Zebrafish as a model system for studying reproductive diseases DOI Creative Commons

Wenwen Zha,

Weitao Hu,

Chenkai Ge

et al.

Frontiers in Cell and Developmental Biology, Journal Year: 2024, Volume and Issue: 12

Published: Dec. 23, 2024

Reproductive system diseases have become a major health challenge facing humans, so extensive investigations are needed to understand their complex pathogenesis and summarize effective treatments. In the study of reproductive diseases, mice most commonly used animal model. However, cost time required establish mouse models high. The existing zebrafish model can solve this problem well. Zebrafish is an with great application prospects has lots advantages, including high degree genetic conservation short cycle, transparent embryos, rapid growth, providing unique opportunities for high-throughput drug screening identification potential Researchers successfully chemical induction, physical damage, gene editing technology, etc., induce damage in biological processes related its diseases. Therefore, review, main advantages summarized, pathological mechanisms as disease clarified, new perspectives valuable insights provided treatment human literature data cited review all from PubMed, covering important research results on past 10 years.

Language: Английский

The Research Advances in Distant Hybridization and Gynogenesis in Fish DOI Creative Commons
Qizhi Liu, Wang Shi, Chenchen Tang

et al.

Reviews in Aquaculture, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 10, 2024

ABSTRACT Distant hybridization and gynogenesis are two prevalent breeding techniques for fishes. Drawing from the research achievements of our team existing literature, we summarize reproductive traits genetic features fishes derived distant hybridizations gynogenesis, deduce fundamental mechanisms these methods compare them, discerning their common different characteristics. Both can alter genotypes phenotypes, thus establishing them as significant methods. Additionally, principles basic biological characteristics in fish have been inferred. We propose concepts macro‐hybrid micro‐hybrid based on extensive experimental findings gynogenesis. The term “macro‐hybrid” refers to offspring that possess distinct subgenomes, each inherited one parental species, such allodiploid allotetraploid lineages. concept “micro‐hybrid” offspring, including autodiploid autotetraploid lineages, well those resulting artificial whose genome almost originates solely maternal parent but which certain DNA fragments paternal insert. vital genetics, breeding, evolution. highlight prospective paths application

Language: Английский

Citations

7
Triploidy induction through cntd1 knockout in red crucian carp (Carassius auratus red var.) DOI
Huilin Li,

Yu Zhang,

Lina Zhang

et al.

Aquaculture, Journal Year: 2025, Volume and Issue: unknown, P. 742347 - 742347

Published: Feb. 1, 2025

Language: Английский

Citations

0
A new method for creating androgenetic diploid fish from tetraploid carp sperm and their genetic composition analysis DOI
Haoran Gu, Qilong Liu, Yi Fan

et al.

Aquaculture, Journal Year: 2024, Volume and Issue: 590, P. 741077 - 741077

Published: May 12, 2024

Language: Английский

Citations

1
Zebrafish as a model system for studying reproductive diseases DOI Creative Commons

Wenwen Zha,

Weitao Hu,

Chenkai Ge

et al.

Frontiers in Cell and Developmental Biology, Journal Year: 2024, Volume and Issue: 12

Published: Dec. 23, 2024

Reproductive system diseases have become a major health challenge facing humans, so extensive investigations are needed to understand their complex pathogenesis and summarize effective treatments. In the study of reproductive diseases, mice most commonly used animal model. However, cost time required establish mouse models high. The existing zebrafish model can solve this problem well. Zebrafish is an with great application prospects has lots advantages, including high degree genetic conservation short cycle, transparent embryos, rapid growth, providing unique opportunities for high-throughput drug screening identification potential Researchers successfully chemical induction, physical damage, gene editing technology, etc., induce damage in biological processes related its diseases. Therefore, review, main advantages summarized, pathological mechanisms as disease clarified, new perspectives valuable insights provided treatment human literature data cited review all from PubMed, covering important research results on past 10 years.

Language: Английский

Citations

1