Enhancing Maize Yield and Quality with Metal-Based Nanoparticles without Translocation Risks: A Brief Field Study DOI Creative Commons
Dávid Ernst, Marek Kolenčík, Martin Šebesta

et al.

Plants, Journal Year: 2024, Volume and Issue: 13(14), P. 1936 - 1936

Published: July 14, 2024

Our previous studies have shown physiological and yield intensification of selected crops with the application nanoparticles (NPs). However, impact on quantitative, qualitative, parameters maize (Zea mays L.) in field conditions remains highly debated. This study aimed to evaluate effects zinc oxide (ZnO-NPs), gold NPs anchored meso-biosilica (Au-NP-bioSi), titanium dioxide (TiO2-NPs) as biological stimulants under during vegetation season 2021 Central European region. The assessed number plants, yield, components, nutritional quality, including mineral nutrients, starch, crude protein levels. potential translocation these chemically–physically stable NPs, which could pose a hazard, was also investigated. results indicate that Au-NP-bioSi ZnO-NPs-treatments were most beneficial for components at statistically significant level. Mineral nutrient outcomes varied, NP-free variant performing best phosphorus-levels, while ZnO-NPs optimal protein. Starch content comparable across TiO2-NPs, Au-NP-bioSi, control variants. Importantly, we observed no hazardous or negative impacts grain quality. supports hypothesis can serve an effective tool precise sustainable agriculture.

Language: Английский

Comprehensive Review of Mesoporous Silica Nanoparticles: Drug Loading, Release, and Applications as Hemostatic Agents DOI
Talib M. Albayati, Saja Mohsen Alardhi,

Ali H. Khalbas

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(23)

Published: June 18, 2024

Abstract Recently, mesoporous silica nanoparticles (MSNs) have emerged as promising candidates in the field of hemorrhage control owing to their extended pore size, high surface area, and excellent biocompatibility. These characteristics directly influence toxicity cells, loading therapeutic agents, release active ions during hemostasis process. Therefore, understanding fundamentals tuning these is important design types carriers. While several literature reviews explored role MSNs control, comprehensive studies focusing on general specific applications remain scarce. This review concentrates principles synthesizing silica, MSNs, techniques for drugs methods onto site injury, kinetics models, biocompatibility, toxicity, unique properties MSNs. Furthermore, article examines mechanism action nanomaterial hemostatic agents.

Language: Английский

Citations

32
Treatment of phenolic-wastewater by hybrid technologies: A review DOI
Fatima Mumtaz, Baosong Li,

Maryam R. Al Shehhi

et al.

Journal of Water Process Engineering, Journal Year: 2023, Volume and Issue: 57, P. 104695 - 104695

Published: Dec. 29, 2023

Language: Английский

Citations

22
A review of the extraction methods and advanced applications of lignin-silica hybrids derived from natural sources DOI

Co D. Pham,

Minh D. T. Dang,

Tuyen B. Ly

et al.

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 230, P. 123175 - 123175

Published: Jan. 6, 2023

Language: Английский

Citations

21
Additive Manufacturing of Bioactive Glass and Its Polymer Composites as Bone Tissue Engineering Scaffolds: A Review DOI Creative Commons
Lizhe He, Jun Yin, Xiang Gao

et al.

Bioengineering, Journal Year: 2023, Volume and Issue: 10(6), P. 672 - 672

Published: June 1, 2023

Bioactive glass (BG) and its polymer composites have demonstrated great potential as scaffolds for bone defect healing. Nonetheless, processing these materials into complex geometry to achieve either anatomy-fitting designs or the desired degradation behavior remains challenging. Additive manufacturing (AM) enables fabrication of BG BG/polymer objects with well-defined shapes intricate porous structures. This work reviewed recent advancements made in AM composite intended tissue engineering. A literature search was performed using Scopus database include publications relevant this topic. The properties based on different inorganic formers, well composites, are first introduced. Melt extrusion, direct ink writing, powder bed fusion, vat photopolymerization technologies that compatible were terms their advances. value lies ability produce patient-specific on-demand spatial distribution biomaterials, both contributing effective healing, by vivo studies. Based relationships among structure, physiochemical properties, biological function, AM-fabricated valuable achieving safer more efficient healing future.

Language: Английский

Citations

14
A review on toxicity mechanism and risk factors of nanoparticles in respiratory tract DOI
Vidyasri Khadanga, Purna Chandra Mishra

Toxicology, Journal Year: 2024, Volume and Issue: 504, P. 153781 - 153781

Published: March 15, 2024

Language: Английский

Citations

6
Ordered Mesoporous Silica Delivering siRNA as Cancer Nanotherapeutics: A Comprehensive Review DOI
A. Gupta,

Avishek Mallick Choudhury,

Jairam Meena

et al.

ACS Biomaterials Science & Engineering, Journal Year: 2024, Volume and Issue: 10(5), P. 2636 - 2658

Published: April 12, 2024

Nanosized mesoporous silica has emerged as a promising flexible platform delivering siRNA for cancer treatment. This ordered nanosized provides attractive features of well-defined and tunable porosity, structure, high payload, multiple functionalizations targeted delivery increasing biocompatibility over other polymeric nanocarriers. Moreover, it also overcomes the lacunae associated with traditional administration drugs. Chemically modified porous matrix efficiently entraps molecules prevents their enzymatic degradation premature release. Review discusses synthesis using sol-gel approach advantages different mesostructure. Herein, factors affecting at nanometer scale, shape, porosity nanoparticle surface modification are highlighted to attain desired nanostructured carriers. Additional emphasis is given chemically siRNA, where was chemical moieties such amine (3-aminoropyl) triethoxysilane, polyethylenimine, chitosan, poly(ethylene glycol), cyclodextrin polymer therapeutic loading, improved dispersibility biocompatibility. Upon systemic administration, encounters blood cells, immune organs mainly reticuloendothelial system (RES). Thereby, biodistribution based nanocarriers deliberated design principles smart efficacious silica-siRNA carriers clinical trial status. further reports future scopes challenges developing nanomaterial vehicle demanding FDA approval.

Language: Английский

Citations

5
Quantitative determination of the intracellular uptake of silica nanoparticles using asymmetric flow field flow fractionation coupled with ICP mass spectrometry and their cytotoxicity in HepG2 cells DOI
Yuki Tanaka, Yasumitsu Ogra

Archives of Toxicology, Journal Year: 2024, Volume and Issue: 98(3), P. 769 - 777

Published: Jan. 14, 2024

Language: Английский

Citations

4
Amorphous silica nanoparticles caused lung injury through the induction of epithelial apoptosis via ROS/Ca 2+ /DRP1-mediated mitochondrial fission signaling DOI
Yan Li,

Yawen Zhu,

Bosen Zhao

et al.

Nanotoxicology, Journal Year: 2022, Volume and Issue: 16(6-8), P. 713 - 732

Published: Sept. 14, 2022

The adverse effects of amorphous silica nanoparticles (SiNPs) exposure on the respiratory system were increasingly recognized, however, its potential pathogenesis still remains not fully elucidated. So, this study aimed to explore pulmonary injury, and investigate related mechanisms. Histological investigations illustrated SiNPs triggered lung mainly manifested as alveolar structure destruction, collagen deposition, mitochondrial ultrastructural injury. In particular, greatly enhanced ROS TUNEL positive rate in lungs, both which positively correlated with impairments. Further, underlying mechanisms investigated cultured human bronchial epithelial cells (16HBE). Consistent vivo findings, caused impairments structure, well activation generation oxidative Upon stimuli, respiration was inhibited, while Ca2+ overload cytosol mitochondria owing ER calcium release noticed, resulting mitochondrial-dependent apoptosis. More importantly, dynamics imbalanced toward a fission type, evidenced by upregulated DRP1 phosphorylation at Ser616 (DRP1s616), downregulated DRP1s637, also MFN1, MFN2. Mechanistic revealed that ROS/Ca2+ signaling promoted DRP1-mediated SiNPs, forming vicious cycle, ultimately contributing apoptosis 16HBE. summary, our results disclosed injury through induction via ROS/Ca2+/DRP1-mediated axis.

Language: Английский

Citations

18
Nanosilica from Averrhoa bilimbi juice pre-treated rice husk: Preparation and characterization DOI
Midhun Dominic,

K.V. Neenu,

P.M. Sabura Begum

et al.

Journal of Cleaner Production, Journal Year: 2023, Volume and Issue: 413, P. 137476 - 137476

Published: May 11, 2023

Language: Английский

Citations

10
Revolutionizing Nanovaccines: A New Era of Immunization DOI Creative Commons
Mohammed A. Saleh,

Ahmed El-Moghazy,

Adel Helmy Elgohary

et al.

Vaccines, Journal Year: 2025, Volume and Issue: 13(2), P. 126 - 126

Published: Jan. 27, 2025

Infectious diseases continue to pose a significant global health threat. To combat these challenges, innovative vaccine technologies are urgently needed. Nanoparticles (NPs) have unique properties and emerged as promising platform for developing next-generation vaccines. revolutionizing the field of development, offering new era immunization. They allow creation more effective, stable, easily deliverable Various types NPs, including lipid, polymeric, metal, virus-like particles, can be employed encapsulate deliver components, such mRNA or protein antigens. These NPs protect antigens from degradation, target them specific immune cells, enhance antigen presentation, leading robust durable responses. Additionally, simultaneously multiple antigens, adjuvants, in single formulation, simplifying production administration. Nanovaccines offer approach food- water-borne bacterial diseases, surpassing traditional formulations. Further research is needed address burden infections. This review highlights potential revolutionize platforms. We explore their mechanisms action, current applications, emerging trends. The discusses limitations nanovaccines, solutions role artificial intelligence effective accessible nanovaccines infectious diseases.

Language: Английский

Citations

0