph Lange

et al.

Clinical Infectious Diseases, Journal Year: 2020, Volume and Issue: 71(4), P. e1 - e36

Published: March 6, 2020

Abstract Nontuberculous mycobacteria (NTM) represent over 190 species and subspecies, some of which can produce disease in humans all ages affect both pulmonary extrapulmonary sites. This guideline focuses on adults (without cystic fibrosis or human immunodeficiency virus infection) caused by the most common NTM pathogens such as Mycobacterium avium complex, kansasii, xenopi among slowly growing abscessus rapidly NTM. A panel experts was carefully selected leading international respiratory medicine infectious diseases societies (ATS, ERS, ESCMID, IDSA) included specialists medicine, clinical microbiology, laboratory patient advocacy. Systematic reviews were conducted around each 22 PICO (Population, Intervention, Comparator, Outcome) questions recommendations formulated, written, graded using GRADE (Grading Recommendations Assessment, Development, Evaluation) approach. Thirty-one evidence-based about treatment are provided. is intended for use healthcare professionals who care patients with disease, including diseases.

Language: Английский

Citations

566

Point-of-care diagnostics for infectious diseases: From methods to devices DOI Open Access
Chao Wang, Mei Liu, Zhifei Wang

et al.

Nano Today, Journal Year: 2021, Volume and Issue: 37, P. 101092 - 101092

Published: Feb. 7, 2021

Language: Английский

Citations

432

Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis DOI Open Access
Susan E. Dorman, Payam Nahid, Ekaterina V. Kurbatova

et al.

New England Journal of Medicine, Journal Year: 2021, Volume and Issue: 384(18), P. 1705 - 1718

Published: May 5, 2021

Rifapentine-based regimens have potent antimycobacterial activity that may allow for a shorter course in patients with drug-susceptible pulmonary tuberculosis.

Language: Английский

Citations

401

Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies DOI Creative Commons
Narges Alipanah, Leah G. Jarlsberg, Cecily Miller

et al.

PLoS Medicine, Journal Year: 2018, Volume and Issue: 15(7), P. e1002595 - e1002595

Published: July 3, 2018

Background Incomplete adherence to tuberculosis (TB) treatment increases the risk of delayed culture conversion with continued transmission in community, as well failure, relapse, and development or amplification drug resistance. We conducted a systematic review meta-analysis interventions, including directly observed therapy (DOT), determine which approaches lead improved TB outcomes. Methods findings systematically reviewed Medline references published articles for relevant studies multidrug both drug-susceptible drug-resistant through February 3, 2018. included randomized controlled trials (RCTs) prospective retrospective cohort (CSs) an internal external control group that evaluated any intervention their impact on Our search identified 7,729 articles, 129 met inclusion criteria quantitative analysis. Seven categories were identified, DOT offered by different providers at various locations, reminders tracers, incentives enablers, patient education, digital technologies (short message services [SMSs] via mobile phones video-observed [VOT]), staff combinations these interventions. When compared alone, self-administered (SAT) was associated lower rates success (CS: ratio [RR] 0.81, 95% CI 0.73–0.89; RCT: RR 0.94, 0.89–0.98), 0.83, 0.75–0.93), sputum smear (RCT: 0.92, 0.87–0.98) higher resistance 4.19, 2.34–7.49). provided healthcare providers, family members rate 0.86, 0.79–0.94). delivery community versus clinic 1.08, 1.01–1.15) end two months 1.05, 1.02–1.08) failure 0.56, 0.33–0.95) loss follow-up 0.63, 0.40–0.98). Medication monitors VOT comparable DOT. SMS led completion one RCT cure when used combination medication monitors. outcomes provider psychological employed. are limited heterogeneity lack standardized research methodology Conclusion use such education counseling, health technologies. Trained provides patient-centered options enhance improve unsupervised, SAT alone.

Language: Английский

Citations

385

Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline DOI
Payam Nahid, Sundari Mase, Giovanni Battista Migliori

et al.

American Journal of Respiratory and Critical Care Medicine, Journal Year: 2019, Volume and Issue: 200(10), P. e93 - e142

Published: Nov. 15, 2019

Section:ChooseTop of pageAbstract <

Language: Английский

Citations

371

Extrapulmonary tuberculosis DOI
Surendra K. Sharma,

Alladi Mohan,

Mikashmi Kohli

et al.

Expert Review of Respiratory Medicine, Journal Year: 2021, Volume and Issue: 15(7), P. 931 - 948

Published: May 9, 2021

Introduction: Tuberculosis (TB) is a major cause of morbidity and mortality globally. Extrapulmonary TB (EPTB) constitutes about 15%-20% all patients, but accounts for 50% among HIV-coinfected. Confirmation microbial diagnosis EPTB usually challenging.Areas covered: Availability newer imaging modalities like 18FDG-PET-CT PET-MRI has facilitated precise anatomical localization the lesions mapping extent EPTB. The use image- endoscopy-guided invasive diagnostic methods made procurement tissue/body fluids testing possible. With advent universal drug-susceptibility testing, rapid drug-resistance now possible in Drug-susceptible responds well to first-line anti-TB treatment; meningitis, bone joint lymph node requires longer durations treatment.Expert opinion: Adjunctive corticosteroids initial period recommended central nervous system pericardial TB. Surgical intervention helpful obtain tissue samples diagnosis. surgical treatment along with medical useful treating complications hydrocephalus, Pott's spine. Follow-up patients crucial as prolonged, recognition development immune reconstitution inflammatory syndrome (IRIS), monitoring adverse events, serious events drug-induced hepatotoxicity, organ-related complications, adherence.

Language: Английский

Citations

363

Tuberculosis: progress and advances in development of new drugs, treatment regimens, and host-directed therapies DOI
Simon Tiberi, Nelita du Plessis, Gerhard Walzl

et al.

The Lancet Infectious Diseases, Journal Year: 2018, Volume and Issue: 18(7), P. e183 - e198

Published: March 23, 2018

Language: Английский

Citations

330