Emerging Orchestrator of Ecological Adaptation: m6A Regulation of Post‐Transcriptional Mechanisms DOI Creative Commons
Ehsan Pashay Ahi, Pooja Singh

Molecular Ecology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 5, 2024

ABSTRACT Genetic mechanisms have been at the forefront of our exploration into substrate adaptive evolution and phenotypic diversification. However, genetic variation only accounts for a fraction variation. In last decade, significance RNA modification has become more apparent in context organismal adaptation to rapidly changing environments. m 6 A methylation, most abundant form modification, is emerging as potentially significant player various biological processes. Despite its fundamental function regulate other major post‐transcriptional such microRNA alternative splicing, role ecology understudied. This review highlights potential importance methylation ecological adaptation, emphasising need further research, especially natural systems. We focus on how not affects mRNA fate but also influences miRNA‐mediated gene regulation contributing adaptation. The aim this synthesise key background information enhance understanding driving species survival dynamic environments motivate future research dynamics methylation.

Language: Английский

Evolutionary lability of a key innovation spurs rapid diversification DOI
Nick Peoples, Michael D. Burns, Michalis Mihalitsis

et al.

Nature, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 26, 2025

Language: Английский

Citations

2

Emerging Orchestrator of Ecological Adaptation: m6A Regulation of Post‐Transcriptional Mechanisms DOI Creative Commons
Ehsan Pashay Ahi, Pooja Singh

Molecular Ecology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 5, 2024

ABSTRACT Genetic mechanisms have been at the forefront of our exploration into substrate adaptive evolution and phenotypic diversification. However, genetic variation only accounts for a fraction variation. In last decade, significance RNA modification has become more apparent in context organismal adaptation to rapidly changing environments. m 6 A methylation, most abundant form modification, is emerging as potentially significant player various biological processes. Despite its fundamental function regulate other major post‐transcriptional such microRNA alternative splicing, role ecology understudied. This review highlights potential importance methylation ecological adaptation, emphasising need further research, especially natural systems. We focus on how not affects mRNA fate but also influences miRNA‐mediated gene regulation contributing adaptation. The aim this synthesise key background information enhance understanding driving species survival dynamic environments motivate future research dynamics methylation.

Language: Английский

Citations

4