Journal of Advanced Research,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Plants
produce
abundant
natural
products,
among
which
are
species-specific
and
diversified
secondary
metabolites
that
essential
for
growth
development,
as
well
adaptation
to
adversity
ecology.
Moreover,
these
extensively
utilized
in
pharmaceuticals,
fragrances,
industrial
materials,
more.
WRKY
transcription
factors
(TFs),
a
family
of
TFs
unique
plants,
have
significant
functions
many
plant
life
activities.
Especially
recent
years,
their
role
the
field
metabolite
biosynthesis
regulation
has
received
much
attention.
However,
very
little
comprehensive
summarization
been
done
review
research
progress.
The
purpose
this
work
is
not
only
provide
valuable
insights
into
over
metabolic
pathways
through
compiling
involved
processes,
but
also
offer
directions
by
summarizing
regulatory
modes
metabolites,
thereby
increasing
yield
products
future.
Secondary
can
be
categorized
three
major
classes-terpenoids,
phenolic
compounds,
nitrogen-containing
compounds-based
on
structural
characteristics
biosynthetic
pathways,
further
subdivided
numerous
subclasses.
We
detail
progressregardingthe
roles
metabolitebiosynthesis
summarize
more
than
40
related
species.
Additionally,
we
presented
concepts
action
including
direct
regulation,
indirect
co-regulation,
self-regulation.
It
helpful
others
investigate
molecular
mechanisms
TF-mediated
regulation.
Furthermore,
regarding
future
prospects,
believe
area
lays
foundation
important
plant-derived
breeding,
generating
economic
social
benefits.
The Plant Journal,
Journal Year:
2024,
Volume and Issue:
119(5), P. 2168 - 2180
Published: July 11, 2024
SUMMARY
Mass
spectrometry
imaging
(MSI)
has
become
increasingly
popular
in
plant
science
due
to
its
ability
characterize
complex
chemical,
spatial,
and
temporal
aspects
of
metabolism.
Over
the
past
decade,
as
emerging
unique
features
various
MSI
techniques
have
continued
support
new
discoveries
studies
metabolism
closely
associated
with
function
physiology,
spatial
metabolomics
based
on
positioned
it
at
forefront
metabolic
studies,
providing
opportunity
for
far
higher
resolution
than
was
previously
available.
Despite
these
efforts,
profound
challenges
levels
resolution,
sensitivity,
quantitative
ability,
chemical
confidence,
isomer
discrimination,
multi‐omics
integration,
undoubtedly
remain.
In
this
Perspective,
we
provide
a
contemporary
overview
emergent
widely
used
sciences,
particular
emphasis
recent
advances
methodological
breakthroughs.
Having
established
detailed
context
MSI,
outline
both
golden
opportunities
key
currently
facing
metabolomics,
presenting
our
vision
how
enormous
potential
technologies
will
contribute
progress
coming
years.
Proceedings of the National Academy of Sciences,
Journal Year:
2025,
Volume and Issue:
122(12)
Published: March 19, 2025
Plants
produce
diverse
specialized
metabolites
with
important
ecological
functions.
It
has
recently
become
apparent
that
the
genes
for
many
of
these
pathways
are
not
dispersed
in
plant
genomes,
but
rather
arranged
like
beads
on
a
string
biosynthetic
gene
clusters
(BGCs).
Pathways
encoded
by
BGCs
as
rule
dedicated
linear
do
form
parts
wider
metabolic
networks.
In
contrast,
biosynthesis
widely
distributed
more
ancestral
such
carotenoids
and
anthocyanins
clustered.
Little
is
known
about
how
evolved
clustered
interact
general
metabolism.
We
characterized
12-gene
BGC
antimicrobial
defense
compound
avenacin
A-1,
triterpene
glycoside
produced
oats.
Avenacin
A-1
acylated
fluorophore
N
-methyl
anthranilate
confers
bright
blue
fluorescence
oat
root
tips
under
ultraviolet
light.
Here,
we
exploit
suite
>100
avenacin-deficient
mutants
identified
screening
reduced
to
identify
required
function
this
paradigm
BGC.
Using
combination
mutant
chemotyping,
biochemical
molecular
analysis,
genome
resequencing,
two
nonclustered
(
Sad4
Pal2
)
encoding
enzymes
synthesize
donors
glycosylation
acylation
(recruited
from
phenylpropanoid
tryptophan
pathways).
Our
finding
Cluster
Auxiliary
Enzymes
(CAEs)
provides
insights
into
interplay
between
metabolism
newly
lineage-specific
Philosophical Transactions of the Royal Society B Biological Sciences,
Journal Year:
2024,
Volume and Issue:
379(1914)
Published: Sept. 29, 2024
Immense
chemical
diversity
is
one
of
the
hallmark
features
plants.
This
chemo-diversity
mainly
underpinned
by
a
highly
complex
and
biodiverse
biochemical
machinery.
Plant
metabolic
enzymes
originated
were
inherited
from
their
eukaryotic
prokaryotic
ancestors
further
diversified
unprecedentedly
high
rates
gene
duplication
functionalization
experienced
in
land
Unlike
microbes,
which
display
frequent
horizontal
transfer
events
multiple
inputs
energy
organic
carbon,
plants
predominantly
rely
on
carbon
generated
CO
2
have
relatively
few
transfers
during
recent
evolutionary
history.
As
such,
plant
networks
evolved
stepwise
manner
using
existing
as
starting
point
under
various
constraints.
That
said,
until
recently,
evolution
only
handful
traits
had
been
extensively
investigated
metabolism
has
received
fraction
attention
of,
development,
for
example.
Advances
metabolomics
next-generation
sequencing
have,
however,
recently
led
to
deeper
understanding
how
wide
range
primary
specialized
(secondary)
pathways
both
consequence
natural
selection
domestication
crop
improvement
processes.
article
part
theme
issue
‘The
metabolism’.
Journal of Experimental Botany,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 19, 2024
Abstract
Plants
are
unique
organisms
that
have
developed
ingenious
strategies
to
cope
with
environmental
challenges,
such
as
herbivorous
insects.
One
of
these
is
the
synthesis
a
vast
array
chemical
compounds,
known
specialized
metabolites,
serve
many
ecological
functions.
Among
most
fascinating
and
diverse
groups
metabolites
alkaloids,
which
characterized
by
presence
nitrogen
atom
within
heterocyclic
ring.
While
some
medicinal
recreational
applications,
others
highly
unpalatable
and/or
toxic.
The
effects
alkaloids
on
both
humans
insects
can
be
very
diverse,
affecting
their
physiology
behavior.
Insects
feed
alkaloid-containing
plants
evolved
various
mechanisms
consequences
toxins.
These
include
sequestration,
where
store
in
tissues
or
organs,
enzymatic
detoxification
through
enzymes
cytochrome
P450
monooxygenases
glutathione
S-transferases,
behavioral
adaptations
selective
feeding.
In
this
review,
we
explore
relationships
between
plant
evolutionary
enable
exploit
alkaloid-rich
food
sources
niches
minimizing
harmful
natural
compounds.
We
aim
provide
comprehensive
updated
overview
complex
interaction.
