Current concepts and recent trends in endothelial keratoplasty
World Journal of Transplantation,
Journal Year:
2025,
Volume and Issue:
15(2)
Published: Feb. 21, 2025
Endothelial
keratoplasty
(EK)
is
defined
as
an
umbrella
term
comprising
methods
for
selective
surgical
replacement
of
corneal
endothelium
and
adjacent
tissue,
which
retains
healthy
portions
a
patient's
cornea
while
replacing
diseased
innermost
layer(s)
with
donor
to
achieve
dehydration
transparency
before
the
onset
irreversible
stromal
edema
permanent
loss
clarity.
Recently,
pathophysiology
decompensation
increasingly
being
researched
upon.
Consequent
improvement
in
pharmacotherapy
progressively
leading
reduction
indications
EK.
In
addition,
EK
techniques
have
progressed
towards
using
thinner
optimizing
visual
outcomes.
Improvements
enabled
better
tissue
formulation,
usage,
attachment,
modifications
enhanced
utilization
difficult
clinical
scenarios
lowering
failure
rejection.
However,
challenges
are
encountered
various
complex
including
eyes
prior
intraocular
surgery,
anterior
chamber
anatomy,
glaucoma,
ocular
surface
disease
etc.
These
complexities
demand
tailored
strategies,
graft
handling,
instrumentation,
postoperative
management
ensure
success.
Attention
these
details
addressing
patient-specific
factors
can
help
improve
outcomes
cases.
The
choice
procedure
depends
on
multiple
factors,
surgeon's
experience,
specific
scenario.
This
review
article
encompasses
recent
developments
this
field
presenting
comprehensive
picture
our
modern
understanding
indications,
contraindications,
techniques,
situations,
community
aspects
future
directions
pertaining
Language: Английский
Corneal Artificial Endothelial Layer (EndoArt): Literature Review and Our Experience
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(21), P. 6520 - 6520
Published: Oct. 30, 2024
:
The
objective
of
this
study
was
to
examine
the
morphological
corneal
changes
and
outcomes
following
implantation
an
artificial
endothelial
layer
(EndoArt)
in
patients
with
chronic
oedema.
Language: Английский
Descemet Membrane Endothelial Keratoplasty Graft Preparation Using the Liquid Bubble Technique with Subtrabecular Hydrodissection: A Retrospective Real-Life Study
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(20), P. 6048 - 6048
Published: Oct. 10, 2024
Background:
Techniques
for
the
preparation
of
grafts
Descemet
membrane
endothelial
keratoplasty
(DMEK)
can
be
classified
into
those
that
involve
manual
dissection
(DM)
and
use
an
injection
a
liquid
or
gas
to
achieve
separation
DM
from
posterior
corneal
stroma.
The
purpose
this
study
was
evaluate
efficiency
bubble
technique.
Methods:
success
rate
technique
calculated
retrospectively
using
operating
reports.
Video
files
each
graft
were
retrieved
time,
number
injections,
injections
sites
required
hydrodissection
measured.
cases
in
which
necessary
recorded.
Information
on
donor
age
preservation
time
eye
bank
file.
Results:
In
58
cases,
98.3%.
28
procedures
where
video
available,
median
4.4
min.
2,
with
3.5.
Manual
as
rescue
performed
25%
one
case
resulting
tears.
mean
diameter
7.6
mm.
66
years,
storage
22
days.
Conclusions:
fast
valuable
choice
DMEK
preparation,
especially
centers
tissue
is
prepared
theater.
Language: Английский