Unraveling the Role of Dopaminergic and Calretinin Interneurons in the Olfactory Bulb DOI Creative Commons
Simona Capsoni, Alex Fogli Iseppe, Fabio Casciano

et al.

Frontiers in Neural Circuits, Journal Year: 2021, Volume and Issue: 15

Published: Oct. 8, 2021

The perception and discriminating of odors are sensory activities that an integral part our daily life. first brain region where processed is the olfactory bulb (OB). Among different cell populations make up this area, interneurons play essential role in activity. Moreover, probably because their activity, they represent exception compared to other parts brain, since OB continuously generated postnatal adult period. In review, we will focus on periglomerular (PG) cells which a class found glomerular layer OB. These can be classified into distinct subtypes based neurochemical nature, neurotransmitter calcium-binding proteins expressed by these cells. Dopaminergic (DA) calretinin (CR) among newly important physiology OB, DA involved processing adaptation bulbar network external conditions. main appears inhibition glutamate release from fibers. Calretinin best morphologically characterized PG but little known about function except for inhibitory effect noisy random excitatory signals arriving at neurons. mainly describe electrophysiological properties related excitability profiles CR cells, with particular view differences characterize mature stages neurogenesis.

Language: Английский

Unraveling the Role of Dopaminergic and Calretinin Interneurons in the Olfactory Bulb DOI Creative Commons
Simona Capsoni, Alex Fogli Iseppe, Fabio Casciano

et al.

Frontiers in Neural Circuits, Journal Year: 2021, Volume and Issue: 15

Published: Oct. 8, 2021

The perception and discriminating of odors are sensory activities that an integral part our daily life. first brain region where processed is the olfactory bulb (OB). Among different cell populations make up this area, interneurons play essential role in activity. Moreover, probably because their activity, they represent exception compared to other parts brain, since OB continuously generated postnatal adult period. In review, we will focus on periglomerular (PG) cells which a class found glomerular layer OB. These can be classified into distinct subtypes based neurochemical nature, neurotransmitter calcium-binding proteins expressed by these cells. Dopaminergic (DA) calretinin (CR) among newly important physiology OB, DA involved processing adaptation bulbar network external conditions. main appears inhibition glutamate release from fibers. Calretinin best morphologically characterized PG but little known about function except for inhibitory effect noisy random excitatory signals arriving at neurons. mainly describe electrophysiological properties related excitability profiles CR cells, with particular view differences characterize mature stages neurogenesis.

Language: Английский

Citations

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