Microorganisms,
Journal Year:
2024,
Volume and Issue:
12(11), P. 2121 - 2121
Published: Oct. 23, 2024
Antimicrobial
resistance
(AMR)
has
long
been
framed
as
an
epidemiological
and
public
health
concern.
Its
impacts
on
the
environment
are
unclear.
Yet,
basis
for
AMR
is
altered
cell
physiology.
Just
this
affects
how
microbes
interact
with
antimicrobials,
it
can
also
affect
they
their
own
species,
other
non-living
environment.
Moreover,
if
globally
notorious
causing
landscape-level
environmental
issues,
then
these
effects
could
alter
biodiversity
ecosystem
function
a
grand
scale.
To
investigate
possibilities,
we
compiled
peer-reviewed
literature
from
past
20
years
regarding
in
toxic
freshwater
cyanobacterial
harmful
algal
blooms
(HABs).
We
examined
evidence
of
affecting
HAB
frequency,
severity,
or
persistence.
Although
no
study
within
our
scope
was
explicitly
designed
to
address
question,
multiple
studies
reported
AMR-associated
changes
HAB-forming
cyanobacteria
(and
co-occurring
microbes)
that
pertained
directly
timing,
toxicity,
phase,
well
dynamics
HAB-afflicted
aquatic
food
webs.
These
findings
highlight
potential
have
far-reaching
(including
loss
function)
bring
into
focus
importance
confronting
complex
interrelated
issues
such
HABs
concert,
interdisciplinary
tools
perspectives.
Microbial Genomics,
Journal Year:
2023,
Volume and Issue:
9(8)
Published: Aug. 7, 2023
Iron
is
essential
for
growth
in
most
bacteria
due
to
its
redox
activity
and
role
metabolic
reactions;
it
a
cofactor
many
bacterial
enzymes.
The
bacterium
Acinetobacter
baumannii
multidrug-resistant
nosocomial
pathogen.
A.
responds
low
iron
availability
imposed
by
the
host
through
exploitation
of
multiple
iron-acquisition
strategies,
which
are
likely
deliver
cell
under
variety
environmental
conditions,
including
human
animal
infection.
To
date,
six
different
gene
clusters
active
uptake
have
been
described
,
encoding
protein
systems
involved
(i)
ferrous
(
feo
);
(ii)
haem
hemT
hemO
(iii)
synthesis
transport
baumannoferrin(s)
bfn
),
acinetobactin
bas
/
bau
)
fimsbactin(s)
fbs
siderophores.
Here
we
describe
structure,
distribution
phylogeny
iron-uptake
among
>1000
genotypically
diverse
isolates,
showing
that
very
prevalent
across
dataset,
whereas
additional
haem-uptake
system
only
present
portion
dataset
cluster
rare.
Since
expression
can
be
linked
virulence,
presence
may
contributed
success
some
clones.
npj Antimicrobials and Resistance,
Journal Year:
2025,
Volume and Issue:
3(1)
Published: April 23, 2025
Abstract
The
vaginal
resistome
can
be
considered
a
collection
of
the
resistant
determinants
in
microbiome.
Here
we
review
including
microbes
and
genes
harbored
common
gynecological
infections,
that
participate
horizontal
gene
transfer,
host
factors
contribute
to
resistome,
therapies.
Finally,
provide
perspective
on
technologies
leveraged
study
remaining
challenges.
mSphere,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 26, 2024
ABSTRACT
The
bacterial
genus
Acinetobacter
includes
species
found
in
environmental
habitats
like
soil
and
water,
as
well
taxa
adapted
to
be
host-associated
or
pathogenic.
High
genetic
diversity
may
allow
for
this
habitat
flexibility,
but
the
specific
genes
underlying
switches
between
are
poorly
understood.
One
lineage
of
has
undergone
a
substantial
change
by
evolving
from
presumed
soil-dwelling
ancestral
state
thrive
floral
nectar.
Here,
we
compared
genomes
floral-dwelling
pollinator-associated
,
including
newly
described
species,
with
relatives
other
environments
determine
genomic
changes
associated
ecological
shift.
Following
one
evolutionary
origin
nectar
adaptation,
nectar-dwelling
have
reduction
genome
size
experienced
dynamic
gene
gains
losses
they
diversified.
Gene
content
suggest
shift
metabolism
monosaccharides
rather
than
diverse
carbohydrates,
scavenging
nitrogen
sources,
which
predict
beneficial
environments.
appear
result
duplication
events,
divergence,
horizontal
transfer.
Most
notably,
acquired
ability
degrade
pectin
plant
pathogens,
duplicated
under
selection
within
clade.
We
hypothesize
that
was
key
trait
adaptation
nectar,
it
could
improve
access
nutrients
nutritionally
unbalanced
These
results
identify
traits
coinciding
dramatic
switch
IMPORTANCE
Many
bacteria,
commonly
evolve
exploit
new
habitats.
However,
underlie
often
unknown.
Floral
is
home
specialized
microbes
can
grow
habitat.
Several
evolved
become
common
abundant
investigate
adaptations
required
successfully
colonize
novel
performed
comparative
genomics
analyses
environments,
water.
find
although
loss
coincided
living
bacteria
been
particularly
important
change.
gained
degrading
pectin,
polysaccharide,
their
environment.
findings
shed
light
on
how
novelty
evolves
bacteria.
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Nov. 2, 2023
Abstract
The
bacterial
genus
Acinetobacter
includes
species
found
in
environmental
habitats
like
soil
and
water,
as
well
adapted
to
be
host-associated
or
pathogenic.
High
genetic
diversity
may
allow
for
this
habitat
flexibility,
but
the
specific
genes
underlying
switches
between
are
poorly
understood.
One
lineage
of
has
undergone
a
substantial
change
by
evolving
from
presumed
soil-dwelling
ancestral
state
thrive
floral
nectar.
Here
we
compared
genomes
floral-dwelling
pollinator-associated
,
including
newly
described
species,
with
relatives
other
environments
determine
genomic
changes
associated
ecological
shift.
Following
one
evolutionary
origin
nectar
adaptation,
nectar-dwelling
have
reduction
genome
size
experienced
dynamic
gene
gains
losses
they
diversified.
We
content
carbohydrate
metabolism
nitrogen
metabolism,
which
predict
beneficial
environments.
Gene
follow
pattern
consistent
streamlining,
whereas
appear
result
both
divergence
horizontal
transfer.
Most
notably,
acquired
ability
degrade
pectin
plant
pathogens
duplicated
under
selection
within
clade.
hypothesize
that
was
key
trait
adaptation
nectar,
it
could
improve
access
nutrients
nutritionally
unbalanced
These
results
identify
traits
coinciding
dramatic
switch
