Atrial Fibrillation and Cancer—Epidemiology, Mechanisms, and Management DOI Open Access
Nathaniel E. Davis, Narut Prasitlumkum, Nicholas Y. Tan

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(24), P. 7753 - 7753

Published: Dec. 19, 2024

Atrial fibrillation (AF) and cancer are increasingly recognized as interrelated conditions, with patients showing elevated incidences of AF, there is evidence that AF may sometimes precede diagnoses. This comprehensive review investigates the epidemiology, pathophysiology, management challenges associated in patients. Epidemiologically, several cancers more closely related to increased rates including lung, colorectal, gastrointestinal, hematologic malignancies. Mechanistically, both share pathophysiological pathways centered on inflammation, oxidative stress, common cardiovascular risk factors, such hypertension, obesity, diabetes. The inflammatory microenvironment tumors, marked by cytokines growth promotes atrial remodeling susceptibility. Elevated reactive oxygen species (ROS) levels, driven metabolic demands cancer, further contribute fibrosis structural changes. Moreover, many anticancer treatments exacerbate risk. Management presents unique requires a multidisciplinary approach. Rate rhythm control strategies complicated potential drug–drug interactions limited data surrounding early implementation Interventional approaches catheter ablation, though effective maintaining sinus rhythm, carry significant perioperative malignancy. Stroke prevention anticoagulants essential but cautious administration avoid heightened bleeding risks, particularly undergoing chemotherapy. Further, applicability standard stratification tools like CHA2DS2-VASc this population complicate decisions regarding anticoagulation. highlights bidirectional relationship between difficulties management, critical need for research field.

Language: Английский

Letter to the Editor “Machine learning to develop a novel model for predicting new-onset postoperative atrial fibrillation after coronary artery bypass grafting” DOI Creative Commons
Zhan Peng,

Xiaozheng Zhou,

Xiubin Yang

et al.

International Journal of Surgery, Journal Year: 2024, Volume and Issue: unknown

Published: April 19, 2024

Department of Cardiovascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Institute Heart, Lung and Vessel Disease, 100029, China Zhan Peng Xiaozheng Zhou contributed equally to this work. Published online ■ *Corresponding author. Address: 2# Road, Cao Yang District, Beijing, China, 100029. E-mail address: [email protected] (X. Yang). district, (K. Hua). This is an open access article distributed under the terms Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others remix, tweak, build upon work non-commercially, as long author credited new creations are licensed identical terms. http://creativecommons.org/licenses/by-nc-sa/4.0/

Language: Английский

Citations

0
Examining the relationship between preoperative nutritional and symptom assessment and postoperative atrial fibrillation in esophageal squamous cell carcinoma patients: a retrospective cohort study DOI Creative Commons
Yunyun Chen, Yan Ma,

Haiyan Wu

et al.

BMC Surgery, Journal Year: 2024, Volume and Issue: 24(1)

Published: Oct. 9, 2024

The study aimed to examine the relationship between preoperative nutritional status, symptom burden, and occurrence of postoperative atrial fibrillation in Esophageal Squamous Cell Carcinoma patients.

Language: Английский

Citations

0
Atrial Fibrillation and Cancer—Epidemiology, Mechanisms, and Management DOI Open Access
Nathaniel E. Davis, Narut Prasitlumkum, Nicholas Y. Tan

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(24), P. 7753 - 7753

Published: Dec. 19, 2024

Atrial fibrillation (AF) and cancer are increasingly recognized as interrelated conditions, with patients showing elevated incidences of AF, there is evidence that AF may sometimes precede diagnoses. This comprehensive review investigates the epidemiology, pathophysiology, management challenges associated in patients. Epidemiologically, several cancers more closely related to increased rates including lung, colorectal, gastrointestinal, hematologic malignancies. Mechanistically, both share pathophysiological pathways centered on inflammation, oxidative stress, common cardiovascular risk factors, such hypertension, obesity, diabetes. The inflammatory microenvironment tumors, marked by cytokines growth promotes atrial remodeling susceptibility. Elevated reactive oxygen species (ROS) levels, driven metabolic demands cancer, further contribute fibrosis structural changes. Moreover, many anticancer treatments exacerbate risk. Management presents unique requires a multidisciplinary approach. Rate rhythm control strategies complicated potential drug–drug interactions limited data surrounding early implementation Interventional approaches catheter ablation, though effective maintaining sinus rhythm, carry significant perioperative malignancy. Stroke prevention anticoagulants essential but cautious administration avoid heightened bleeding risks, particularly undergoing chemotherapy. Further, applicability standard stratification tools like CHA2DS2-VASc this population complicate decisions regarding anticoagulation. highlights bidirectional relationship between difficulties management, critical need for research field.

Language: Английский

Citations

0