Association of depressive symptom trajectories with chronic kidney disease in middle-aged and older adults

Journal of Psychosomatic Research, Journal Year: 2025, Volume and Issue: 189, P. 112036 - 112036

Published: Jan. 4, 2025

Language: Английский

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Psychiatric disorders and following risk of chronic kidney disease: a prospective cohort study from UK Biobank

BMC Psychiatry, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 11, 2025

Psychiatric disorders have been reported to influence many health outcomes, but evidence about their impact on chronic kidney disease (CKD) has not fully explored, as well possible mechanisms implicated are still unclear. Four hundred forty-one thousand eight ninety-three participants from UK Biobank were included in this study. To assess the association between psychiatric mainly including depression, anxiety, stress-related disorders, substance misuse psychotic disorder, and CKD, a Cox regression model using age underlying time scale was employed. This approach considers progression of beginning end study elapsed time. Flexible nonparametric smoothing conducted illustrate temporal patterns. Subgroup analyses performed by stratification gender, genetic susceptibility at entry or exit cohort, follow-up duration, number baseline. Mediation analysis implemented evaluate roles body mass index (BMI), hypertension, diabetes. Compared with individuals without an increased risk CKD observed patients (hazard ratios (HR) = 1.52, 95% confidence intervals (CI): 1.40–1.65, p-value < 0.001). The hazard ratio among gradually increased, became significant after 10 years follow-ups. HR for followed up 10–12 1.60 (95% CI: 1.34–1.91, 0.001), 1.66 1.29–2.13, 0.001) 12–13 years. Five distinct found be significantly associated developing CKD. highest disorder (HR 1.95, 95%CI: 1.28–2.97, 0.002). When adjusting 1.86 (95%CI: 1.14–3.04, 0.013). Although these associations nominally significant, they did reach statistical significance applying Bonferroni multiple corrections, potentially due limited sample size. revealed that who under 60, morbidities having diagnosed over may high-risk populations. Hypertension, BMI diabetes mediated 49.13% 37.60%-67.08%), 12.11% 8.49%-17.24%) 3.78% 1.58%-6.52%) total effect, respectively. delayed onset elevated only more than Our highlights lifestyle interventions, routine monitoring function, early screening personalized management strategies potential approaches precise prevention

Language: Английский

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Number of chronic diseases and cognitive function among the elderly in China: a moderated mediation model

Frontiers in Psychology, Journal Year: 2025, Volume and Issue: 16

Published: March 3, 2025

Purpose Despite the wealth of data on role chronic disease comorbidity in shaping cognitive dysfunction older adults, a comprehensive view this dynamic interplay remains frontier. This study will reveal intricate interactions between number diseases and function elderly, based perspective patients with multiple diseases. Methods Our was from 2023 China Psychological Care for Elderly Action Survey, SPSS 26.0 (IBM Corp., Armonk, NY, United States) software package used mediation model analysis. The approach encompassed descriptive analysis variables, Spearman’s correlation analyses to explore associations moderated Results found that ( r = 0.183, p &lt; 0.001) positively correlated function. Anxiety depression partially mediated relationship β 0.227, 0.235, both 0.001). Age association 0.010, Conclusion provides establishes new adults. It suggests we should pay attention negative impact elderly improve their psychological coping ability, so as ensure stable development healthy aging.

Language: Английский

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Mapping the global research landscape on depression for patients with chronic kidney disease: a bibliometric and visualized analysis from 2006 to 2022

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: July 17, 2024

Chronic Kidney Disease (CKD), a complex and multifaceted health issue, significantly contributes to global mortality rates. Accompanying chronic conditions, depression notably exacerbates outcomes, increasing both risk the burden on affected individuals. This study employs bibliometric visual analytics evaluate evolution, current trends, future research directions in field of CKD depression.

Language: Английский

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Research Progress on Cognitive Frailty in Older Adults with Chronic Kidney Disease

Kidney & Blood Pressure Research, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 1

Published: April 26, 2024

<b><i>Background:</i></b> As the medical challenges posed by ageing population become increasingly severe, proportion of older people among patients with chronic kidney disease (CKD) is increasing every year. <b><i>Summary:</i></b> The prevalence frailty in CKD significantly higher than that general population, and are also a high-risk group for cognitive impairment. Cognitive frailty, as an important subtype syndrome characterised dysfunction caused physiological factors, excluding Alzheimer’s other types dementia. It coexistence physical Previous studies have mainly focused on impairment, there limited research particularly CKD. <b><i>Key Messages:</i></b> This article provides comprehensive review concept, epidemiology, screening methods, prevention, treatment measures possible pathogenesis

Language: Английский

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The Relationship between Plant-Based Diet Indices and Sleep Health in Older Adults: The Mediating Role of Depressive Symptoms and Anxiety

Nutrients, Journal Year: 2024, Volume and Issue: 16(19), P. 3386 - 3386

Published: Oct. 5, 2024

Background: The goal of our research was to determine the effects plant-based dietary patterns on sleep health among older adults and examine parallel mediated anxiety depression. Methods: This investigation utilized data obtained from 2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS) contained 6853 participants. Logistic regression restricted cubic splines (RCSs) model were employed how affect health. Additionally, Amos 26.0 used construct a structural equation Results: A higher diet index (PDI) connected odds better quality (OR = 1.209, 95% CI: 1.039–1.407) duration 1.241, 1.072–1.437). Conversely, an elevated unhealthy (uPDI) correlated with lower likelihood 0.678, 0.574–0.800) 0.762, 0.647–0.896). RCSs further identified significant dose–response relationship. Mediation analysis confirmed that depression partially mediate relationship between diets Conclusions: Our study exhibited correlations in elderly. Depression determined as mediators Controlling early affective disorder could help improve adults.

Language: Английский

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Relationship between sleep quality and fear of progression among partients with chronic kidney disease: A cross-sectional survey

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 28, 2024

Objectives The study aims to elucidate the direct correlation between sleep quality and fear of progression (FOP), two significant psychosocial issues that individuals with chronic kidney disease (CKD) encounter. Methods A cross-sectional was conducted among patients CKD who were recruited from Second Affiliated Hospital Anhui Medical University.Clinical demographic data collected using a general information questionnaire. Fear Progression Questionnaire-Short Form Pittsburgh Sleep Quality Index used measure level FOP evaluate over one month. investigated utilizing Pearson hierarchical regression analysis. Results This comprised 195 people in total, which 116 (59.5%) suffered poor quality.Sleep positively correlated, higher scores leading poorer quality. Gender, family financial burden, stage, total score could predict Collectively, these factors combined explained 24.7% variation quality, independently contributing 6.3% variance. Conclusions Patients often experience an issue healthcare professionals should take seriously. Interventions focused on reducing offer promising approach enhancing

Language: Английский

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Were there any missing mediators between visual impairment and anxiety symptoms? Results from Chinese Longitudinal Healthy Longevity Survey

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Oct. 16, 2024

Introduction Visual impairment, encompassing low visual acuity and field loss, significantly impacts the older adult population worldwide, leading to increased disability mortality risks. Recent studies suggest a strong association between impairment anxiety, particularly among adults. This study aims explore relationship anxiety symptoms in individuals China, investigate potential mediating factors. Methods Data for this were derived from 2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS), including 11,702 participants aged 65 older. was assessed through self-reported function, while measured using 7-item Generalized Anxiety Disorder scale (GAD-7). Additional assessments included sleep quality duration, exercise status, dietary diversity. Logistic regression models mediation analysis employed associations effects. Results The findings indicate that is associated with (OR = 1.51, 95% CI: 1.32–1.72, p &lt; 0.001). Mediation revealed quality, diversity score (DDS), plant-based DDS mediated anxiety. In contrast, exercise, animal-based did not show significant Conclusion crucial predictor of adult. Improving promoting diverse diet may mitigate population. Interventions targeting these areas could enhance mental health life impairment.

Language: Английский

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Healthy Lifestyle Behaviors Attenuate the Effect of Poor Sleep Patterns on Chronic Kidney Disease Risk: A Prospective Study from the UK Biobank

Nutrients, Journal Year: 2024, Volume and Issue: 16(23), P. 4238 - 4238

Published: Dec. 8, 2024

This study aimed to assess the impact of modifiable lifestyle behaviors on association between sleep patterns and chronic kidney disease (CKD) risk.

Language: Английский

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