The impact of acute and prior SARS-CoV-2 infection on maternal and neonatal outcomes in pregnant women: a single-center retrospective cohort study DOI Creative Commons
Yujie Tang, Liang Chen, Tao Han

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Dec. 6, 2023

Abstract Background Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection during pregnancy have an adverse impact on perinatal outcomes, including cesarean section, preterm birth, fetal distress. However, it’s uncertain whether these consequences are caused by acute viral or post-acute of infection. Methods We conducted a single-center retrospective cohort study among pregnant women with singleton who delivered between 1 December 2022 and February 2023 (n = 2472). The clinical data for mothers neonates came from medical records internal healthcare system. Follow-up time spanned admission to discharge. investigated the prior SARS-CoV-2 maternal neonatal outcome. Multivariable logistic models were used assess risk outcome in Results Compared non-infected women, infected had significant higher rates intrahepatic cholestasis (ICP) (26 [4.4%] vs. 8 [1.0%]; aOR, 4.9 [95% CI, 2.2–11.0]; P < 0 .001), birth (༜37 wk) (53women [9.0%] 45 [5.7%]; 1.7 1.1–2.7]; 0.05), distress(106 [18.1%] 82 [10.4%]; aOR,1.9 1.4–2.6]; .01), first-cesarean section (216 [36.9%] 239women [30.3%]; 1.4[95% 1.1–1.8]; 0.01) unit (69 [12%] 64 [8.3%]; 1.6 1.1–2.3]; associated increased ICP (40 [3.7%] 3.9 1.8–8.5]; .001). Conclusions Pregnant was ICP, distress, admission. Prior ICP. These findings emphasize need optimization strategies prevention especially at delivery.

Language: Английский

Incidence of new-onset in-hospital and persistent diabetes in COVID-19 patients: comparison with influenza DOI Creative Commons
Justin Y. Lu,

Jack Wilson,

Wei Hou

et al.

EBioMedicine, Journal Year: 2023, Volume and Issue: 90, P. 104487 - 104487

Published: Feb. 28, 2023

Language: Английский

Citations

45
Maternal and neonatal outcomes following SARS-CoV-2 infection DOI
Lillian B. Boettcher, Torri D. Metz

Seminars in Fetal and Neonatal Medicine, Journal Year: 2023, Volume and Issue: 28(1), P. 101428 - 101428

Published: Feb. 1, 2023

Language: Английский

Citations

19
The Importance of Vaccination, Variants and Time Point of SARS-CoV-2 Infection in Pregnancy for Stillbirth and Preterm Birth Risk: An Analysis of the CRONOS Register Study DOI Open Access
Antonella Iannaccone, Alexandra Gellhaus,

Beatrix Reisch

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(6), P. 1522 - 1522

Published: March 7, 2024

Background: The risk of preterm birth (PTB) and stillbirth increases after a SARS-CoV-2 infection during gestation. We aimed to estimate the depending on gestational age at (early <28 + 0 late ≥28 weeks gestation, WoG), virus variants, severity infection, vaccination. Methods: PTB was divided into early (<32 0) (32 0–36 6 WoG). prospective register COVID-19 Related Obstetrics Neonatal Outcome Study (CRONOS) included 8032 pregnant women with confirmed from 3 April 2020 31 December 2022, in Germany Austria. Results: Stillbirth births rates were higher Alpha (1.56% 3.13%) Delta 3.44%) waves than Omicron wave (0.53% 1.39%). Early increased for (aRR 5.76, 95% CI 3.07–10.83) before 32 (aRR, 6.07, 3.65–10.09). Hospital admission risks further, especially case ICU admission. Vaccination against significantly reduced 0.32, 0.16–0.83). Conclusions: This multicentric study shows an pregnancy therefore importance obstetrical surveillance thereafter. offers effective protection.

Language: Английский

Citations

6
The impact of acute and prior SARS-CoV-2 infection on maternal and neonatal outcomes in pregnant women: a single-center retrospective cohort study DOI Creative Commons
Yujie Tang, Liang Chen, Tao Han

et al.

BMC Pregnancy and Childbirth, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 18, 2025

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection in pregnant women have an adverse impact on perinatal outcomes, including cesarean section, preterm birth, fetal distress. However, it's uncertain whether these consequences are caused by previous SARS-COV-2 during pregnancy or acute at the time of delivery. We conducted a single-center retrospective cohort study among with singleton who delivered between 1 December 2022 and February 2023 (n = 2472). Pregnancies were divided into three groups: non-infected group, SARS-CoV-2 prior group based PCR antigen test. The clinical data for mothers neonates came from medical records internal healthcare system. Follow-up spanned admission to discharge. investigated maternal neonatal outcome. Multivariable logistic models used assess risk outcome infection. Compared women, infected had significant higher rates intrahepatic cholestasis (ICP) (26 [4.4%] vs. 8 [1.0%]; aOR, 4.9 [95% CI, 2.2–11.0]; P < 0.001), birth (<37 wk) (53women [9.0%] 45 [5.7%]; 1.7 1.1–2.7]; 0.05), distress(106 [18.1%] 82 [10.4%]; aOR,1.9 1.4–2.6]; 0.01), primary delivery (216 [36.9%] 239women [30.3%]; 1.4[95% 1.1–1.8]; 0.01) unit (69 [12%] 64 [8.3%]; 1.6 1.1–2.3]; associated increased ICP (40 [3.7%] 3.9 1.8–8.5]; <0.001). Pregnant ICP, distress, admission. Prior was ICP. These findings emphasize need optimization strategies prevention especially

Language: Английский

Citations

0
Long‐term clinical outcomes and healthcare utilization of sickle cell disease patients with COVID‐19: A 2.5‐year follow‐up study DOI
Avery Feit, Moshe Gordon, Tharun T. Alamuri

et al.

European Journal Of Haematology, Journal Year: 2023, Volume and Issue: 111(4), P. 636 - 643

Published: July 26, 2023

Abstract Objectives This study investigated whether patients with sickle cell disease (SCD) had elevated risk of worse long‐term clinical outcomes and healthcare utilization 2.5 years post‐SARS‐CoV‐2 infection. Methods consisted 178 SCD who tested positive for COVID‐19 between February 1, 2020 January 30, 2022 in a major academic health system New York City. The control cohort two‐to‐one matches 356 without test. last follow‐up was July 18, 2022. primary outcome mortality. Secondary were annualized emergency department visits due to pain, pain hospital admission, length stay acute chest syndrome, episodic transfusion, exchange transfusion. Results There no significant difference mortality ( p > .05). differences secondary pre‐ postpandemic also these care not significantly associated hospitalization status Conclusions SARS‐CoV‐2 infection incurred additional compared matched controls infected by SARS‐CoV‐2.

Language: Английский

Citations

8
Implication of viruses in the etiology of preeclampsia DOI
Kenichiro Motomura, Hideaki Morita, Katsuhiko Naruse

et al.

American Journal of Reproductive Immunology, Journal Year: 2024, Volume and Issue: 91(4)

Published: April 1, 2024

Abstract Preeclampsia is one of the most common disorders that poses threat to both mothers and neonates a major contributor perinatal morbidity mortality worldwide. Viral infection during pregnancy not typically considered cause preeclampsia; however, syndromic nature preeclampsia etiology immunomodulatory effects viral infections suggest microbes could trigger subset preeclampsia. Notably, SARS‐CoV‐2 associated with an increased risk Herein, we review potential role in this great obstetrical syndrome. According vitro vivo experimental studies, can by introducing poor placentation, syncytiotrophoblast stress, and/or maternal systemic inflammation, which are all known play critical development Moreover, clinical investigations have suggested link between several viruses onset via multiple pathways. However, results research always consistent. Therefore, future studies should investigate causal elucidate mechanism behind relationship itself.

Language: Английский

Citations

2
Neonatal outcomes of maternal prenatal coronavirus infection DOI
İstemi Han Çelik, Atakan Tanaçan, Fuat Emre Canpolat

et al.

Pediatric Research, Journal Year: 2023, Volume and Issue: 95(2), P. 445 - 455

Published: Dec. 6, 2023

Language: Английский

Citations

6
Management of neonates with maternal prenatal coronavirus infection and influencing factors DOI
İstemi Han Çelik, Aslınur Özkaya Parlakay, Fuat Emre Canpolat

et al.

Pediatric Research, Journal Year: 2023, Volume and Issue: 95(2), P. 436 - 444

Published: Oct. 19, 2023

Language: Английский

Citations

6
SARS-CoV-2 perinatal transmission and neonatal outcomes across four different waves of COVID-19 pandemic: A nationwide prospective cohort study from the Italian Society of Neonatology DOI Creative Commons
Lorenza Pugni, Beatrice Letizia Crippa, Francesco Raimondi

et al.

International Journal of Infectious Diseases, Journal Year: 2023, Volume and Issue: 140, P. 17 - 24

Published: Dec. 28, 2023

To describe how SARS-CoV-2 infection at the time of delivery affected maternal and neonatal outcomes across four major waves COVID-19 pandemic in Italy.

Language: Английский

Citations

4
A Survey on the Knowledge, Attitudes, Behaviors and Influencing Factors of Caregivers for Newborns With COVID-19 in Chongqing, China DOI Open Access

Xiaojun Tao,

Yanhan Chen,

Ye Xu

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 27, 2024

This study aimed to investigate the healthcare knowledge, attitudes, and behaviors of primary caregivers newborns with coronavirus disease 2019 (COVID-19) during pandemic in Chongqing, China, analyze influencing factors.

Language: Английский

Citations

0