North American Proceedings in Gynecology & Obstetrics,
Journal Year:
2024,
Volume and Issue:
3(3)
Published: July 27, 2024
Background
Gestational
Diabetes
(GDM)
raises
the
risk
of
adverse
perinatal
outcomes
and
long-term
type
2
diabetes.
There
is
currently
a
lack
comprehensive
GDM
prediction
models
based
on
more
than
simple
clinical
features.
Objective
The
objective
this
study
was
to
collect
set
clinical,
sociodemographic,
biobehavioral,
genomic
features
in
prospective
high-risk
cohort
for
GDM,
discover
novel
predictive
therapeutic
targets
during
early
pregnancy.
Study
design
Hoosier
Moms
Cohort
observational
pregnant
individuals,
with
singleton
gestation
<20
weeks.
protocol
included
visits
pregnancy
one
at
delivery.
Psychosocial,
dietary,
social,
demographic
characteristics
were
collected
addition
maternal
newborn
samples.
Developing
primary
outcome.
Univariate
associations
continuous
variables
analyzed
using
either
two-sample
t-test
or
Wilcoxon
Rank
Sum
test,
categorical
chi-square
Fishers
exact
test.
Multiple
logistic
regression
performed
independent
GDM.
Results
A
total
411
participants
recruited,
complete
data
available
391.
Patients
average
30
years
age,
had
mean
body
mass
index
(BMI)
28,
17%
Hispanic
ethnicity.
Additionally,
54%
reported
family
history
diabetes,
4%
reporting
personal
prior
39
(10.0%)
developed
Compared
those
that
did
not,
who
significantly
higher
baseline
BMI
(31.6
vs
27.2,
p=0.003),
HbA1c
(5.24
5.07,
p<0.001),
triglycerides
(156.8
134.2,
p=0.022),
random
blood
glucose
(85.90
79.96,
p=0.025)
initial
visit.
Those
likely
have
gestational
diabetes
(28.21%
1.96%,
current
chronic
hypertension
(12.82%
1.9%,
p=0.003).
they
scored
validated
insomnia
questionnaire
(9.62
7.80,
p=0.028).
significant
association
found
between
3
previously
genetic
markers
(p<0.01).
Individuals
high
polygenic
scores
not
diagnosis.
Through
stepwise
regression,
diagnosis
hypertension,
insomnia,
independently
associated
(odds
ratio,
95%
confidence
intervals:
14.98,
4.49-50.02;
10.94,
2.32-51.69;
1.11,
1.01-1.22;
1.09,
1.03-1.16,
respectively).
Conclusion
identified
previous
diagnosis,
elevated
BMI,
increased
odds
developing
diverse
participants.
These
factors
will
be
integrated
into
machine
learning
model
multi-omics
develop
predictor
American Journal of Obstetrics and Gynecology,
Journal Year:
2023,
Volume and Issue:
229(3), P. 193 - 213
Published: April 27, 2023
Preeclampsia
is
a
multisystemic
disorder
of
pregnancy
that
affects
250,000
pregnant
individuals
in
the
United
States
and
approximately
10
million
worldwide
per
annum.
associated
with
substantial
immediate
morbidity
mortality
but
also
long-term
for
both
mother
offspring.
It
now
clearly
established
low
dose
aspirin
given
daily,
beginning
early
modestly
reduces
occurrence
preeclampsia.
Low-dose
seems
safe,
because
there
paucity
information
about
effects
on
infant,
it
not
recommended
all
individuals.
Thus,
several
expert
groups
have
identified
clinical
factors
indicate
sufficient
risk
to
recommend
low-dose
preventive
therapy.
These
may
be
complemented
by
biochemical
and/or
biophysical
tests
either
increased
probability
preeclampsia
factors,
or
more
importantly,
identify
likelihood
those
without
other
evident
risk.
In
addition,
opportunity
exists
provide
this
population
additional
care
prevent
mitigate
short-
Patient
provider
education,
surveillance,
behavioral
modification,
approaches
improve
outcomes
these
can
chance
healthy
outcome.
We
assembled
group
diverse,
relevant
expertise
(clinicians,
investigators,
advocates,
public
private
stakeholders)
develop
plan
which
providers
at
work
together
reduce
morbidities.
The
moderate
high
developing
preeclampsia,
receive
therapy,
as
laboratory
findings.
recommendations
are
presented
using
GRADE
methodology
quality
evidence
upon
each
based.
printable
appendices
concise
summaries
plan's
patients
healthcare
provided.
believe
shared
approach
will
facilitate
prevention
its
attendant
development
disorder.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(2), P. e24085 - e24085
Published: Jan. 1, 2024
BackgroundAccording
to
statistics,
about
one-fifth
of
the
world's
elderly
people
suffer
from
sleep
disorders,
and
problem
disorders
in
is
extremely
serious,
this
one
important
causes
chronic
diseases
such
as
hypertension,
hyperlipidemia,
diabetes
mellitus,
coronary
heart
disease
elderly.
The
positive
effect
Tai
Chi
exercise
therapy
on
problems
has
been
confirmed,
but
at
present,
specific
duration
improvement
with
moderate
severe
varies.ObjectiveMETA
analysis
was
used
investigate
find
that
long-term
best
improving
patients
disorders.
Methods:
META
performed
using
Revman
5.3
after
searching
Web
science,
Pubmed,
Scopus,
Cochroae
Library,
OVID,
CBM,
CNKI,
VIP,
other
databases,
then
filtering
extracting.ResultsA
total
seven
papers
were
included.
Meta-analysis
showed
tai
chi
more
effective
compared
control
group,
difference
significant.
This
demonstrated
by
a
decrease
global
Pittsburgh
Sleep
Quality
Index
(PSQI)
score
[SMD
=
−0.66,
95
%
CI
(−0.91,
−0.41),
P
<
0.00001],
well
its
subdomains
subjective
quality
−0.79,
(−1.06,
−0.52),
latency
−0.80,
(−1.21,
−0.40),
−0.38,
(−0.72,
−0.04),
0.03],
habitual
efficiency
−0.58,
(−0.84,
−0.31),
0.0001],
disturbance
−0.51,
(−0.78,
−0.25),
0.00001]
daytime
dysfunction
−0.33,
(−0.59,
−0.07),
0.01].
Improvement
also
observed
Epworth
Sleepiness
Scale
(ESS)
Insomnia
Severity
(ISI).
results
optimal
frequency
for
moderately
long-term.ConclusionThis
study
systematically
assessed
efficacy
moderate-to-severe
Through
meta-analysis
relevant
randomized
controlled
trials
(RCTs),
it
aims
determine
effectiveness
compare
effects
those
traditional
treatments;
analyze
safety
patient
population
assess
feasibility
non-pharmacological
therapy;
fill
research
gaps
provide
comprehensive
systematic
evidence
support.
provides
practical
approach
reducing
risk
medication
side
older
adults
offers
potentially
treatment
option,
especially
who
are
unable
or
unwilling
use
medication.
may
not
only
improve
sleep,
coordination,
muscle
strength,
balance,
reduce
stress
anxiety
adults.
It
helps
socialize
enhances
their
social
connections
emotional
suggests
community
centers
activity
can
organize
classes
promote
participation
adults,
be
scientific
rehabilitation
tool
clinical
treatment,
incorporating
practice
into
daily
life,
fixed
time
every
day
week,
which
improves
overall
life.
Applied Sciences,
Journal Year:
2023,
Volume and Issue:
13(2), P. 753 - 753
Published: Jan. 5, 2023
Obstructive
sleep
apnea
(OSA)
is
a
common
disorder
that
has
high
prevalence
in
the
obese
population.
Studies
have
established
relationship
between
OSA
and
multitude
of
adverse
health
outcomes
including
cardiovascular
diseases
metabolic
diseases,
indicating
nature
as
with
comorbidity
mortality.
Thus,
growing
public
concern
face
rising
obesity
trends
globally.
This
study
conducted
systematic
analysis
scientific
literature
on
from
1977
to
2022
order
gain
better
understanding
major
research
areas
concerning
connections
these
areas.
Findings
indicate
there
are
clusters
investigating
which
conditions
commonly
associated
significant
disease
burden.
The
findings
this
scientometric
also
emerging
into
more
specific
populations
such
children
pregnant
women.
BMC Pregnancy and Childbirth,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: March 6, 2025
Sleep
disorders
are
among
the
most
common
major
problems
during
pregnancy.
Most
studies
on
sleep
of
pregnant
women
closely
related
to
adverse
birth
outcomes.
In
this
study,
our
aim
was
develop
and
validate
a
predictive
model
for
risk
in
women.
A
total
2,467
healthy
were
enrolled
randomly
partitioned
into
training
set
validation
at
ratio
7:3.
During
variable
selection
stage,
Pearson's
chi-square
test
employed
identify
variables
with
p-value
below
0.05,
which
then
designated
as
candidate
subsequent
logistic
regression
analysis.
Concurrently,
LASSO
technique
utilized
sift
through
isolate
valuable
variables.
Ultimately,
we
developed
binary
Logistic
models
predicated
(Model
1)
2).
The
performance
nomograms
evaluated
using
Bootstrap
resampling
procedure,
sensitivity
specificity
receiver-operating
characteristic
(ROC),
area
under
ROC
curve
(AUC),
decision
analysis
(DCA).
439
(25.4%)
208
(28.1%)
exhibited
disorder,
respectively.
prediction
shared
6
factors
(age,
anxiety,
depression,
family
functions,
degree
pregnancy
reaction,
pre-pregnancy
physical
condition).
Model
1,
69.4%,
59.6%.
When
weeks,
residence,
only
child
included
2,
82.4%
54.8%.
set,
areas
1
2
0.678
(0.635,
0.720),
0.719
(0.678,
0.761),
showed
that
calibration
is
approximately
distributed
along
reference
line.
Decision
analyses
demonstrated
favorable
net
benefit
within
range
threshold
probability
nomograms.
superior
performance,
can
serve
convenient
reliable
tool
predicting
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(9), P. 1434 - 1434
Published: April 24, 2025
Objective:
The
aim
of
this
study
was
to
assess
the
association
between
Dietary
Inflammatory
Index
(DII)
and
depression
in
mid-pregnancy
mediating
effect
sleep
quality
according
Edinburgh
Postnatal
Depression
Scale
(EPDS).
Methods:
This
a
cross-sectional
conducted
2017–2019
at
maternal
child
health
centre
Hunan
Province.
After
applying
inclusion
exclusion
criteria,
749
pregnant
women
were
finally
included
study.
A
multifactorial
logistic
regression
model
used
estimate
odds
ratio
(OR)
95%
confidence
interval
(95%
CI)
DII
on
depression.
Restricted
cubic
spline
plot
analyse
nonlinearity
Mediation
effects
models
role
quality.
Results:
average
age
29.42
±
4.22
years.
mean
0.21
1.48
overall
presenting
rate
9.35%.
In
final
adjusted
for
covariates
such
as
age,
race,
body
mass
index
(BMI),
occupation,
literacy,
monthly
income,
risk
Q3
3.51
times
higher
than
Q4
[OR
=
3.51,
CI
(1.45
8.53)].
high
factor
(p
<
0.05).
analyses
showed
that
could
not
be
considered
nonlinear.
Sleep
may
play
(25.26%
total
effect).
Conclusions:
is
can
influence
only
directly
but
also
indirectly
through
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: May 4, 2025
Good
sleep
quality
is
crucial
for
health
and
body
equilibrium,
particularly
during
pregnancy,
where
changes
in
are
influenced
by
mechanical
hormonal
factors.
Poor
can
hinder
daily
activities
lead
to
adverse
pregnancy
outcomes.
Data
on
scarce
low
middle-income
countries
such
as
Ethiopia.
Hence,
this
study
aimed
determine
the
magnitude
of
its
associated
factors
among
pregnant
mothers
Bahir
Dar
City,
northwest
A
facility-based
cross-sectional
was
conducted
with
367
randomly
selected
women.
All
women
who
attended
public
facilities
City
from
November
1st
December
30,
2022
were
included
except
critically
ill
aged
less
than
18
years.
The
data
collected
through
face-to-face
interviews.
Sleep
assessed
using
Pittsburgh
Quality
Index
(PSQI).
Stata
v14
used
analysis.
binary
logistic
regression
model
identify
poor
quality.
Statistical
significance
set
at
p
<
0.05.
prevalence
55.04%.
In
multivariable
analysis,
older
maternal
age
(AOR
=
3.62),
third
trimester
2.83),
multigravidas
2.55),
hemoglobin
1.92),
coffee
consumption
2.19)
More
half
had
Women
≥
30
years,
3rd
trimester,
multigravidas,
anemic
women,
concerned
should
pay
attention
improving
Hgb
level
iron/folate
supplementation
reduce
intake
improve
pregnancy.
JAMA Network Open,
Journal Year:
2024,
Volume and Issue:
7(8), P. e2427557 - e2427557
Published: Aug. 13, 2024
Importance
Pregnancy
may
contribute
to
the
development
or
exacerbation
of
obstructive
sleep
apnea
(OSA)
and
increase
risk
gestational
complications.
Continuous
positive
airway
pressure
(CPAP)
is
first-line
criterion
standard
treatment
for
OSA
regarded
as
most
feasible
choice
during
pregnancy.
However,
association
between
CPAP
therapy
in
pregnant
women
with
reduced
complications
remains
inconclusive.
Objective
To
investigate
reduction
adverse
hypertensive
outcomes
gestation.
Data
Sources
Keyword
searches
PubMed,
Embase,
Cochrane
Database
Systematic
Reviews
Clinical
Trials
were
conducted
from
inception
November
5,
2023.
Study
Selection
Original
studies
reporting
effect
use
on
lowering
hypertension
preeclampsia
risks
selected.
Extraction
Synthesis
The
Preferred
Reporting
Items
Meta-Analyses
(PRISMA)
guideline
was
followed
reviews.
independently
extracted
by
2
authors.
Random-effects
model
meta-analyses
performed
ratios
(RRs)
reported.
Subgroup
analysis,
meta-regression
based
age
body
mass
index
(BMI;
calculated
weight
kilograms
divided
height
meters
squared),
publication
bias
assessment
also
conducted.
Main
Outcome
Measures
primary
outcome
RR
receiving
those
who
did
not
receive
treatment.
Results
Six
original
809
participants
(mean
age,
31.4
years;
mean
BMI,
34.0)
identified
systematically
reviewed
meta-analysis.
pooled
results
showed
significant
differences
intervention
(CPAP
use)
control
(non-CPAP
groups
reducing
(RR,
0.65;
95%
CI,
0.47-0.89;
P
=
.008)
0.70;
0.50-0.98;
.04).
Meta-regression
revealed
that
patients’
(coefficient,
−0.0190;
.83)
BMI
−0.0042;
.87)
correlated
preeclampsia.
Conclusions
Relevance
These
findings
suggest
implementing
reduce