Emerging models to study competitive interactions within bacterial communities
Trends in Microbiology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Within
both
abiotic
and
host
environments,
bacteria
typically
exist
as
diverse,
multispecies
communities
have
crucial
roles
in
human
health,
agriculture,
industry.
In
these
communities,
compete
for
resources,
competitive
interactions
can
shape
the
overall
population
structure
community
function.
Studying
bacterial
dynamics
requires
experimental
model
systems
that
capture
different
interaction
networks
between
their
surroundings.
We
examine
recent
literature
advancing
such
systems,
including
(i)
silico
models
establishing
theoretical
basis
how
cell-to-cell
influence
level
dynamics,
(ii)
vitro
characterizing
specific
interbacterial
interactions,
(iii)
organ-on-a-chip
revealing
physiologically
relevant
parameters,
spatial
mechanical
forces,
encounter
within
a
host,
(iv)
vivo
plant
animal
connecting
responses
to
interactions.
Each
of
has
greatly
contributed
our
understanding
be
used
synergistically
understand
competition
influences
architecture.
Language: Английский
Influence of organophosphonates as alternative P-sources on bacterial transformation of glyphosate
Environmental Pollution,
Journal Year:
2025,
Volume and Issue:
unknown, P. 125872 - 125872
Published: Feb. 1, 2025
Language: Английский
Estimates of microbial community stability using relative invader growth rates are robust across levels of invader species richness
ISME Communications,
Journal Year:
2025,
Volume and Issue:
5(1)
Published: Jan. 1, 2025
A
key
feature
of
natural
communities
is
that
the
species
within
them
stably
coexist.
common
metric
used
to
test
community
stability
ability
each
invade
from
rare.
potential
issue
with
this
measurement
single
are
invaded
rare,
while
in
communities,
multiple
would
likely
decline
simultaneously
following
perturbations.
This
especially
microbes
which
can
be
rapidly
disturbed
by
environmental
stressors.
If
coexistence
dependent
on
indirect
interactions
among
members,
declining
may
result
instability.
As
such,
invading
a
into
overestimate
when
decline.
Here,
we
compare
estimates
five
microbial
experimental
results
invaded.
Our
showed
invasions
were
qualitatively
predictive
whole
simultaneously.
However,
quantitative
values
relative
invader
growth
rate
less
comparable,
being
non-significantly
different
most
comparisons
three
out
species.
was
emphasized
lack
correlation
between
exact
rates
under
or
multi-species
invasion.
work
provides
support
for
robustness
using
invasion
infer
qualitative
stability.
Language: Английский
Coexistence Theory for Microbial Ecology, and Vice Versa
Environmental Microbiology,
Journal Year:
2025,
Volume and Issue:
27(3)
Published: March 1, 2025
ABSTRACT
Classical
models
from
theoretical
ecology
are
seeing
increasing
uptake
in
microbial
ecology,
but
there
remains
rich
potential
for
closer
cross‐pollination.
Here
we
explore
opportunities
stronger
integration
of
ecological
theory
into
research
(and
vice
versa)
through
the
lens
so‐called
“modern”
coexistence
theory.
Coexistence
can
be
used
to
disentangle
contributions
different
mechanisms
(e.g.,
resource
partitioning,
environmental
variability)
make
species
coexistence.
We
begin
with
a
short
primer
on
fundamental
concepts
theory,
an
emphasis
relevance
communities.
next
present
systematic
review,
which
highlights
paucity
empirical
applications
systems.
In
light
this
gap,
then
identify
and
discuss
ways
which:
(i)
help
answer
applied
questions
particularly
spatio‐temporally
heterogeneous
environments,
(ii)
experimental
systems
leveraged
validate
advance
Finally,
address
several
unique
often
surmountable
challenges
posed
by
systems,
as
well
some
conceptual
limitations.
Nevertheless,
thoughtful
presents
wealth
advancement
both
ecology.
Language: Английский
Bacteria-phage (co)evolution is constrained in a synthetic community across multiple bacteria-phage pairs
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 17, 2024
Abstract
Bacteriophages
can
be
important
drivers
of
bacterial
densities,
and
therefore
microbial
community
composition
function.
These
ecological
interactions
are
likely
to
greatly
affected
by
evolutionary
dynamics,
because
bacteria
rapidly
evolve
resistance
phage
while
reciprocally
increase
infectivity.
Most
studies
date
have
explored
eco-evolutionary
dynamics
using
isolated
pairs
bacteria-phage
but
in
nature,
multiple
phages
coexist
(co)evolve
simultaneously.
How
coevolution
plays
out
this
context
is
poorly
understood.
Here,
we
examine
how
three
coexisting
soil
(
Ochrobactrum
sp.,
Pseudomonas
Variovorax
sp.)
interact
with
species-specific
bacteriophages
over
eight
weeks
experimental
evolution,
both
as
host-parasite
isolation
a
mixed
community.
Across
all
species
evolution
was
inhibited
polyculture,
the
most
pronounced
effect
on
.
Between
there
were
also
substantial
differences
host
including
whether
coevolved.
contrasts
emphasise
difficulty
generalising
from
monoculture
between
wider
systems.
Future
should
consider
simultaneously
better
understand
coevolutionary
happen
natural
communities.
Importance
This
project
unique
examining
among
their
phages,
rather
than
focus
single
focal
–
makes
our
work
more
applicable
contexts
still
working
controlled
synthetic
While
it
commonly
assumed
that
will
coevolve
phage,
may
uncommon
complex
communities
due
reduced
contact
rates
and/or
mutation
rates.
Furthermore,
contrast
population
ability
highlights
need
for
studied.
Over-reliance
model
systems
known
means
lack
an
understanding
interact,
what
extent
results
generalised
beyond
these
pairs.
Language: Английский
Bacteriophage resistance increases bacterial productivity by shifting population growth dynamics in the soil bacteriumVariovoraxsp
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 7, 2024
Abstract
Lytic
bacteriophages
(‘phages’)
can
limit
bacterial
densities,
either
directly
through
lysis
or
indirectly
costs
to
resistance.
However,
phages
have
also
been
reported
no,
and
in
some
cases
even
positive,
effects
on
host
densities.
Here,
we
investigate
the
mechanisms
behind
an
increase
density
Variovorax
sp.
populations
following
a
fixation
of
resistance
that
was
maintained
after
phage
extinction.
Our
results
demonstrate
genetic
trait
coinciding
with
emergence.
Growth
curves
showed
shifted
population
growth
such
higher
death-phase.
This
density-increasing
effect
had
important
implications
for
community
structure
resistant
decreasing
conspecific.
That
lytic
densities
has
wider
ecology
therapy
where
are
presumed
negative
their
hosts.
Language: Английский