Infant Formula Supplemented with Biotics: Current Knowledge and Future Perspectives

Nutrients, Journal Year: 2020, Volume and Issue: 12(7), P. 1952 - 1952

Published: June 30, 2020

Breastfeeding is natural and the optimal basis of infant nutrition development, with many benefits for maternal health. Human milk a dynamic fluid fulfilling an infant’s specific nutritional requirements guiding growth, developmental, physiological processes infant. considered unique in composition, it influenced by several factors, such as diet health, body geographic region. stands model formula providing solutions infants not able to receive enough mother’s milk. Infant formulas aim mimic composition functionality human ingredients reflecting those latest insights, oligosaccharides, bacteria, bacterial metabolites. The objective this narrative review discuss most recent developments special focus on oligosaccharides postbiotics.

Language: Английский

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Breast Milk: A Source of Functional Compounds with Potential Application in Nutrition and Therapy

Nutrients, Journal Year: 2021, Volume and Issue: 13(3), P. 1026 - 1026

Published: March 22, 2021

Breast milk is an unbeatable food that covers all the nutritional requirements of infant in its different stages growth up to six months after birth. In addition, breastfeeding benefits both maternal and child health. Increasing knowledge has been acquired regarding composition breast milk. Epidemiological studies epigenetics allow us understand possible lifelong effects breastfeeding. this review we have compiled some components with clear functional activity are present human processes through which they promote development maturation as well modulate immunity. Milk fat globule membrane, proteins, oligosaccharides, factors, exosomes, or microorganisms use formulas, any other products, supplements, nutraceuticals, even for new clinical therapies. The evaluation these compounds their commercial exploitation limited by difficulty isolating producing them on adequate scale. work focus produced using from species such bovine, transgenic cattle capable expressing microbial culture engineering.

Language: Английский

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Clinical implications of preterm infant gut microbiome development

Nature Microbiology, Journal Year: 2021, Volume and Issue: 7(1), P. 22 - 33

Published: Dec. 23, 2021

Language: Английский

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Probiotics for Preventing Necrotizing Enterocolitis in Preterm Infants: A Network Meta-Analysis

Nutrients, Journal Year: 2021, Volume and Issue: 13(1), P. 192 - 192

Published: Jan. 9, 2021

Background: Recent evidence supports a role of probiotics in preventing necrotizing enterocolitis (NEC) preterm infants. Methods: A systematic review and network meta-analysis randomized controlled trials (RCTs) on the NEC infants, focusing differential effect type feeding, was performed following Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) guidelines. random-effects model used; subgroup analysis exclusively human milk (HM)-fed infants vs. receiving formula (alone or with HM) performed. Results: Fifty-one were included (10,664 29 probiotic interventions); 31 studies (19 different regimens) suitable according to feeding. In overall analysis, Lactobacillus acidophilus LB revealed most promising reducing risk (odds ratio (OR), 0.03; 95% credible intervals (CrIs), 0.00–0.21). The showed that Bifidobacterium lactis Bb-12/B94 associated reduced stage ≥2 both feeding populations, discrepancy relative size favour HM-fed (OR 0.04; CrIs <0.01–0.49 OR 0.32; 0.10–0.36). Conclusions: B. could reduce type. Of note, strains are evaluated few relatively small outcome data not available all RCTs. Further needed confirm present findings.

Language: Английский

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Early Enteral Feeding in Preterm Infants: A Narrative Review of the Nutritional, Metabolic, and Developmental Benefits

Nutrients, Journal Year: 2021, Volume and Issue: 13(7), P. 2289 - 2289

Published: July 1, 2021

Enteral feeding is the preferred method of nutrient provision for preterm infants. Though parenteral nutrition remains an alternative to provide critical after delivery, literature suggests that enteral still confers significant nutritional and non-nutritional benefits. Therefore, purpose this narrative review summarize health clinical benefits early within first month life in Likewise, also proposes methods improve delivery care, including a proposal decision-making initiation advancement feeding. An extensive assessed studies infants with subsequent outcomes. The findings support impact infant by enhancing micronutrient promoting intestinal development maturation, stimulating microbiome development, reducing inflammation, brain growth neurodevelopment. Clinicians must consider these short- long-term implications when caring

Language: Английский

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A systematic review of the factors influencing microbial colonization of the preterm infant gut

Gut Microbes, Journal Year: 2021, Volume and Issue: 13(1)

Published: Jan. 1, 2021

Prematurity coupled with the necessary clinical management of preterm (PT) infants introduces multiple factors that can interfere microbial colonization. This study aimed to review perinatal, physiological, pharmacological, dietary, and environmental associated gut microbiota PT infants. A total 587 articles were retrieved from a search databases. Sixty studies included in after removing duplicates did not meet inclusion criteria. Review this literature revealed evidence converged on effect postnatal age, mode delivery, use antibiotics, consumption human milk composition Less was found for associations race, sex, different fortifiers, macronutrients, other medications. Future rich metadata are needed further explore impact exposome development high-risk population.

Language: Английский

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Probiotics in Pediatrics. A Review and Practical Guide

Nutrients, Journal Year: 2021, Volume and Issue: 13(7), P. 2176 - 2176

Published: June 24, 2021

The potential benefit of the administration probiotics in children has been studied many settings globally. Probiotics products contain viable micro-organisms that confer a health on host. Beneficial effects selected probiotic strains for management or prevention pediatric conditions have demonstrated. purpose this paper is to provide an overview current available evidence efficacy specific guide pediatricians decision-making therapeutic prophylactic use children. Evidence support certain often available. In addition, associated with low risk adverse events and generally well tolerated. best documented treatment infectious gastroenteritis, antibiotic-associated, Clostridioides difficile-associated nosocomial diarrhea. Unfortunately, due study heterogeneity some cases high bias published studies, broad consensus lacking strains, doses regimens indications. thus limits systematic probiotics. most recent meta-analyses reviews highlight need more well-designed, properly powered, strain-specific dedicated-dose response studies.

Language: Английский

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Why Are Bifidobacteria Important for Infants?

Microorganisms, Journal Year: 2022, Volume and Issue: 10(2), P. 278 - 278

Published: Jan. 25, 2022

The presence of

Language: Английский

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Exploring the Potential of Human Milk and Formula Milk on Infants’ Gut and Health

Nutrients, Journal Year: 2022, Volume and Issue: 14(17), P. 3554 - 3554

Published: Aug. 29, 2022

Early-life gut microbiota plays a role in determining the health and risk of developing diseases later life. Various perinatal factors have been shown to contribute development establishment infant microbiota. One important influencing microbial colonization composition is mode feeding. While formula milk has designed resemble human as much possible, microbiome infants who receive differs from that are fed milk. A diverse population microbes seed microbiome. Human contains nutritional components promote growth bioactive components, such oligosaccharides, lactoferrin, immunoglobulins, which immunological development. In an attempt encourage formation healthy comparable breastfed infant, manufacturers often supplement with prebiotics or probiotics, known bifidogenic effect can modulate immune system. This review aims elucidate roles on infants' health.

Language: Английский

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Probiotic sepsis in preterm neonates—a systematic review

European Journal of Pediatrics, Journal Year: 2022, Volume and Issue: 181(6), P. 2249 - 2262

Published: March 29, 2022

Language: Английский

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